Statusvortrag von Herrn Jan Tiemann

Abstract: 

Fluorescence microscopy (FM) is a 3D imaging technique in cell biology that not only captures high-resolution images but also enables precise manipulation of the sample using focused light. However, as FM continues to evolve, traditional 2D interfaces are increasingly limiting the full utilisation of the technology. Meanwhile, Extended Reality (XR) interfaces are rapidly becoming more accessible and affordable, both in terms of cost and programming requirements. Upon examining the landscape of FM applications, we address two challenges that can be effectively addressed with the integration of XR interfaces into microscopy. First, live control of a 3D microscope with real-time visualisation of image data in an immersive 3D space greatly facilitates "stage exploration" and the identification of regions of interest for the experimenter. This is particularly important when working with large or sparse samples under high magnification, or with cutting-edge microscope systems like SCAPE, which produce non-axis aligned images. By leveraging XR interfaces and displays, experimenters can more easily navigate and analyze complex datasets, leading to faster and more accurate results. Secondly, XR enables 3D sample manipulations that would be very difficult to design and execute with traditional 2D interfaces. We demonstrate the use of XR to perform 3D laser ablation manipulations and validated it through a microscopy expert review study. We conclude that the convergence of FM and XR presents a unique opportunity to revolutionize the field of cell biology.

Betreuer: Jun. Prof. Matthew McGinity 
Fachreferent: Dr. Ulrik Günther (CASUS)