Non-OTS Papers

As part of our commitment to scientific independence and recognition, we are proud to celebrate our group members who are publishing as co-corresponding authors, or writing fully independent articles, based on work done in our labs.

Non-OTS Highlights from the group

• J Felber; Switching-On Cancer Drugs. Nachrichten aus der Chemie 2024, 72, 59-61.
• L Zeisel; Chemical probes of redox enzymes by rational, reactivity-based design. Chem 2022, 8, 1167-1169.

Co-Corresponding Authorships from the group

• L Zeisel*, L Dessen Weissenhorn, K Scholzen, A Madabeni, L Orian, E Arner, O Thorn-Seshold*; Bicyclic selenenyl sulfides tune stepwise thiol/selenol rates to reveal cellular constraints for bioreductive probes targeting mammalian thioredoxin reductase. ChemRxiv 2025 (doi.org/n8h6)

• M Müller*, A Valavalkar, V Gujrati, JP Prohaska, D Shelar, M Kaltenegger, B Dietzek-Ivanšić, V Ntziachristos, O Thorn-Seshold*; Molecular rotors are loud, highly photostable, NIR/SWIR- active molecular optoacoustic contrast agents. ChemRxiv 2024 (doi.org/ntpt).

• M Reynders*, S Willems, J Marschner, T Wein, D Merk*, O Thorn-Seshold*; A High-Quality Photoswitchable Probe that Selectively and Potently Regulates the Transcription Factor RORγ. Angewandte 2024, e202410139.

• O Thorn-Seshold*, J Felber*, L Zeisel*; Cyclic Dichalcogenide ADC Linker Units and Uses Thereof. US Patent Application 2024, 18/587313.

• L Zeisel*, M Maier, O Thorn-Seshold*; Regioselective, efficient and scalable syntheses of 1,2-thiaselenanes. Synthesis 2023, 1385-1393.

• J Felber*, O Thorn-Seshold*; 40 Years of Duocarmycins: A Graphical Structure/Function Review of Their Chemical Evolution, from SAR to Prodrugs and ADCs. JACS Au 2022, 2636–2644 (ACS Editor's Choice).

OTS papers prior to independent research

• A Robust, High-Sensitivity Stealth Probe for Peptidases. O Thorn-Seshold, M Vargas-Sanchez, S McKeon, J Hasserodt. Chem. Comm. 2012, 48, 6253-6255.
• Fluorogenic Peptidase Substrate. J Hasserodt, O Thorn-Seshold. Patent WO2013045854, 2011.
• Models for randomly hyperbranched polymers: Theory and simulation. D Konkolewicz, O Thorn-Seshold, A Gray-Weale. J. Chem. Phys. 2008, 129, 054901.
• A systematic study of ligand intermolecular interactions in crystals of copper(II) complexes of bidentate guanidino derivatives. MM Bishop, LF Lindoy, M McPartlin, A Parkin, O Thorn-Seshold, P Turner. Polyhedron 2007, 26, (2), 415-429.
• A Structural Study of Tautomerism and Hydrogen-Bonding in Supramolecular Assemblies. MM Bishop, SJ Coles, A Lee, LF Lindoy, A Parkin, O Thorn-Seshold, P Turner. Supramol. Chem. 2005, 17, (7), 567-578.
• A Supramolecular Assembly Containing an Unusually Short N-H∙∙∙N Hydrogen Bond. MM Bishop, LF Lindoy, O Thorn-Seshold, RO Piltz, P Turner. J. Het. Chem. 2001, 38, (6), 1377-1382.