Publikationen
2024
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Generation and application of novel hES cell reporter lines for the differentiation and maturation of hPS cell-derived islet-like clusters, 27 Aug. 2024, in: Scientific reports. 14, 1, 19863Elektronische (Volltext-)VersionPublikation: Beitrag in Fachzeitschrift > Forschungsartikel
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Regulation of multiple signaling pathways promotes the consistent expansion of human pancreatic progenitors in defined conditions, 5 Jan. 2024, in: eLife. 12, 30 S., RP89962Elektronische (Volltext-)VersionPublikation: Beitrag in Fachzeitschrift > Forschungsartikel
2021
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Debates in Pancreatic Beta Cell Biology: Proliferation Versus Progenitor Differentiation and Transdifferentiation in Restoring β Cell Mass, 6 Aug. 2021, in: Frontiers in endocrinology. 12, 722250Elektronische (Volltext-)VersionPublikation: Beitrag in Fachzeitschrift > Übersichtsartikel (Review)
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The transCampus Metabolic Training Programme Explores the Link of SARS-CoV-2 Virus to Metabolic Disease, März 2021, in: Hormone and metabolic research. 53, 03, S. 204-206, 3 S.Elektronische (Volltext-)VersionPublikation: Beitrag in Fachzeitschrift > Leitartikel (Editorial)
2020
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Hox-dependent coordination of mouse cardiac progenitor cell patterning and differentiation, Aug. 2020, in: eLife. 9, S. 1-32, 32 S., e55124Elektronische (Volltext-)VersionPublikation: Beitrag in Fachzeitschrift > Forschungsartikel
2013
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ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools, 1 Feb. 2013, in: Developmental biology. 374, 1, S. 153-163, 11 S.Elektronische (Volltext-)VersionPublikation: Beitrag in Fachzeitschrift > Forschungsartikel
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Publikationen vor 2012
I. Serafimidis, S. Heximer, D. Beis and A. Gavalas. GPCR signaling and S1P play a phylogenetically conserved role in endocrine pancreas morphogenesis (2011). Mol. Cell. Biol. 31 4442-53 doi: 10.1128/MCB.05702-11.
M. Bami, V. Episkopou, A. Gavalas and M. Gouti. Directed neural differentiation of mouse embryonic stem cells is a sensitive system for the identification of novel Hox gene effectors (2011). PLOS One, 6, e20197 doi: 10.1371/journal.pone.0020197.
M. Gouti, J. Briscoe and A. Gavalas. Anterior Hox genes interact with components of the neural crest specification network to induce neural crest fates (2011). Stem Cells, 29, 858-70 doi: 10.1002/stem.630.
M. Poulou, D. Bell, K. Bozonelos, M. Alexiou, A. Gavalas, R. Lovell-Badge and E. Remboutsika. Development of a chromosomally integrated metabolite-inducible Leu3p-alpha-IPM "off-on" gene switch. (2010). PLOS One, 5, e12488 doi: 10.1371/journal.pone.0012488.
M. Kapasa, I. Serafimidis, A. Gavalas* and S. Kossida*. Identification of phylogenetically conserved enhancer elements implicated in pancreas development in the WISP1 and CTGF orthologs (2008). Genomics 92, 301-308 doi: 10.1016/j.ygeno.2008.06.003 (* joint corresponding authors).
M. Gouti and A. Gavalas. Hoxb1 controls cell fate specification and proliferative capacity of neural stem and progenitor cells (2008). Stem Cells 26, 1985-1997 doi: 10.1634/stemcells.2008-0182.
I. Serafimidis, I. Rakatzi, V. Episkopou, M. Gouti and A. Gavalas. Novel Effectors of Directed and ngn3 Mediated Differentiation of Mouse Embryonic Stem Cells into Endocrine Pancreas Progenitors (2008). Stem Cells 26, 3-16 doi: 10.1634/stemcells.2007-0194.
J. Jacob, A.L. Ferri, C. Milton, F. Prin, P. Pla, W. Lin, A. Gavalas, S.L. Ang and J. Briscoe. Transcriptional repression coordinates the temporal switch from motor to serotonergic neurogenesis (2007). Nat. Neurosci. 10, 1433-9 doi: 10.1038/nn1985.
S. Remacle, L. Abbas, O. d. Backer, N. Pacico, A. Gavalas, F. Gofflot, J. J. Picard, and R. Rezsöhazy. Loss of function but no gain of function caused by amino acid substitutions in the hexapeptide of Hoxa1 in vivo. (2004). Mol. Cell. Biol. 24, 8567-8575 doi: 10.1128/MCB.24.19.8567-8575.2004.
A. Gavalas, C. Ruhrberg, J. Livet, C. Henderson and R. Krumlauf. Neurogenesis defects in the hindbrain of Hox mutants reflect regulatory interactions among Hox genes (2003). Development 130, 5663-5679 doi: 10.1242/dev.00802.
A. Gavalas. arRAnging the hindbrain (2002). Trends in Neurosciences, 25, 59-6 doi: 10.1016/s0166-2236(02)02067-2.
A. Gavalas, P. Trainor, L. Ariza-McNaughton, and R. Krumlauf. Synergy between Hoxa1 and Hoxb1: The relationship between arch patterning and the generation of cranial neural crest (2001). Development 128, 3017-3027 doi: 10.1242/dev.128.15.3017.
G. DiRocco, A. Gavalas, H. Popperl, R.Krumlauf, F. Mavilio and V. Zappavigna. The HOXB1 transcriptional activation domain and the recruitment of a SOX/OCT complex control the cell context-dependent activity of the Hoxb1 autoregulatory enhancer (2001). J. Biol. Chem. 276, 20506-20515 doi: 10.1074/jbc.M011175200.
A. Gavalas and R. Krumlauf. Retinoid signalling and hindbrain patterning (2000). Current Opinion in Genetics & Development 10, 380-386 doi: 10.1016/s0959-437x(00)00100-3.
F.M. Rijli, A. Gavalas and P. Chambon. Segmentation and specification in the branchial region of the head: the role of the Hox selector genes (1998). Int. J. Dev. Biology 42, 393-401.
A. Gavalas, M. Studer, A. Lumsden, F.M. Rijli, R. Krumlauf and P. Chambon. Hoxa1 and Hoxb1 synergize in patterning the hindbrain, cranial nerves and second pharyngeal arch (1998). Development 125, 1123-1136 doi: 10.1242/dev.125.6.1123.
M. Studer, A. Gavalas, H. Marshall, L. Ariza McNaughton, F.M. Rijli, P. Chambon and R. Krumlauf. Genetic interactions betweenHoxa1 and Hoxb1 reveal new roles in regulation of early hindbrain patterning (1998). Development 125, 1025-1036 doi: 10.1242/dev.125.6.1025.
A. Gavalas, M. Davenne, A. Lumsden, P. Chambon and F.M. Rijli. Control of axon guidance and rostral hindbrain patterning by Hoxa-2. (1997). Development, 124, 3693-3702 doi: 10.1242/dev.124.19.3693.