B CUBE Single Molecule Microscopy

A microscope image. Elongated, ridge-like structures extend from the bottom right to the top left. They are dark brown in low areas with yellow and white at pointed, high areas. — AFM topography scan of a diatom valve carried out at the JPK NanoWizard4 of the MIM Facility at B CUBE.

The B CUBE single molecule microscopy facility offers users access to a range of microscopy techniques to identify and characterize the relationship between structure and function at the molecular level.

In the field of imaging, this includes atomic force microscopy (AFM) and optical microscopy, with techniques such as super-resolution single molecule localization microscopy (SMLM, e.g. STORM/PALM/...), total internal reflection fluorescence microscopy (TIRF), confocal spinning disk microscopy, and ordinary epifluorescence microscopy. Single-molecule techniques such as single-particle tracking (SPT), Förster resonance energy transfer (FRET) are offered together with the necessary expertise for analysis.

If you have specific requests or you need training or technical support please contact us. You will find the specific contact persons at the equipment page.