Seifert Lab: Bioinformatics Core Unit
The fast progress in the development of experimental technologies enables to measure molecular data of complex diseases with unprecedented detail. The analysis of such heterogeneous data sets requires specific bioinformatics tools to disentangle the complex interplay of different regulatory layers associated with disease-causing processes.
The Bioinformatics Core Unit develops innovative bioinformatics and systems biology methods for the integrative analysis of molecular high-throughput data. We focus on the development of network-based methods and probabilistic models to better understand molecular mechanisms of disease development (e.g. tumors).
We further offer a comprehensive bioinformatics consulting and support the analysis of molecular high-throughput data (e.g. microarrays, next-generation sequencing).
Research focus
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Network-based methods and probabilistic models for the integrative analysis of heterogeneous molecular high-throughput data
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Development of astrozytomas and oligodendrogliomas
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Differences between brain- and non-brain metastases of melanomas
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Development of radioresistance of prostate cancer
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Differences in therapy outcomes of acute myeloid leukemia
Projects
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GliOmics — Integrative analysis of glioma omics data (TU Dresden, basic funding, National Center for Tumor Diseases (NCT) Dresden, Else Kröner Graduate School)
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MelanOmics — Integrative analysis of omics data of melanoma metastases (National Center for Tumor Diseases (NCT) Dresden)
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SyTASC — Systems-based Therapy of AML Stem Cells (Deutsche Krebshilfe e.V.)
Group leader
© Michael Seifert
Group leader
NameMr Dr. rer. nat. Michael Seifert
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 458-6056
- fax Fax
- +49 351 458-7222
Members of the research group
© Lisa Schöne
Research fellow (external: NCT)
NameMs Lisa Schöne M.Sc.
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 458-6060
- fax Fax
- +49 351 458-7222
© Pirasteh Pahlavan
Research fellow (external: NCT)
NameMs Dr. rer. nat. Pirasteh Pahlavan
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 458-6228
- fax Fax
- +49 351 458-7222
Students (MD/ Ph.D. students, student assistants)
MD student
NameMr Josef Gladitz
Else-Kröner-Stiftung
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 458-6060
- fax Fax
- +49 351 458-7222
© Annemarie Schwarz
MD student
NameMs Annemarie Schwarz
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 458-6060
- fax Fax
- +49 351 458-7222
Former staff members
© Chris Lauber
Research fellow
NameMr Dr. Chris Lauber
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 458-6055
- fax Fax
- +49 351 458-7222
student assistant
NameMs Olena Maiakovska B.Sc.
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- work Tel.
- +49 351 458-6060
- fax Fax
- +49 351 458-7222
student assistant
NameMr Assad Majid B.Sc.
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 458-6060
- fax Fax
- +49 351 458-7222
Ph.D. student
NameMr Adrian Ortiz Cervantes M.Sc.
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- work Tel.
- +49 351 458-6230
- fax Fax
- +49 351 458-7222
Student assistant
NameMr Michael Rank
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