Publications of the PLID since 2013

Publications 2021

Publications 2020

Publications 2019

2021

Schumann T, König J, von Loeffelholz C, Vatner DF, Zhang D, Perry RJ, Bernier M, Chami J, Henke C, Kurzbach A, El-Agroudy NN, Willmes DM, Pesta D, de Cabo R, O Sullivan JF, Simon E, Shulman GI, Hamilton BS, Birkenfeld AL. Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance. Commun Biol. 2021

Janke U, Mitlehner A, Weide A, Gutmann T, Delcea M. Reconstitution of Functional Integrin αIIbβ3 and Its Activation in Plasma Membrane-Mimetic Lipid Environments. Membranes (Basel). 2021

Wigger L, Barovic M, Brunner AD, Marzetta F, Schöniger E, Mehl F, Kipke N, Friedland D, Burdet F, Kessler C, Lesche M, Thorens B, Bonifacio E, Legido-Quigley C, Barbier Saint Hilaire P, Delerive P, Dahl A, Klose C, Gerl MJ, Simons K, Aust D, Weitz J, Distler M, Schulte AM, Mann M, Ibberson M, Solimena M. Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes. Nat Metab. 2021

Bornstein SR, Voit-Bak K, Donate T, Rodionov RN, Gainetdinov RR, Tselmin S, Kanczkowski W, Müller GM, Achleitner M, Wang J, Licinio J, Bauer M, Young AH, Thuret S, Bechmann N, Straube R. Chronic post-COVID-19 syndrome and chronic fatigue syndrome: Is there a role for extracorporeal apheresis? Mol Psychiatry. 2021

Sormendi S, Deygas M, Sinha A, Bernard M, Krüger A, Kourtzelis I, Le Lay G, Sáez PJ, Gerlach M, Franke K, Meneses A, Kräter M, Palladini A, Guck J, Coskun Ü, Chavakis T, Vargas P, Wielockx B. HIF2α is a direct regulator of neutrophil motility. Blood. 2021

Steenblock C, Richter S, Berger I, Barovic M, Schmid J, Schubert U, Jarzebska N, von Mässenhausen A, Linkermann A, Schürmann A, Pablik J, Dienemann T, Evert K, Rodionov RN, Semenova NY, Zinserling VA, Gainetdinov RR, Baretton G, Lindemann D, Solimena M, Ludwig B, Bornstein SR. Viral infiltration of pancreatic islets in patients with COVID-19. Nat Commun. 2021

Chen J, Spracklen CN, Marenne G, Varshney A, Corbin LJ, Luan J, Willems SM, Wu Y, Zhang X, Horikoshi M, Boutin TS, Mägi R, Waage J, Li-Gao R, Chan KHK, Yao J, Anasanti MD, Chu AY, Claringbould A, Heikkinen J, Hong J, Hottenga JJ, Huo S, Kaakinen MA, Louie T, März W, Moreno-Macias H, Ndungu A, Nelson SC, Nolte IM, North KE, Raulerson CK, Ray D, Rohde R, Rybin D, Schurmann C, Sim X, Southam L, Stewart ID, Wang CA, Wang Y, Wu P, Zhang W, Ahluwalia TS, Appel EVR, Bielak LF, Brody JA, Burtt NP, Cabrera CP, Cade BE, Chai JF, Chai X, Chang LC, Chen CH, Chen BH, Chitrala KN, Chiu YF, de Haan HG, Delgado GE, Demirkan A, Duan Q, Engmann J, Fatumo SA, Gayán J, Giulianini F, Gong JH, Gustafsson S, Hai Y, Hartwig FP, He J, Heianza Y, Huang T, Huerta-Chagoya A, Hwang MY, Jensen RA, Kawaguchi T, Kentistou KA, Kim YJ, Kleber ME, Kooner IK, Lai S, Lange LA, Langefeld CD, Lauzon M, Li M, Ligthart S, Liu J, Loh M, Long J, Lyssenko V, Mangino M, Marzi C, Montasser ME, Nag A, Nakatochi M, Noce D, Noordam R, Pistis G, Preuss M, Raffield L, Rasmussen-Torvik LJ, Rich SS, Robertson NR, Rueedi R, Ryan K, Sanna S, Saxena R, Schraut KE, Sennblad B, Setoh K, Smith AV, Sparsø T, Strawbridge RJ, Takeuchi F, Tan J, Trompet S, van den Akker E, van der Most PJ, Verweij N, Vogel M, Wang H, Wang C, Wang N, Warren HR, Wen W, Wilsgaard T, Wong A, Wood AR, Xie T, Zafarmand MH, Zhao JH, Zhao W, Amin N, Arzumanyan Z, Astrup A, Bakker SJL, Baldassarre D, Beekman M, Bergman RN, Bertoni A, Blüher M, Bonnycastle LL, Bornstein SR, Bowden DW, Cai Q, Campbell A, Campbell H, Chang YC, de Geus EJC, Dehghan A, Du S, Eiriksdottir G, Farmaki AE, Frånberg M, Fuchsberger C, Gao Y, Gjesing AP, Goel A, Han S, Hartman CA, Herder C, Hicks AA, Hsieh CH, Hsueh WA, Ichihara S, Igase M, Ikram MA, Johnson WC, Jørgensen ME, Joshi PK, Kalyani RR, Kandeel FR, Katsuya T, Khor CC, Kiess W, Kolcic I, Kuulasmaa T, Kuusisto J, Läll K, Lam K, Lawlor DA, Lee NR, Lemaitre RN, Li H; Lifelines Cohort Study, Lin SY, Lindström J, Linneberg A, Liu J, Lorenzo C, Matsubara T, Matsuda F, Mingrone G, Mooijaart S, Moon S, Nabika T, Nadkarni GN, Nadler JL, Nelis M, Neville MJ, Norris JM, Ohyagi Y, Peters A, Peyser PA, Polasek O, Qi Q, Raven D, Reilly DF, Reiner A, Rivideneira F, Roll K, Rudan I, Sabanayagam C, Sandow K, Sattar N, Schürmann A, Shi J, Stringham HM, Taylor KD, Teslovich TM, Thuesen B, Timmers PRHJ, Tremoli E, Tsai MY, Uitterlinden A, van Dam RM, van Heemst D, van Hylckama Vlieg A, van Vliet-Ostaptchouk JV, Vangipurapu J, Vestergaard H, Wang T, Willems van Dijk K, Zemunik T, Abecasis GR, Adair LS, Aguilar-Salinas CA, Alarcón-Riquelme ME, An P, Aviles-Santa L, Becker DM, Beilin LJ, Bergmann S, Bisgaard H, Black C, Boehnke M, Boerwinkle E, Böhm BO, Bønnelykke K, Boomsma DI, Bottinger EP, Buchanan TA, Canouil M, Caulfield MJ, Chambers JC, Chasman DI, Chen YI, Cheng CY, Collins FS, Correa A, Cucca F, de Silva HJ, Dedoussis G, Elmståhl S, Evans MK, Ferrannini E, Ferrucci L, Florez JC, Franks PW, Frayling TM, Froguel P, Gigante B, Goodarzi MO, Gordon-Larsen P, Grallert H, Grarup N, Grimsgaard S, Groop L, Gudnason V, Guo X, Hamsten A, Hansen T, Hayward C, Heckbert SR, Horta BL, Huang W, Ingelsson E, James PS, Jarvelin MR, Jonas JB, Jukema JW, Kaleebu P, Kaplan R, Kardia SLR, Kato N, Keinanen-Kiukaanniemi SM, Kim BJ, Kivimaki M, Koistinen HA, Kooner JS, Körner A, Kovacs P, Kuh D, Kumari M, Kutalik Z, Laakso M, Lakka TA, Launer LJ, Leander K, Li H, Lin X, Lind L, Lindgren C, Liu S, Loos RJF, Magnusson PKE, Mahajan A, Metspalu A, Mook-Kanamori DO, Mori TA, Munroe PB, Njølstad I, O'Connell JR, Oldehinkel AJ, Ong KK, Padmanabhan S, Palmer CNA, Palmer ND, Pedersen O, Pennell CE, Porteous DJ, Pramstaller PP, Province MA, Psaty BM, Qi L, Raffel LJ, Rauramaa R, Redline S, Ridker PM, Rosendaal FR, Saaristo TE, Sandhu M, Saramies J, Schneiderman N, Schwarz P, Scott LJ, Selvin E, Sever P, Shu XO, Slagboom PE, Small KS, Smith BH, Snieder H, Sofer T, Sørensen TIA, Spector TD, Stanton A, Steves CJ, Stumvoll M, Sun L, Tabara Y, Tai ES, Timpson NJ, Tönjes A, Tuomilehto J, Tusie T, Uusitupa M, van der Harst P, van Duijn C, Vitart V, Vollenweider P, Vrijkotte TGM, Wagenknecht LE, Walker M, Wang YX, Wareham NJ, Watanabe RM, Watkins H, Wei WB, Wickremasinghe AR, Willemsen G, Wilson JF, Wong TY, Wu JY, Xiang AH, Yanek LR, Yengo L, Yokota M, Zeggini E, Zheng W, Zonderman AB, Rotter JI, Gloyn AL, McCarthy MI, Dupuis J, Meigs JB, Scott RA, Prokopenko I, Leong A, Liu CT, Parker SCJ, Mohlke KL, Langenberg C, Wheeler E, Morris AP, Barroso I; Meta-Analysis of Glucose and Insulin-related Traits Consortium (MAGIC). The trans-ancestral genomic architecture of glycemic traits. Nat Genet. 2021

Breunig M, Merkle J, Wagner M, Melzer MK, Barth TFE, Engleitner T, Krumm J, Wiedenmann S, Cohrs CM, Perkhofer L, Jain G, Krüger J, Hermann PC, Schmid M, Madácsy T, Varga Á, Griger J, Azoitei N, Müller M, Wessely O, Robey PG, Heller S, Dantes Z, Reichert M, Günes C, Bolenz C, Kuhn F, Maléth J, Speier S, Liebau S, Sipos B, Kuster B, Seufferlein T, Rad R, Meier M, Hohwieler M, Kleger A. Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells. Cell Stem Cell. 2021

Lechner K, Lechner B, Crispin A, Schwarz PEH, von Bibra H. Waist-to-height ratio and metabolic phenotype compared to the Matsuda index for the prediction of insulin resistance. Sci Rep. 2021

Huber MK, Drotar DM, Hiller H, Beery ML, Joseph P, Kusmartseva I, Speier S, Atkinson MA, Mathews CE, Phelps EA. Observing Islet Function and Islet-Immune Cell Interactions in Live Pancreatic Tissue Slices. J Vis Exp. 2021

Hippich M, Sifft P, Zapardiel-Gonzalo J, Böhmer MM, Lampasona V, Bonifacio E, Ziegler AG. A Public Health Antibody Screening Indicates a Marked Increase of SARS-CoV-2 Exposure Rate in Children during the Second Wave. Med (N Y). 2021

Ahuja V, Aronen P, Pramodkumar TA, Looker H, Chetrit A, Bloigu AH, Juutilainen A, Bianchi C, La Sala L, Anjana RM, Pradeepa R, Venkatesan U, Jebarani S, Baskar V, Fiorentino TV, Timpel P, DeFronzo RA, Ceriello A, Del Prato S, Abdul-Ghani M, Keinänen-Kiukaanniemi S, Dankner R, Bennett PH, Knowler WC, Schwarz P, Sesti G, Oka R, Mohan V, Groop L, Tuomilehto J, Ripatti S, Bergman M, Tuomi T. Accuracy of 1-Hour Plasma Glucose During the Oral Glucose Tolerance Test in Diagnosis of Type 2 Diabetes in Adults: A Meta-analysis. Diabetes Care. 2021

Ansarullah, Jain C, Far FF, Homberg S, Wißmiller K, von Hahn FG, Raducanu A, Schirge S, Sterr M, Bilekova S, Siehler J, Wiener J, Oppenländer L, Morshedi A, Bastidas-Ponce A, Collden G, Irmler M, Beckers J, Feuchtinger A, Grzybek M, Ahlbrecht C, Feederle R, Plettenburg O, Müller TD, Meier M, Tschöp MH, Coskun Ü, Lickert H. Author Correction: Inceptor counteracts insulin signalling in β-cells to control glycaemia. Nature. 2021

Durán C, Ciucci S, Palladini A, Ijaz UZ, Zippo AG, Sterbini FP, Masucci L, Cammarota G, Ianiro G, Spuul P, Schroeder M, Grill SW, Parsons BN, Pritchard DM, Posteraro B, Sanguinetti M, Gasbarrini G, Gasbarrini A, Cannistraci CV. Nonlinear machine learning pattern recognition and bacteria-metabolite multilayer network analysis of perturbed gastric microbiome. Nat Commun. 2021

Bornstein SR, Guan K, Brunßen C, Mueller G, Kamvissi-Lorenz V, Lechler R, Trembath R, Mayr M, Poston L, Sancho R; IRTG Study Group:, Ahmed S, Alfar E, Aljani B, Alves TC, Amiel S, Andoniadou CL, Bandral M, Belavgeni A, Berger I, Birkenfeld A, Bonifacio E, Chavakis T, Chawla P, Choudhary P, Cujba AM, Delgadillo Silva LF, Demcollari T, Drotar DM, Duin S, El-Agroudy NN, El-Armouche A, Eugster A, Gado M, Gavalas A, Gelinsky M, Guirgus M, Hansen S, Hanton E, Hasse M, Henneicke H, Heller C, Hempel H, Hogstrand C, Hopkins D, Jarc L, Jones PM, Kamel M, Kämmerer S, King AJF, Kurzbach A, Lambert C, Latunde-Dada Y, Lieberam I, Liers J, Li JW, Linkermann A, Locke S, Ludwig B, Manea T, Maremonti F, Marinicova Z, McGowan BM, Mickunas M, Mingrone G, Mohanraj K, Morawietz H, Ninov N, Peakman M, Persaud SJ, Pietzsch J, Cachorro E, Pullen TJ, Pyrina I, Rubino F, Santambrogio A, Schepp F, Schlinkert P, Scriba LD, Siow R, Solimena M, Spagnoli FM, Speier S, Stavridou A, Steenblock C, Strano A, Taylor P, Tiepner A, Tonnus W, Tree T, Watt F, Werdermann M, Wilson M, Yusuf N, Ziegler CG. The transCampus Metabolic Training Programme Explores the Link of SARS-CoV-2 Virus to Metabolic Disease. Horm Metab Res. 2021

Henke C, Haufe S, Ziehl D, Bornstein SR, Schulz-Menger J, Heni M, Engeli S, Jordan J, Birkenfeld AL. Low-fat hypocaloric diet reduces neprilysin in overweight and obese human subjects. ESC Heart Fail. 2021

Bornstein SR, Rubino F, Ludwig B, Rietzsch H, Schwarz PEH, Rodionov RN, Khunti K, Hopkins D, Birkenfeld AL, Boehm B, Amiel S, Holt RIG, Skyler JS, DeVries JH, Renard E, Eckel RH, Zimmet P, Alberti KG, Geloneze B, Chan JC, Mbanya JC, Onyegbutulem HC, Ramachandran A, Basit A, Hassanein M, Spinas GA, Beuschlein F, Mingrone G. Consequences of the COVID-19 pandemic for patients with metabolic diseases. Nat Metab. 2021

Bonifacio E, Weiß A, Winkler C, Hippich M, Rewers MJ, Toppari J, Lernmark Å, She JX, Hagopian WA, Krischer JP, Vehik K, Schatz DA, Akolkar B, Ziegler AG; TEDDY Study Group. An Age-Related Exponential Decline in the Risk of Multiple Islet Autoantibody Seroconversion During Childhood. Diabetes Care. 2021

Sormendi S, Deygas M, Sinha A, Bernard MLM, Krüger A, Koutzelis I, Le Lay GM, Sáez PJ, Gerlach M, Franke K, Meneses A, Kräter M, Palladini A, Guck J, Coskun Ü, Chavakis T, Vargas P, Wielockx B. HIF2α is a Direct Regulator of Neutrophil Motility. Blood. 2021

Lagou V, Mägi R, Hottenga JJ, Grallert H, Perry JRB, Bouatia-Naji N, Marullo L, Rybin D, Jansen R, Min JL, Dimas AS, Ulrich A, Zudina L, Gådin JR, Jiang L, Faggian A, Bonnefond A, Fadista J, Stathopoulou MG, Isaacs A, Willems SM, Navarro P, Tanaka T, Jackson AU, Montasser ME, O'Connell JR, Bielak LF, Webster RJ, Saxena R, Stafford JM, Pourcain BS, Timpson NJ, Salo P, Shin SY, Amin N, Smith AV, Li G, Verweij N, Goel A, Ford I, Johnson PCD, Johnson T, Kapur K, Thorleifsson G, Strawbridge RJ, Rasmussen-Torvik LJ, Esko T, Mihailov E, Fall T, Fraser RM, Mahajan A, Kanoni S, Giedraitis V, Kleber ME, Silbernagel G, Meyer J, Müller-Nurasyid M, Ganna A, Sarin AP, Yengo L, Shungin D, Luan J, Horikoshi M, An P, Sanna S, Boettcher Y, Rayner NW, Nolte IM, Zemunik T, Iperen EV, Kovacs P, Hastie ND, Wild SH, McLachlan S, Campbell S, Polasek O, Carlson O, Egan J, Kiess W, Willemsen G, Kuusisto J, Laakso M, Dimitriou M, Hicks AA, Rauramaa R, Bandinelli S, Thorand B, Liu Y, Miljkovic I, Lind L, Doney A, Perola M, Hingorani A, Kivimaki M, Kumari M, Bennett AJ, Groves CJ, Herder C, Koistinen HA, Kinnunen L, Faire U, Bakker SJL, Uusitupa M, Palmer CNA, Jukema JW, Sattar N, Pouta A, Snieder H, Boerwinkle E, Pankow JS, Magnusson PK, Krus U, Scapoli C, de Geus EJCN, Blüher M, Wolffenbuttel BHR, Province MA, Abecasis GR, Meigs JB, Hovingh GK, Lindström J, Wilson JF, Wright AF, Dedoussis GV, Bornstein SR, Schwarz PEH, Tönjes A, Winkelmann BR, Boehm BO, März W, Metspalu A, Price JF, Deloukas P, Körner A, Lakka TA, Keinanen-Kiukaanniemi SM, Saaristo TE, Bergman RN, Tuomilehto J, Wareham NJ, Langenberg C, Männistö S, Franks PW, Hayward C, Vitart V, Kaprio J, Visvikis-Siest S, Balkau B, Altshuler D, Rudan I, Stumvoll M, Campbell H, van Duijn CM, Gieger C, Illig T, Ferrucci L, Pedersen NL, Pramstaller PP, Boehnke M, Frayling TM, Shuldiner AR, Peyser PA, Kardia SLR, Palmer LJ, Penninx BW, Meneton P, Harris TB, Navis G, Harst PV, Smith GD, Forouhi NG, Loos RJF, Salomaa V, Soranzo N, Boomsma DI, Groop L, Tuomi T, Hofman A, Munroe PB, Gudnason V, Siscovick DS, Watkins H, Lecoeur C, Vollenweider P, Franco-Cereceda A, Eriksson P, Jarvelin MR, Stefansson K, Hamsten A, Nicholson G, Karpe F, Dermitzakis ET, Lindgren CM, McCarthy MI, Froguel P, Kaakinen MA, Lyssenko V, Watanabe RM, Ingelsson E, Florez JC, Dupuis J, Barroso I, Morris AP, Prokopenko I; Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC). Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Nat Commun. 2021

Hu M, Cebola I, Carrat G, Jiang S, Nawaz S, Khamis A, Canouil M, Froguel P, Schulte A, Solimena M, Ibberson M, Marchetti P, Cardenas-Diaz FL, Gadue PJ, Hastoy B, Alemeida-Souza L, McMahon H, Rutter GA. Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion. Cell Rep. 2021

Müller A, Schmidt D, Xu CS, Pang S, D'Costa JV, Kretschmar S, Münster C, Kurth T, Jug F, Weigert M, Hess HF, Solimena M. 3D FIB-SEM reconstruction of microtubule-organelle interaction in whole primary mouse β cells. J Cell Biol. 2021

Ziegler AG, Bonifacio E. Shortening the paths to type 1 diabetes mellitus prevention. Nat Rev Endocrinol. 2021

Assfalg R, Knoop J, Hoffman KL, Pfirrmann M, Zapardiel-Gonzalo JM, Hofelich A, Eugster A, Weigelt M, Matzke C, Reinhardt J, Fuchs Y, Bunk M, Weiss A, Hippich M, Halfter K, Hauck SM, Hasford J, Petrosino JF, Achenbach P, Bonifacio E, Ziegler AG. Oral insulin immunotherapy in children at risk for type 1 diabetes in a randomised controlled trial. Diabetologia. 2021

Ansarullah, Jain C, Far FF, Homberg S, Wißmiller K, von Hahn FG, Raducanu A, Schirge S, Sterr M, Bilekova S, Siehler J, Wiener J, Oppenländer L, Morshedi A, Bastidas-Ponce A, Collden G, Irmler M, Beckers J, Feuchtinger A, Grzybek M, Ahlbrecht C, Feederle R, Plettenburg O, Müller TD, Meier M, Tschöp MH, Coskun Ü, Lickert H. Inceptor counteracts insulin signalling in β-cells to control glycaemia. Nature. 2021

Willmes DM, Daniels M, Kurzbach A, Lieske S, Bechmann N, Schumann T, Henke C, El-Agroudy NN, Da Costa Goncalves AC, Peitzsch M, Hofmann A, Kanczkowski W, Kräker K, Müller DN, Morawietz H, Deussen A, Wagner M, El-Armouche A, Helfand SL, Bornstein SR, de Cabo R, Bernier M, Eisenhofer G, Tank J, Jordan J, Birkenfeld AL. The longevity gene mIndy (I'm Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms. JCI Insight. 2021

Hazini A, Dieringer B, Pryshliak M, Knoch KP, Heimann L, Tolksdorf B, Pappritz K, El-Shafeey M, Solimena M, Beling A, Kurreck J, Klingel K, Fechner H. miR-375- and miR-1-Regulated Coxsackievirus B3 Has No Pancreas and Heart Toxicity But Strong Antitumor Efficiency in Colorectal Carcinomas. Hum Gene Ther. 2021

Lagou V, Mägi R, Hottenga JJ, Grallert H, Perry JRB, Bouatia-Naji N, Marullo L, Rybin D, Jansen R, Min JL, Dimas AS, Ulrich A, Zudina L, Gådin JR, Jiang L, Faggian A, Bonnefond A, Fadista J, Stathopoulou MG, Isaacs A, Willems SM, Navarro P, Tanaka T, Jackson AU, Montasser ME, O'Connell JR, Bielak LF, Webster RJ, Saxena R, Stafford JM, Pourcain BS, Timpson NJ, Salo P, Shin SY, Amin N, Smith AV, Li G, Verweij N, Goel A, Ford I, Johnson PCD, Johnson T, Kapur K, Thorleifsson G, Strawbridge RJ, Rasmussen-Torvik LJ, Esko T, Mihailov E, Fall T, Fraser RM, Mahajan A, Kanoni S, Giedraitis V, Kleber ME, Silbernagel G, Meyer J, Müller-Nurasyid M, Ganna A, Sarin AP, Yengo L, Shungin D, Luan J, Horikoshi M, An P, Sanna S, Boettcher Y, Rayner NW, Nolte IM, Zemunik T, Iperen EV, Kovacs P, Hastie ND, Wild SH, McLachlan S, Campbell S, Polasek O, Carlson O, Egan J, Kiess W, Willemsen G, Kuusisto J, Laakso M, Dimitriou M, Hicks AA, Rauramaa R, Bandinelli S, Thorand B, Liu Y, Miljkovic I, Lind L, Doney A, Perola M, Hingorani A, Kivimaki M, Kumari M, Bennett AJ, Groves CJ, Herder C, Koistinen HA, Kinnunen L, Faire U, Bakker SJL, Uusitupa M, Palmer CNA, Jukema JW, Sattar N, Pouta A, Snieder H, Boerwinkle E, Pankow JS, Magnusson PK, Krus U, Scapoli C, de Geus EJCN, Blüher M, Wolffenbuttel BHR, Province MA, Abecasis GR, Meigs JB, Hovingh GK, Lindström J, Wilson JF, Wright AF, Dedoussis GV, Bornstein SR, Schwarz PEH, Tönjes A, Winkelmann BR, Boehm BO, März W, Metspalu A, Price JF, Deloukas P, Körner A, Lakka TA, Keinanen-Kiukaanniemi SM, Saaristo TE, Bergman RN, Tuomilehto J, Wareham NJ, Langenberg C, Männistö S, Franks PW, Hayward C, Vitart V, Kaprio J, Visvikis-Siest S, Balkau B, Altshuler D, Rudan I, Stumvoll M, Campbell H, van Duijn CM, Gieger C, Illig T, Ferrucci L, Pedersen NL, Pramstaller PP, Boehnke M, Frayling TM, Shuldiner AR, Peyser PA, Kardia SLR, Palmer LJ, Penninx BW, Meneton P, Harris TB, Navis G, Harst PV, Smith GD, Forouhi NG, Loos RJF, Salomaa V, Soranzo N, Boomsma DI, Groop L, Tuomi T, Hofman A, Munroe PB, Gudnason V, Siscovick DS, Watkins H, Lecoeur C, Vollenweider P, Franco-Cereceda A, Eriksson P, Jarvelin MR, Stefansson K, Hamsten A, Nicholson G, Karpe F, Dermitzakis ET, Lindgren CM, McCarthy MI, Froguel P, Kaakinen MA, Lyssenko V, Watanabe RM, Ingelsson E, Florez JC, Dupuis J, Barroso I, Morris AP, Prokopenko I; Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC). Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Nat Commun. 2021

2020

Tang X, Kusmartseva I, Kulkarni S, Posgai A, Speier S, Schatz DA, Haller MJ, Campbell-Thompson M, Wasserfall CH, Roep BO, Kaddis JS, Atkinson MA. Image-Based Machine Learning Algorithms for Disease Characterization in the Human Type 1 Diabetes Pancreas. Am J Pathol. 2020

Peitzsch C, Gorodetska I, Klusa D, Shi Q, Alves TC, Pantel K, Dubrovska A. Metabolic regulation of prostate cancer heterogeneity and plasticity. Semin Cancer Biol. 2020

Marselli L, Piron A, Suleiman M, Colli ML, Yi X, Khamis A, Carrat GR, Rutter GA, Bugliani M, Giusti L, Ronci M, Ibberson M, Turatsinze JV, Boggi U, De Simone P, De Tata V, Lopes M, Nasteska D, De Luca C, Tesi M, Bosi E, Singh P, Campani D, Schulte AM, Solimena M, Hecht P, Rady B, Bakaj I, Pocai A, Norquay L, Thorens B, Canouil M, Froguel P, Eizirik DL, Cnop M, Marchetti P. Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes. Cell Rep. 2020

Ziegler AG, Bonifacio E. Shortening the paths to type 1 diabetes mellitus prevention. Nat Rev Endocrinol. 2020

Noseda ACD, Rodrigues LS, Targa ADS, Ilkiw JL, Fagotti J, Dos Santos PD, Cecon E, Markus RP, Solimena M, Jockers R, Lima MMS. MT2 melatonin receptors expressed in the olfactory bulb modulate depressive-like behavior and olfaction in the 6-OHDA model of Parkinson's disease. Eur J Pharmacol. 2020

Hippich M, Holthaus L, Assfalg R, Zapardiel Gonzalo JM, Kapfelsperger H, Heigermoser M, Haupt F, Ewald DA, Welzhofer TC, Marcus BA, Heck S, Koelln A, Stock J, Voss F, Secchi M, Piemonti L, Rosa K, Protzer U, Boehmer M, Achenbach P, Lampasona V, Bonifacio E, Ziegler AG. Public health antibody screening indicates a six-fold higher SARS-CoV-2 exposure rate than reported cases in children. Med (N Y). 2020

Imam A, Winnebeck EC, Buchholz N, Froguel P, Bonnefond A, Solimena M, Ivanova A, Bouvier M, Plouffe B, Charpentier G, Karamitri A, Jockers R, Roenneberg T, Vetter C. Circadian, Sleep and Caloric Intake Phenotyping in Type 2 Diabetes Patients With Rare Melatonin Receptor 2 Mutations and Controls: A Pilot Study. Front Physiol. 2020

Chen C, Rawat D, Samikannu B, Bender M, Preissner KT, Linn T. Platelet Glycoprotein VI dependent Thrombus Stabilization is Essential for the Intraportal Engraftment of Pancreatic Islets. Am J Transplant. 2020

Chwastek G, Surma MA, Rizk S, Grosser D, Lavrynenko O, Rucińska M, Jambor H, Sáenz J. Principles of Membrane Adaptation Revealed through Environmentally Induced Bacterial Lipidome Remodeling. Cell Rep. 2020

Stazi M, Negro S, Megighian A, D'Este G, Solimena M, Jockers R, Lista F, Montecucco C, Rigoni M. Melatonin promotes regeneration of injured motor axons via MT1 receptors. J Pineal Res. 2020

Kaptan D, Penkov S, Zhang X, Gade VR, Raghuraman BK, Galli R, Sampaio JL, Haase R, Koch E, Shevchenko A, Zaburdaev V, Kurzchalia TV. Exogenous ethanol induces a metabolic switch that prolongs the survival of Caenorhabditis elegans dauer larva and enhances its resistance to desiccation. Aging Cell. 2020

Vasiljević J, Torkko JM, Knoch KP, Solimena M. The making of insulin in health and disease. Diabetologia. 2020

Höfner L, Luther AM, Palladini A, Fröhlich T, Waberski D. Tolerance of Stored Boar Spermatozoa to Autologous Seminal Plasma: A Proteomic and Lipidomic Approach. Int J Mol Sci. 2020

Hollstein T, Schulte DM, Schulz J, Glück A, Ziegler AG, Bonifacio E, Wendorff M, Franke A, Schreiber S, Bornstein SR, Laudes M. Autoantibody-negative insulin-dependent diabetes mellitus after SARS-CoV-2 infection: a case report. Nat Metab. 2020

Buitinga M, Cohrs CM, Eter WA, Claessens-Joosten L, Frielink C, Bos D, Sandker G, Brom M, Speier S, Gotthardt M. Non-Invasive Monitoring of Glycemia-Induced Regulation Of GLP-1R Expression in Murine and Human Islets of Langerhans. Diabetes. 2020

Stefanovic S, Laforest B, Desvignes JP, Lescroart F, Argiro L, Maurel-Zaffran C, Salgado D, Plaindoux E, De Bono C, Pazur K, Théveniau-Ruissy M, Béroud C, Puceat M, Gavalas A, Kelly RG, Zaffran S. Hox-dependent coordination of mouse cardiac progenitor cell patterning and differentiation. Elife. 2020

Bornstein SR, Zimmet P, Rubino F, Ludwig B. Management of diabetes in patients with COVID-19 - Authors' reply. Lancet Diabetes Endocrinol. 2020

Bornstein SR, Malyukov M, Heller C, Ziegler CG, Ruiz-Babot G, Schedl A, Ludwig B, Steenblock C. New Horizons: Novel Adrenal Regenerative Therapies. J Clin Endocrinol Metab.

Pinkert S, Pryshliak M, Pappritz K, Knoch K, Hazini A, Dieringer B, Schaar K, Dong F, Hinze L, Lin J, Lassner D, Klopfleisch R, Solimena M, Tschöpe C, Kaya Z, El-Shafeey M, Beling A, Kurreck J, Van Linthout S, Klingel K, Fechner H. Development of a new mouse model for coxsackievirus-induced myocarditis by attenuating coxsackievirus B3 virulence in the pancreas. Cardiovasc Res. 2020

Qadir MMF, Álvarez-Cubela S, Weitz J, Panzer JK, Klein D, Moreno-Hernández Y, Cechin S, Tamayo A, Almaça J, Hiller H, Beery M, Kusmartseva I, Atkinson M, Speier S, Ricordi C, Pugliese A, Caicedo A, Fraker CA, Pastori RL, Domínguez-Bendala J. Publisher Correction: Long-term culture of human pancreatic slices as a model to study real-time islet regeneration. Nat Commun. 2020

Henke C, Töllner K, van Dijk RM, Miljanovic N, Cordes T, Twele F, Bröer S, Ziesak V, Rohde M, Hauck SM, Vogel C, Welzel L, Schumann T, Willmes DM, Kurzbach A, El-Agroudy NN, Bornstein SR, Schneider SA, Jordan J, Potschka H, Metallo CM, Köhling R, Birkenfeld AL, Löscher W. Disruption of the sodium-dependent citrate transporter SLC13A5 in mice causes alterations in brain citrate levels and neuronal network excitability in the hippocampus. Neurobiol Dis. 2020

Pyrina I, Chung KJ, Michailidou Z, Koutsilieris M, Chavakis T, Chatzigeorgiou A. Fate of Adipose Progenitor Cells in Obesity-Related Chronic Inflammation. Front Cell Dev Biol. 2020

Sharma V, Hecker N, Walther F, Stuckas H, Hiller M. Convergent Losses of TLR5 Suggest Altered Extracellular Flagellin Detection in Four Mammalian Lineages. Mol Biol Evol. 2020

Qadir MMF, Álvarez-Cubela S, Weitz J, Panzer JK, Klein D, Moreno-Hernández Y, Cechin S, Tamayo A, Almaça J, Hiller H, Beery M, Kusmartseva I, Atkinson M, Speier S, Ricordi C, Pugliese A, Caicedo A, Fraker CA, Pastori RL, Domínguez-Bendala J. Long-term culture of human pancreatic slices as a model to study real-time islet regeneration. Nat Commun. 2020

Thangapandi VR, Knittelfelder O, Brosch M, Patsenker E, Vvedenskaya O, Buch S, Hinz S, Hendricks A, Nati M, Herrmann A, Rekhade DR, Berg T, Matz-Soja M, Huse K, Klipp E, Pauling JK, Wodke JA, Miranda Ackerman J, Bonin MV, Aigner E, Datz C, von Schönfels W, Nehring S, Zeissig S, Röcken C, Dahl A, Chavakis T, Stickel F, Shevchenko A, Schafmayer C, Hampe J, Subramanian P. Loss of hepatic Mboat7 leads to liver fibrosis. Gut. 2020

Mirea AM, Stienstra R, Kanneganti TD, Tack CJ, Chavakis T, Toonen EJM, Joosten LAB. Mice Deficient in the IL-1β Activation Genes Prtn3, Elane, and Casp1 Are Protected Against the Development of Obesity-Induced NAFLD. Inflammation. 2020

Ziegler AG, Bonifacio E. Why is the presence of autoantibodies against GAD associated with a relatively slow progression to clinical diabetes? Diabetologia. 2020

Carrat GR, Haythorne E, Tomas A, Haataja L, Müller A, Arvan P, Piunti A, Cheng K, Huang M, Pullen TJ, Georgiadou E, Stylianides T, Amirruddin NS, Salem V, Distaso W, Cakebread A, Heesom KJ, Lewis PA, Hodson DJ, Briant LJ, Fung ACH, Sessions RB, Alpy F, Kong APS, Benke PI, Torta F, Teo AKK, Leclerc I, Solimena M, Wigley DB, Rutter GA. The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis. Mol Metab. 2020

Rubino F, Cohen RV, Mingrone G, le Roux CW, Mechanick JI, Arterburn DE, Vidal J, Alberti G, Amiel SA, Batterham RL, Bornstein S, Chamseddine G, Del Prato S, Dixon JB, Eckel RH, Hopkins D, McGowan BM, Pan A, Patel A, Pattou F, Schauer PR, Zimmet PZ, Cummings DE. Bariatric and metabolic surgery during and after the COVID-19 pandemic: DSS recommendations for management of surgical candidates and postoperative patients and prioritisation of access to surgery. Lancet Diabetes Endocrinol. 2020

Kabeza CB, Harst L, Schwarz PEH, Timpel P. A qualitative study of users' experiences after 3 months: the first Rwandan diabetes self-management Smartphone application "Kir'App". Ther Adv Endocrinol Metab. 2020

Bornstein SR, Rubino F, Khunti K, Mingrone G, Hopkins D, Birkenfeld AL, Boehm B, Amiel S, Holt RI, Skyler JS, DeVries JH, Renard E, Eckel RH, Zimmet P, Alberti KG, Vidal J, Geloneze B, Chan JC, Ji L, Ludwig B. Practical recommendations for the management of diabetes in patients with COVID-19. Lancet Diabetes Endocrinol. 2020

Panzer JK, Hiller H, Cohrs CM, Almaça J, Enos SJ, Beery M, Cechin S, Drotar DM, Weitz JR, Santini J, Huber MK, Muhammad Fahd Qadir M, Pastori RL, Domínguez-Bendala J, Phelps EA, Atkinson MA, Pugliese A, Caicedo A, Kusmartseva I, Speier S. Pancreas tissue slices from organ donors enable in situ analysis of type 1 diabetes pathogenesis. JCI Insight. 2020

Timpel P, Lang C, Wens J, Contel JC, Schwarz PEH; MANAGE CARE Study Group. The Manage Care Model - Developing an Evidence-Based and Expert-Driven Chronic Care Management Model for Patients with Diabetes. Int J Integr Care. 2020

Cohrs CM, Panzer JK, Drotar DM, Enos SJ, Kipke N, Chen C, Bozsak R, Schöniger E, Ehehalt F, Distler M, Brennand A, Bornstein SR, Weitz J, Solimena M, Speier S. Dysfunction of Persisting β Cells Is a Key Feature of Early Type 2 Diabetes Pathogenesis. Cell Rep. 2020

Fischer T, Stumpf P, Reinhardt G, Schwarz PEH, Timpel P. Video-based smartphone app ('VIDEA bewegt') for physical activity support in German adults: a study protocol for a single-armed observational study. BMJ Open. 2020

Schuhmacher M, Grasskamp AT, Barahtjan P, Wagner N, Lombardot B, Schuhmacher JS, Sala P, Lohmann A, Henry I, Shevchenko A, Coskun Ü, Walter AM, Nadler A. Live-cell lipid biochemistry reveals a role of diacylglycerol side-chain composition for cellular lipid dynamics and protein affinities. Proc Natl Acad Sci U S A. 2020

Penkov S, Raghuraman BK, Erkut C, Oertel J, Galli R, Ackerman EJM, Vorkel D, Verbavatz JM, Koch E, Fahmy K, Shevchenko A, Kurzchalia TV. A metabolic switch regulates the transition between growth and diapause in C. elegans. BMC Biol. 2020

Timpel P, Oswald S, Schwarz PEH, Harst L. Mapping the Evidence on the Effectiveness of Telemedicine Interventions in Diabetes, Dyslipidemia, and Hypertension: An Umbrella Review of Systematic Reviews and Meta-Analyses. J Med Internet Res. 2020

Willems R, Pil L, Lambrinou CP, Kivelä J, Wikström K, Gonzalez-Gil EM, De Miguel-Etayo P, Nánási A, Semánová C, Van Stappen V, Cardon G, Tsochev K, Iotova V, Chakarova N, Makrilakis K, Dafoulas G, Timpel P, Schwarz P, Manios Y, Annemans L; Feel4Diabetes research group. Methodology of the health economic evaluation of the Feel4Diabetes-study. BMC Endocr Disord. 2020

Kyrou I, Tsigos C, Mavrogianni C, Cardon G, Van Stappen V, Latomme J, Kivelä J, Wikström K, Tsochev K, Nanasi A, Semanova C, Mateo-Gallego R, Lamiquiz-Moneo I, Dafoulas G, Timpel P, Schwarz PEH, Iotova V, Tankova T, Makrilakis K, Manios Y; Feel4Diabetes-study Group. Sociodemographic and lifestyle-related risk factors for identifying vulnerable groups for type 2 diabetes: a narrative review with emphasis on data from Europe. BMC Endocr Disord. 2020

Angelini G, Castagneto Gissey L, Corpo GD, Giordano C, Cerbelli B, Severino A, Manco M, Basso N, Birkenfeld AL, Bornstein SR, Genco A, Mingrone G, Casella G. Publisher Correction: New insight into the mechanisms of ectopic fat deposition improvement after bariatric surgery. Sci Rep. 2020

Mirea AM, Stienstra R, Kanneganti TD, Tack CJ, Chavakis T, Toonen EJM, Joosten LAB. Mice Deficient in the IL-1β Activation Genes Prtn3, Elane, and Casp1 Are Protected Against the Development of Obesity-Induced NAFLD. Inflammation. 2020

Ziegler AG, Kick K, Bonifacio E, Haupt F, Hippich M, Dunstheimer D, Lang M, Laub O, Warncke K, Lange K, Assfalg R, Jolink M, Winkler C, Achenbach P; Fr1da Study Group. Yield of a Public Health Screening of Children for Islet Autoantibodies in Bavaria, Germany. JAMA. 2020

Troullinaki M, Chen LS, Witt A, Pyrina I, Phieler J, Kourtzelis I, Chmelar J, Sprott D, Gercken B, Koutsilieris M, Chavakis T, Chatzigeorgiou A. Robo4-mediated pancreatic endothelial integrity decreases inflammation and islet destruction in autoimmune diabetes. FASEB J. 2020

Gutmann T, Schäfer IB, Poojari C, Brankatschk B, Vattulainen I, Strauss M, Coskun Ü. Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain. J Cell Biol. 2020

Knoop J, Eugster A, Gavrisan A, Lickert R, Sedlmeier EM, Dietz S, Lindner A, Warncke K, Hummel N, Ziegler AG, Bonifacio E. Maternal Type 1 Diabetes Reduces Autoantigen-Responsive CD4+ T Cells in Offspring. Diabetes. 2020

Panzer JK, Cohrs CM, Speier S. Using Pancreas Tissue Slices for the Study of Islet Physiology. Methods Mol Biol. 2020

Singh SP, Ninov N. Multicolor Labeling and Tracing of Pancreatic Beta-Cell Proliferation in Zebrafish. Methods Mol Biol. 2020

Cohrs CM, Chen C, Speier S. Transplantation of Islets of Langerhans into the Anterior Chamber of the Eye for Longitudinal In Vivo Imaging. Methods Mol Biol. 2020

Ludwig B, Wolf E, Schönmann U, Ludwig S. Large Animal Models of Diabetes. Methods Mol Biol. 2020

Schumann T, König J, Henke C, Willmes DM, Bornstein SR, Jordan J, Fromm MF, Birkenfeld AL. Solute Carrier Transporters as Potential Targets for the Treatment of Metabolic Disease. Pharmacol Rev. 2020

Mziaut H, Henniger G, Ganss K, Hempel S, Wolk S, McChord J, Chowdhury K, Ravassard P, Knoch KP, Krautz C, Weitz J, Grützmann R, Pilarsky C, Solimena M, Kersting S. MiR-132 controls pancreatic beta cell proliferation and survival through Pten/Akt/Foxo3 signaling. Mol Metab. 2020

Pryshliak M, Hazini A, Knoch K, Dieringer B, Tolksdorf B, Solimena M, Kurreck J, Pinkert S, Fechner H. MiR-375-mediated suppression of engineered coxsackievirus B3 in pancreatic cells. FEBS Lett. 2020

Kahl S, Gancheva S, Straßburger K, Herder C, Machann J, Katsuyama H, Kabisch S, Henkel E, Kopf S, Lagerpusch M, Kantartzis K, Kupriyanova Y, Markgraf D, van Gemert T, Knebel B, Wolkersdorfer MF, Kuss O, Hwang JH, Bornstein SR, Kasperk C, Stefan N, Pfeiffer A, Birkenfeld AL, Roden M. Empagliflozin Effectively Lowers Liver Fat Content in Well-Controlled Type 2 Diabetes: A Randomized, Double-Blind, Phase 4, Placebo-Controlled Trial. Diabetes Care. 2020

Capristo E, Panunzi S, De Gaetano A, Raffaelli M, Guidone C, Iaconelli A, L'Abbate L, Birkenfeld AL, Bellantone R, Bornstein S, Mingrone G. Corrigendum to "Intensive lifestyle modifications with or without liraglutide 3mg vs. sleeve gastrectomy: A three-arm non-randomised, controlled, pilot study" [Diabetes Metab. 44 (2018) 235-242]. Diabetes Metab. 2020

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Fuchs YF, Sharma V, Eugster A, Kraus G, Morgenstern R, Dahl A, Reinhardt S, Petzold A, Lindner A, Löbel D, Bonifacio E. Gene Expression-Based Identification of Antigen-Responsive CD8(+) T Cells on a Single-Cell Level. Front Immunol. (2019)

Angelini G, Gissey LC, Del Corpo G, Giordano C, Cerbelli B, Severino A, Manco M, Basso N, Birkenfeld AL, Bornstein SR, Genco A, Mingrone G, Casella G. New insight into the mechanisms of ectopic fat deposition improvement after bariatric surgery. Sci Rep. (2019)

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Pinkert S, Pryshliak M, Pappritz K, Knoch K, Hazini A, Dieringer B, Schaar K, Dong F, Hinze L, Lin J, Lassner D, Klopfleisch R, Solimena M, Tschöpe C, Kaya Z, Beling A, Kurreck J, van Linthout S, Klingel K, Fechner H. Development of a New Mouse Model for Coxsackievirus-Induced Myocarditis by Attenuating Coxsackievirus B3 Virulence in the Pancreas. Cardiovasc Res. (2019)

Mameishvili E, Serafimidis I, Iwaszkiewicz S, Lesche M, Reinhardt S, Bölicke N, Büttner M, Stellas D, Papadimitropoulou A, Szabolcs M, Anastassiadis K, Dahl A, Theis F, Efstratiadis A, Gavalas A. Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer. Proc Natl Acad Sci U S A. (2019)

Kabisch S, Meyer NMT, Honsek C, Gerbracht C, Dambeck U, Kemper M, Osterhoff MA, Birkenfeld AL, Arafat AM, Hjorth MF, Weickert MO, Pfeiffer AFH. Fasting Glucose State Determines Metabolic Response to Supplementation with Insoluble Cereal Fibre: A Secondary Analysis of the Optimal Fibre Trial (OptiFiT). Nutrients. (2019)

Binger KJ, Neukam M, Tattikota SG, Qadri F, Puchkov D, Willmes DM, Wurmsee S, Geisberger S, Dechend R, Raile K, Kurth T, Nguyen G, Poy MN, Solimena M, Muller DN, Birkenfeld AL. Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic β cells. Proc Natl Acad Sci U S A. (2019)

Barovic M, Distler M, Schöniger E, Radisch N, Aust D, Weitz J, Ibberson M, Schulte AM, Solimena M. Metabolically phenotyped pancreatectomized patients as living donors for the study of islets in health and diabetes. Mol Metab. (2019)

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Jendle J, Birkenfeld AL, Polonsky WH, Silver R, Uusinarkaus K, Hansen T,
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Straube R, Voit-Bak K, Gor A, Steinmeier T, Chrousos GP, Boehm BO, Birkenfeld
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Schreiber M, Weigelt M, Karasinsky A, Anastassiadis K, Schallenberg S,
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2018

Steenblock C, Rubin de Celis MF, Delgadillo Silva LF, Pawolski V, Brennand A, Werdermann M, Berger I, Santambrogio A, Peitzsch M, Andoniadou CL, Schally AV, Bornstein SR. Isolation and characterization of adrenocortical progenitors involved in the adaptation to stress. Proc Natl Acad Sci U S A. (2018)

Schwarz PEH, Timpel P, Harst L, Greaves CJ, Ali MK, Lambert J, Weber MB, Almedawar MM, Morawietz H. Reprint of: Blood Sugar Regulation for Cardiovascular Health Promotion and Disease Prevention: JACC Health Promotion Series. J Am Coll Cardiol. (2018)

Ashton MP, Eugster A, Dietz S, Loebel D, Lindner A, Kuehn D, Taranko AE, Heschel B, Gavrisan A, Ziegler AG, Aringer M, Bonifacio E. Single-cell profiling reveals dendritic cell signatures associated with autoimmune inflammation. Arthritis Rheumatol. (2018)

Weigert M, Schmidt U, Boothe T, Müller A, Dibrov A, Jain A, Wilhelm B, Schmidt D, Broaddus C, Culley S, Rocha-Martins M, Segovia-Miranda F, Norden C, Henriques R, Zerial M, Solimena M, Rink J, Tomancak P, Royer L, Jug F, Myers EW. Content-aware image restoration: pushing the limits of fluorescence microscopy. Nat Methods. (2018)

Cecon E, Ivanova A, Luka M, Gbahou F, Friederich A, Guillaume JL, Keller P, Knoch K, Ahmad R, Delagrange P, Solimena M, Jockers R. Detection of recombinant and endogenous mouse melatonin receptors by monoclonal antibodies targeting the C-terminal domain. J Pineal Res. (2018)

Singh SP, Janjuha S, Chaudhuri S, Reinhardt S, Kränkel A, Dietz S, Eugster A, Bilgin H, Korkmaz S, Zararsız G, Ninov N, Reid JE. Machine learning based classification of cells into chronological stages using single-cell transcriptomics. Sci Rep. (2018)

Kourtzelis I, Li X, Mitroulis I, Grosser D, Kajikawa T, Wang B, Grzybek M, von Renesse J, Czogalla A, Troullinaki M, Ferreira A, Doreth C, Ruppova K, Chen LS, Hosur K, Lim JH, Chung KJ, Grossklaus S, Tausche AK, Joosten LAB, Moutsopoulos NM, Wielockx B, Castrillo A, Korostoff JM, Coskun Ü, Hajishengallis G, Chavakis T. DEL-1 promotes macrophage efferocytosis and clearance of inflammation. Nat Immunol. (2018)

Dudeck J, Froebel J, Kotrba J, Lehmann CHK, Dudziak D, Speier S, Nedospasov SA, Schraven B, Dudeck A. Engulfment of mast cell secretory granules on skin inflammation boosts dendritic cell migration and priming efficiency. J Allergy Clin Immunol. (2018)

Endesfelder D, Castell WZ, Bonifacio E, Rewers M, Hagopian WA, She JX, Lernmark Å, Toppari J, Vehik K, Williams AJK, Yu L, Akolkar B, Krischer JP, Ziegler AG, Achenbach P; TEDDY Study Group. Time-Resolved Autoantibody Profiling Facilitates Stratification of Preclinical Type 1 Diabetes in Children. Diabetes.(2018)

von Loeffelholz C, Thomas-Rüddel D, Bauer M, Birkenfeld A. Effect of Magnesium Loading Dose on Insulin Resistance in Patients With Stress-Induced Hyperglycemia: A Randomized Clinical Trial. J Intensive Care Med. (2018)

Schwarz PEH, Timpel P, Harst L, Greaves CJ, Ali MK, Lambert J, Weber MB, Almedawar MM, Morawietz H. Blood Sugar Regulation for Cardiovascular Health Promotion and Disease Prevention: JACC Health Promotion Series. J Am Coll Cardiol. (2018)

Capristo E, Panunzi S, De Gaetano A, Spuntarelli V, Bellantone R, Giustacchini P, Birkenfeld AL, Amiel S, Bornstein SR, Raffaelli M, Mingrone G. Response to letter: Incidence of Hypoglycemia After Gastric Bypass vs Sleeve Gastrectomy: A Randomized Trial. J Clin Endocrinol Metab. (2018)

Brankatschk M, Gutmann T, Knittelfelder O, Palladini A, Prince E, Grzybek M, Brankatschk B, Shevchenko A, Coskun Ü, Eaton S. A Temperature-Dependent Switch in Feeding Preference Improves Drosophila Development and Survival in the Cold. Dev Cell. (2018)

Bornstein SR, Steenblock C, Chrousos GP, Schally AV, Beuschlein F, Kline G, Krone NP, Licinio J, Wong ML, Ullmann E, Ruiz-Babot G, Boehm BO, Behrens A, Brennand A, Santambrogio A, Berger I, Werdermann M, Sancho R, Linkermann A, Lenders JW, Eisenhofer G, Andoniadou CL. Stress-inducible-stem cells: a new view on endocrine, metabolic and mental disease? Mol Psychiatry. (2018)

Nieto-Garai JA, Glass B, Bunn C, Giese M, Jennings G, Brankatschk B, Agarwal S, Börner K, Contreras FX, Knölker HJ, Zankl C, Simons K, Schroeder C, Lorizate M, Kräusslich HG. Lipidomimetic Compounds Act as HIV-1 Entry Inhibitors by Altering Viral Membrane Structure. Front Immunol. (2018)

Mathieu C, Lahesmaa R, Bonifacio E, Achenbach P, Tree T. Immunological biomarkers for the development and progression of type 1 diabetes. Diabetologia. (2018)

Holthaus L, Lamp D, Gavrisan A, Sharma V, Ziegler AG, Jastroch M, Bonifacio E. CD4(+) T cell activation, function, and metabolism are inhibited by low concentrations of DMSO. J Immunol Methods. (2018)

Birkenfeld AL, Jordan J, Dworak M, Merkel T, Burnstock G. Myocardial metabolism in heart failure: Purinergic signalling and other metabolic concepts. Pharmacol Ther. (2018)

Tabansky I, Keskin DB, Watts D, Petzold C, Funaro M, Sands W, Wright P, Yunis EJ, Najjar S, Diamond B, Cao Y, Mooney D, Kretschmer K, Stern JNH. Targeting DEC-205(-)DCIR2(+) dendritic cells promotes immunological tolerance in proteolipid protein-induced experimental autoimmune encephalomyelitis. Mol Med. (2018)

Nikolakopoulou P, Chatzigeorgiou A, Kourtzelis I, Toutouna L, Masjkur J, Arps-Forker C, Poser SW, Rozman J, Rathkolb B, Aguilar-Pimentel JA; German Mouse Clinic Consortium, Wolf E, Klingenspor M, Ollert M, Schmidt-Weber C, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Tsata V, Monasor LS, Troullinaki M, Witt A, Anastasiou V, Chrousos G, Yi CX, García-Cáceres C, Tschöp MH, Bornstein SR, Androutsellis-Theotokis A. Streptozotocin-induced β-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain. Sci Rep. (2018)

Selch S, Chafai A, Sticht H, Birkenfeld AL, Fromm MF, König J. Analysis of naturally occurring mutations in the human uptake transporter NaCT important for bone and brain development and energy metabolism. Sci Rep. (2018)

Janjuha S, Pal Singh S, Ninov N. Analysis of Beta-cell Function Using Single-cell Resolution Calcium Imaging in Zebrafish Islets. J Vis Exp. (2018)

Tauscher S, Nakagawa H, Völker K, Werner F, Krebes L, Potapenko T, Doose S, Birkenfeld AL, Baba HA, Kuhn M. β Cell-specific deletion of guanylyl cyclase A, the receptor for atrial natriuretic peptide, accelerates obesity-induced glucose intolerance in mice. Cardiovasc Diabetol. (2018)

Müller D, Telieps T, Eugster A, Weinzierl C, Jolink M, Ziegler AG, Bonifacio E. Novel minor HLA DR associated antigens in type 1 diabetes. Clin Immunol. (2018)

Jordan J, Birkenfeld AL, Melander O, Moro C. Natriuretic Peptides in Cardiovascular and Metabolic Crosstalk: Implications for Hypertension Management. Hypertension. (2018)

Chung KJ, Nati M, Chavakis T, Chatzigeorgiou A. Innate immune cells in the adipose tissue. Rev Endocr Metab Disord. (2018)

von Loeffelholz C, Gissey LC, Schumann T, Henke C, Kurzbach A, Struck J, Bergmann A, Hanefeld M, Schatz U, Bornstein SR, Casella G, Mingrone G, Birkenfeld AL. The anorexigenic peptide neurotensin relates to insulin sensitivity in obese patients after BPD or RYGB metabolic surgery. Int J Obes (Lond). (2018)

Tofte N, Lindhardt M, Adamova K, Beige J, Beulens JWJ, Birkenfeld AL, Currie G, Delles C, Dimos I, Francová L, Frimodt-Møller M, Girman P, Göke R, Havrdova T, Kooy A, Mischak H, Navis G, Nijpels G, Noutsou M, Ortiz A, Parvanova A, Persson F, Ruggenenti PL, Rutters F, Rychlík I, Spasovski G, Speeckaert M, Trillini M, von der Leyen H, Rossing P. Characteristics of high- and low-risk individuals in the PRIORITY study: urinary proteomics and mineralocorticoid receptor antagonism for prevention of diabetic nephropathy in Type 2 diabetes. Diabet Med. (2018)

Hippich M, Oleynik A, Jain K, Winkler C, Ferreira RC, Bonifacio E, Ziegler AG, Briese T. Searching peripheral blood mononuclear cells of children with viral respiratory tract infections preceding islet autoimmunity for viruses by high-throughput sequencing. Acta Diabetol. (2018)

Janjuha S, Singh SP, Tsakmaki A, Mousavy Gharavy SN, Murawala P, Konantz J, Birke S, Hodson DJ, Rutter GA, Bewick GA, Ninov N. Age-related islet inflammation marks the proliferative decline of pancreatic beta-cells in zebrafish. Elife. (2018)

Achenbach P, Hawa MI, Krause S, Lampasona V, Jerram ST, Williams AJK, Bonifacio E, Ziegler AG, Leslie RD; Action LADA consortium. Autoantibodies to N-terminally truncated GAD improve clinical phenotyping of individuals with adult-onset diabetes: Action LADA 12. Diabetologia. (2018)

Schallenberg S, Kretschmer K. New insight into type 1 diabetes development: resolving early diabetogenic CD4(+) T cell responses that precede seroconversion. Ann Transl Med. (2018)

Balyura M, Gelfgat E, Steenblock C, Androutsellis-Theotokis A, Ruiz-Babot G, Guasti L, Werdermann M, Ludwig B, Bornstein T, Schally AV, Brennand A, Bornstein SR. Expression of progenitor markers is associated with the functionality of a bioartificial adrenal cortex. PLoS One. (2018)

Capristo E, Panunzi S, De Gaetano A, Spuntarelli V, Bellantone R, Giustacchini P, Birkenfeld AL, Amiel S, Bornstein SR, Raffaelli M, Mingrone G. Incidence of Hypoglycemia After Gastric Bypass vs Sleeve Gastrectomy: A Randomized Trial. J Clin Endocrinol Metab. (2018)

Gilis-Januszewska A, Barengo NC, Lindström J, Wójtowicz E, Acosta T, Tuomilehto J, Schwarz PEH, Piwońska-Solska B, Szybiński Z, Windak A, Hubalewska-Dydejczyk A. Predictors of long term weight loss maintenance in patients at high risk of type 2 diabetes participating in a lifestyle intervention program in primary health care: The DE-PLAN study. PLoS One. (2018)

Honsek C, Kabisch S, Kemper M, Gerbracht C, Arafat AM, Birkenfeld AL, Dambeck U, Osterhoff MA, Weickert MO, Pfeiffer AFH. Fibre supplementation for the prevention of type 2 diabetes and improvement of glucose metabolism: the randomised controlled Optimal Fibre Trial (OptiFiT). Diabetologia. (2018)

Freudenberg K, Lindner N, Dohnke S, Garbe AI, Schallenberg S, Kretschmer K. Critical Role of TGF-β and IL-2 Receptor Signaling in Foxp3 Induction by an Inhibitor of DNA Methylation. Front Immunol. (2018)

Gutmann T, Kim KH, Grzybek M, Walz T, Coskun Ü. Visualization of ligand-induced transmembrane signaling in the full-length human insulin receptor. J Cell Biol. (2018)

Oshima M, Knoch KP, Diedisheim M, Petzold A, Cattan P, Bugliani M, Marchetti P, Choudhary P, Huang GC, Bornstein SR, Solimena M, Albagli-Curiel O, Scharfmann R. Virus-like infection induces human β cell dedifferentiation. JCI Insight. (2018)

Capristo E, Panunzi S, De Gaetano A, Raffaelli M, Guidone C, Iaconelli A, L'Abbate L, Birkenfeld AL, Bellantone R, Bornstein SR, Mingrone G. Intensive lifestyle modifications with or without liraglutide 3mg vs. sleeve gastrectomy: A three-arm non-randomised, controlled, pilot study. Diabetes Metab. (2018)

Ruiz-Babot G, Balyura M, Hadjidemetriou I, Ajodha SJ, Taylor DR, Ghataore L, Taylor NF, Schubert U, Ziegler CG, Storr HL, Druce MR, Gevers EF, Drake WM, Srirangalingam U, Conway GS, King PJ, Metherell LA, Bornstein SR, Guasti L. Modeling Congenital Adrenal Hyperplasia and Testing Interventions for Adrenal Insufficiency Using Donor-Specific Reprogrammed Cells. Cell Rep. (2018)

Gilis-Januszewska A, Lindström J, Barengo NC, Tuomilehto J, Schwarz PE, Wójtowicz E, Piwońska-Solska B, Szybiński Z, Windak A, Hubalewska-Dydejczyk A. Predictors of completing a primary health care diabetes prevention intervention programme in people at high risk of type 2 diabetes: Experiences of the DE-PLAN project. Medicine (Baltimore). (2018)

Fuchs A, Gliwiński M, Grageda N, Spiering R, Abbas AK, Appel S, Bacchetta R, Battaglia M, Berglund D, Blazar B, Bluestone JA, Bornhäuser M, Ten Brinke A, Brusko TM, Cools N, Cuturi MC, Geissler E, Giannoukakis N, Gołab K, Hafler DA, van Ham SM, Hester J, Hippen K, Di Ianni M, Ilic N, Isaacs J, Issa F, Iwaszkiewicz-Grześ D, Jaeckel E, Joosten I, Klatzmann D, Koenen H, van Kooten C, Korsgren O, Kretschmer K, Levings M, Marek-Trzonkowska NM, Martinez-Llordella M, Miljkovic D, Mills KHG, Miranda JP, Piccirillo CA, Putnam AL, Ritter T, Roncarolo MG, Sakaguchi S, Sánchez-Ramón S, Sawitzki B, Sofronic-Milosavljevic L, Sykes M, Tang Q, Vives-Pi M, Waldmann H, Witkowski P, Wood KJ, Gregori S, Hilkens CMU, Lombardi G, Lord P, Martinez-Caceres EM, Trzonkowski P. Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization. Front Immunol. (2018)

Monzón-Casanova E, Screen M, Díaz-Muñoz MD, Coulson RMR, Bell SE, Lamers G, Solimena M, Smith CWJ, Turner M. The RNA-binding protein PTBP1 is necessary for B cell selection in germinal centers. Nat Immunol. (2018)

Toepfner N, Herold C, Otto O, Rosendahl P, Jacobi A, Kräter M, Stächele J, Menschner L, Herbig M, Ciuffreda L, Ranford-Cartwright L, Grzybek M, Coskun Ü, Reithuber E, Garriss G, Mellroth P, Henriques-Normark B, Tregay N, Suttorp M, Bornhäuser M, Chilvers ER, Berner R, Guck J. Detection of human disease conditions by single-cell morpho-rheological phenotyping of blood. Elife. (2018)

Mitroulis I, Ruppova K, Wang B, Chen LS, Grzybek M, Grinenko T, Eugster A, Troullinaki M, Palladini A, Kourtzelis I, Chatzigeorgiou A, Schlitzer A, Beyer M, Joosten LAB, Isermann B, Lesche M, Petzold A, Simons K, Henry I, Dahl A, Schultze JL, Wielockx B, Zamboni N, Mirtschink P, Coskun Ü, Hajishengallis G, Netea MG, Chavakis T. Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity. Cell. (2018)

Solimena M, Schulte AM, Marselli L, Ehehalt F, Richter D, Kleeberg M, Mziaut H, Knoch KP, Parnis J, Bugliani M, Siddiq A, Jörns A, Burdet F, Liechti R, Suleiman M, Margerie D, Syed F, Distler M, Grützmann R, Petretto E, Moreno-Moral A, Wegbrod C, Sönmez A, Pfriem K, Friedrich A, Meinel J, Wollheim CB, Baretton GB, Scharfmann R, Nogoceke E, Bonifacio E, Sturm D, Meyer-Puttlitz B, Boggi U, Saeger HD, Filipponi F, Lesche M, Meda P, Dahl A, Wigger L, Xenarios I, Falchi M, Thorens B, Weitz J, Bokvist K, Lenzen S, Rutter GA, Froguel P, von Bülow M, Ibberson M, Marchetti P. Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes. Diabetologia. (2018)

Balyura M, Gelfgat E, Ullmann E, Ludwig B, Barnea ER, Bornstein SR. PreImplantation Factor (PIF*) Regulates Stress-Induced Adrenal Steroidogenesis and Anti-Inflammatory Cytokines: Potential Application for Bioartificial Adrenal Transplant. Horm Metab Res. (2018)

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Willmes DM, Kurzbach A, Henke C, Schumann T, Zahn G, Heifetz A, Jordan J, Helfand SL, Birkenfeld AL. The longevity gene INDY (I'm Not Dead Yet) in metabolic control: Potential as pharmacological target. Pharmacol Ther. (2018)

Weitz JR, Makhmutova M, Almaça J, Stertmann J, Aamodt K, Brissova M, Speier S, Rodriguez-Diaz R, Caicedo A. Mouse pancreatic islet macrophages use locally released ATP to monitor beta cell activity. Diabetologia. (2018)

von Loeffelholz C, Birkenfeld A. The Role of Non-exercise Activity Thermogenesis in Human Obesity. In: De Groot LJ et al. Endotext (2018)

2017

Alfar, E.A. ; Kirova, D. ; Konantz, J. ; Birke, S. ; Mansfeld, J. ; Ninov, N. Distinct levels of reactive oxygen species coordinate metabolic activity with beta-cell mass plasticity. Sci. Rep. 7 (2017)

Anitei, M. ; Stange, C. ; Czupalla, C. ; Niehage, C. ; Schuhmann, K. ; Sala, P. ; Czogalla, A. ; Pursche, T. ; Coskun, Ü. ; Shevchenko, A. ; Hoflack, B. Spatiotemporal control of lipid conversion, actin-based mechanical forces, and curvature sensors during clathrin/AP-1-coated vesicle biogenesis. Cell Rep. 20, 2087-2099 (2017)

Bilkova, E. ; Pleskot, R. ; Rissanen, S. ; Sun, S. ; Czogalla, A. ; Cwiklik, L. ; Róg, T. ; Vattulainen, I. ; Cremer, P.S. ; Jungwirth, P. ; Coskun, Ü. Calcium directly regulates phosphatidylinositol 4,5-Bbsphosphate headgroup conformation and recognition. J. Am. Chem. Soc. 139, 4019-4024 (2017)

Blutke, A. ; Renner, S. ; Flenkenthaler, F. ; Backman, M. ; Haesner, S. ; Kemter, E. ; Ländström, E. ; Braun-Reichhart, C. ; Albl, B. ; Streckel, E. ; Rathkolb, B. ; Prehn, C. ; Palladini, A. ; Grzybek, M. ; Krebs, S. ; Bauersachs, S. ; Bähr, A. ; Brühschwein, A. ; Deeg, C.A. ; De Monte, E. ; Dmochewitz, M. ; Eberle, C. ; Emrich, D. ; Fux, R. ; Groth, F. ; Gumbert, S. ; Heitmann, A. ; Hinrichs, A.S. ; Keßler, B. ; Kurome, M. ; Leipig-Rudolph, M. ; Matiasek, K. ; Öztürk, H. ; Otzdorff, C. ; Reichenbach, M. ; Reichenbach, H.D. ; Rieger, A. ; Rieseberg, B. ; Rosati, M. ; Saucedo, M.N. ; Schleicher, A. ; Schneider, M.R. ; Simmet, K. ; Steinmetz, J. ; Übel, N. ; Zehetmaier, P. ; Jung, A. ; Adamski, J. ; Coskun, Ü. ; Hrabě de Angelis, M. ; Simmet, C. ; Ritzmann, M. ; Meyer-Lindenberg, A. ; Blum, H. ; Arnold, G.J. ; Fröhlich, T. ; Wanke, R. ; Wolf, E. The Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes. Mol. Metab. 6, 931-940 (2017)

Brunssen, C. ; Hofmann, A. ; Peitzsch, M. ; Frenzel, A. ; Ziegler, C.G. ; Brown, N.F. ; Weldon, S.M. ; Eisenhofer, G. ; Willenberg, H.S. ; Bornstein, S.R. ; Morawietz, H. Impact of aldosterone synthase inhibitor FAD286 on steroid hormone profile in human adrenocortical cells. Horm. Metab. Res. 49, 701-706 (2017)

Carrat, G.R. ; Hu, M. ; Nguyen-Tu, M. ; Chabosseau, P. ; Gaulton, K.J. ; van de Bunt, M. ; Siddiq, A. ; Falchi, M. ; Thurner, M. ; Canouil, M. ; Pattou, F. ; Leclerc, I. ; Pullen, T.J. ; Cane, M.C. ; Prabhala, P. ; Greenwald, W. ; Schulte, A. ; Marchetti, P. ; Ibberson, M. ; MacDonald, P.E. ; Fox, J.E.M. ; Gloyn, A.L. ; Froguel, P. ; Solimena, M. ; McCarthy, M.I. ; Rutter, G.A. Decreased STARD10 expression is associated with defective insulin secretion in humans and mice. Am. J. Hum. Genet. 100, 238-256 (2017)

Chen, C. ; Cohrs, C.M. ; Stertmann, J. ; Bozsak, R. ; Speier, S. Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis. Mol. Metab. (2017)

Chung, K.-J. ; Chatzigeorgiou, A. ; Economopoulou, M. ; Garcia-Martin, R. ; Alexaki, V.I. ; Mitroulis, I. ; Nati, M. ; Gebler, J. ; Ziemssen, T. ; Goelz, S.E. ; Phieler, J. ; Lim, J.H. ; Karalis, K.P. ; Papayannopoulou, T. ; Blueher, M. ; Hajishengallis, G. ; Chavakis, T. A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity. Nat. Immunol. 18, 654-664 (2017)

Cohrs, C.M. ; Chen, C. ; Jahn, S. ; Stertmann, J. ; Chmelova, H. ; Weitz, J. ; Bähr, A. ; Klymiuk, N. ; Steffen, A. ; Ludwig, B. ; Kamvissi, V. ; Wolf, E. ; Bornstein, S.R. ; Solimena, M. ; Speier, S. Vessel network architecture of adult human islets promotes distinct cell-cell interactions in situ and is altered after transplantation. Endocrinology 158, 1-13 (2017)

Dudeck, J. ; Medyukhina, A. ; Fröbel, J. ; Svensson, C.M. ; Kotrba, J. ; Gerlach, M. ; Gradtke, A.C. ; Schröder, B. ; Speier, S. ; Figge, M.T. ; Dudeck, A. Mast cells acquire MHC II from dendritic cells during skin inflammation. J. Exp. Med. 214, 3791-3811 (2017)

Fuchs, Y.F. ; Eugster, A. ; Dietz, S. ; Sebelefsky, C. ; Kühn, D. ; Wilhelm, C. ; Lindner, A. ; Gavrisan, A. ; Knoop, J. ; Dahl, A. ; Ziegler, A.-G. ; Bonifacio, E. CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage. Sci. Rep. 7:44661 (2017)

Hanefeld, M. ; Engelmann, K. ; Appelt, D. ; Sandner, D. ; Weigmann, I. ; Ganz, X. ; Pistrosch, F. ; Koehler, C.M. ; Gasparic, A. ; Birkenfeld, A.L. Intra-individual variability and circadian rhythm of vascular endothelial growth factors in subjects with normal glucose tolerance and type 2 diabetes. PLoS ONE 12:e0184234 (2017)

Heidenreich, S. ; Witte, N. ; Weber, P. ; Goehring, I. ; Tolkachov, A. ; von Loeffelholz, C. ; Doecke, S. ; Bauer, M. ; Stockmann, M. ; Pfeiffer, A.F.H. ; Birkenfeld, A.L. ; Pietzke, M. ; Kempa, S. ; Muenzner, M. ; Schupp, M. Retinol saturase coordinates liver metabolism by regulating ChREBP activity. Nat. Commun. 8:384 (2017)

Kamel, M. ; Ninov, N. Catching new targets in metabolic disease with a zebrafish. Curr. Opin. Pharmacol. 37, 41-50 (2017)

Ludwig, B. ; Ludwig, S. ; Steffen, A. ; Knauf, Y. ; Zimerman, B. ; Heinke, S. ; Lehmann, S. ; Schubert, U. ; Schmid, J. ; Bleyer, M. ; Schoenmann, U. ; Colton, C.K. ; Bonifacio, E. ; Solimena, M. ; Reichel, A. ; Schally, A.V. ; Rotem, A. ; Barkai, U. ; Grinberg-Rashi, H. ; Kaup, F. ; Avni, Y. ; Jones, P. ; Bornstein, S.R. Favorable outcome of experimental islet xenotransplantation without immunosuppression in a nonhuman primate model of diabetes. Proc. Natl. Acad. Sci. U.S.A. 114, 11745-11750 (2017)

Müller, A. ; Neukam, M. ; Ivanova, A. ; Sönmez, A. ; Münster, C. ; Kretschmar, S. ; Kalaidzidis, Y. ; Kurth, T. ; Verbavatz, J.-M. ; Solimena, M. A global approach for quantitative super resolution and electron microscopy on cryo and epoxy sections using self-labeling protein tags. Sci. Rep. 7:23 (2017)

Müller, A. ; Mziaut, H. ; Neukam, M. ; Knoch, K.-P. ; Solimena, M. A 4D view on insulin secretory granule turnover in the β-cell. Diabetes Obes. Metab. 19, 107-114 (2017)

Rathjen, T. ; Yan, X. ; Kononenko, N.L. ; Ku, M.C. ; Song, K. ; Ferrarese, L. ; Tarallo, V. ; Puchkov, D. ; Kochlamazashvili, G. ; Brachs, S. ; Varela, L. ; Szigeti-Buck, K. ; Yi, C.-X. ; Schriever, S.C. ; Tattikota, S.G. ; Carlo, A.S. ; Moroni, M. ; Siemens, J. ; Heuser, A. ; van der Weyden, L. ; Birkenfeld, A.L. ; Niendorf, T. ; Poulet, J.F.A. ; Horvath, T.L. ; Tschöp, M. ; Heinig, M. ; Trajkovski, M. ; Haucke, V. ; Poy, M.N. Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1. Nat. Neurosci. 20, 1096-1103 (2017)

Rissanen, S. ; Grzybek, M. ; Orlowski, A. ; Róg, T. ; Cramariuc, O. ; Levental, I. ; Eggeling, C. ; Sezgin, E. ; Vattulainen, I. Phase partitioning of GM1 and its bodipy-labeled analog determine their different binding to Cholera Toxin. Front. Physiol. 8:252 (2017)

Schuhmann, K. ; Srzentić, K. ; Nagornov, K.O. ; Thomas, H. ; Gutmann, T. ; Coskun, Ü. ; Tsybin, Y.O. ; Shevchenko, A. Monitoring membrane lipidome turnover by metabolic15N labeling and shotgun ultra-high-resolution orbitrap fourier transform mass spectrometry. Anal. Chem. 89, 12857-12865 (2017)

Serafimidis, I. ; Rodriguez-Aznar, E. ; Lesche, M. ; Yoshioka, K. ; Takuwa, Y. ; Dahl, A. ; Pan, D. ; Gavalas, A. Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling. PLoS Biol. 15:e2000949 (2017)

Singh, S.P. ; Janjuha, S. ; Hartmann, T. ; Kayisoglu, O. ; Konantz, J. ; Birke, S. ; Murawala, P. ; Alfar, E.A. ; Murata, K. ; Eugster, A. ; Tsuji, N. ; Morrissey, E.R. ; Brand, M. ; Ninov, N. Different developmental histories of beta-cells generate functional and proliferative heterogeneity during islet growth. Nat. Commun. 8:664 (2017)

Solimena, M. ; Schulte, A.M. ; Marselli, L. ; Ehehalt, F. ; Richter, D. ; Kleeberg, M. ; Mziaut, H. ; Knoch, K.-P. ; Parnis, J. ; Bugliani, M. ; Siddiq, A. ; Jörns, A. ; Burdet, F. ; Liechti, R. ; Suleiman, M. ; Margerie, D. ; Syed, F. ; Distler, M. ; Grützmann, R. ; Petretto, E. ; Moreno-Moral, A. ; Wegbrod, C. ; Sönmez, A. ; Pfriem, K. ; Friedrich, A. ; Meinel, J. ; Wollheim, C.B. ; Baretton, G.B. ; Scharfmann, R. ; Nogoceke, E. ; Bonifacio, E. ; Sturm, D. ; Meyer-Puttlitz, B. ; Boggi, U. ; Saeger, H.-D. ; Filipponi, F. ; Lesche, M. ; Meda, P. ; Dahl, A. ; Wigger, L. ; Xenarios, I. ; Falchi, M. ; Thorens, B. ; Weitz, J. ; Bokvist, K. ; Lenzen, S. ; Rutter, G.A. ; Froguel, P. ; von Bülow, M. ; Ibberson, M. ; Marchetti, P. Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes. Diabetologia, 1-17 (2017)

Stefanko, A. ; Thiede, C. ; Ehninger, G. ; Simons, K. ; Grzybek, M. Lipidomic approach for stratification of acute myeloid leukemia patients. PLoS ONE 12:e0168781 (2017)

Steffen, A. ; Kiss, T. ; Schmid, J. ; Schubert, U. ; Heinke, S. ; Lehmann, S. ; Bornstein, S.R. ; Ludwig, B. ; Ludwig, S. Production of high-quality islets from goettingen minipigs: Choice of organ preservation solution, donor pool, and optimal cold ischemia time. Xenotransplantation 24:e12284 (2017)

Steringer, J.P. ; Lange, S. ; Čujová, S. ; Šachl, R. ; Poojari, C. ; Lolicato, F. ; Beutel, O. ; Müller, H.M. ; Unger, S. ; Coskun, Ü. ; Honigmann, A. ; Vattulainen, I. ; Hof, M. ; Freund, C. ; Nickel, W. Key steps in unconventional secretion of fibroblast growth factor 2 reconstituted with purified components. eLife 6:e28985 (2017)

von Bibra, H. ; Saha, S. ; Hapfelmeier, A. ; Mueller, G. ; Schwarz, P.E. Impact of the triglyceride/high-density lipoprotein cholesterol ratio and the hypertriglyceremic-waist phenotype to predict the metabolic syndrome and insulin resistance. Horm. Metab. Res. 49, 542-549 (2017)

von Loeffelholz, C. ; Lieske, S. ; Neuschäfer-Rube, F. ; Willmes, D.M. ; Raschzok, N. ; Sauer, I.M. ; König, J. ; Fromm, M. ; Horn, P. ; Chatzigeorgiou, A. ; Pathe-Neuschäfer-Rube, A. ; Jordan, J. ; Pfeiffer, A.F.H. ; Mingrone, G. ; Bornstein, S.R. ; Ströhle, P. ; Harms, C. ; Wunderlich, F.T. ; Helfand, S.L. ; Bernier, M. ; de Cabo, R. ; Shulman, G.I. ; Chavakis, T. ; Püschel, G.P. ; Birkenfeld, A.L. The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism. Hepatology 66, 616-630 (2017)

Weitz, J.R. ; Makhmutova, M. ; Almaça, J. ; Stertmann, J. ; Aamodt, K. ; Brissova, M. ; Speier, S. ; Rodriguez-Diaz, R. ; Caicedo, A. Mouse pancreatic islet macrophages use locally released ATP to monitor beta cell activity. Diabetologia 61, 1-11 (2017)

Willmes, D.M. ; Kurzbach, A. ; Henke, C. ; Zahn, G. ; Heifetz, A. ; Jordan, J. ; Helfand, S.L. ; Birkenfeld, A.L. The longevity gene INDY (I'm Not Dead Yet) in metabolic control: Potential as pharmacological target. Pharmacol. Ther., DOI: 10.1016/j.pharmthera.2017.10.003 (2017)

2016

Alexaki, V.I. ; Chavakis, T. The role of innate immunity in the regulation of brown and beige adipogenesis. Rev. Endocr. Metab. Disord. 17, 41-49 (2016)

Anastasiou, V. ; Ninou, E. ; Alexopoulou, D. ; Stertmann, J. ; Müller, A. ; Dahl, A. ; Solimena, M. ; Speier, S. ; Serafimidis, I. ; Gavalas, A. Aldehyde dehydrogenase activity is necessary for beta cell development and functionality in mice. Diabetologia 59, 139-150 (2016)

Bader, E. ; Migliorini, A. ; Gegg, M. ; Moruzzi, N. ; Gerdes, J.M. ; Roscioni, S. ; Bakhti, M. ; Brandl, E. ; Irmler, M. ; Beckers, J. ; Aichler, M. ; Feuchtinger, A. ; Leitzinger, C. ; Zischka, H. ; Wang-Sattler, R. ; Jastroch, M. ; Tschöp, M. ; Machicao, F. ; Staiger, H. ; Häring, H.-U. ; Chmelova, H. ; Chouinard, J.A. ; Oskolkov, N. ; Korsgren, O. ; Speier, S. ; Lickert, H. Identification of proliferative and mature β-cells in the islets of Langerhans. Nature 535, 430-434 (2016)

Catani, M. ; Walther, D. ; Christie, M.R. ; McLaughlin, K.A. ; Bonifacio, E. ; Eugster, A. Isolation of human monoclonal autoantibodies derived from pancreatic lymph node and peripheral blood B cells of islet autoantibody-positive patients. Diabetologia 59, 294-298 (2016)

Chen, C. ; Chmelova, H. ; Cohrs, C.M. ; Chouinard, J.A. ; Jahn, S. ; Stertmann, J. ; Uphues, I. ; Speier, S. Alterations in β-cell calcium dynamics and efficacy outweigh islet mass adaptation in compensation of insulin resistance and prediabetes onset. Diabetes 65, 2676-2685 (2016)

Chmelar, J. ; Chatzigeorgiou, A. ; Chung, K.-J. ; Prucnal, M. ; Voehringer, D. ; Roers, A. ; Chavakis, T. No role for mast cells in obesity-related metabolic dysregulation. Front. Immunol. 7:524 (2016)

Daniels, M.A. ; Kan, C. ; Willmes, D.M. ; Ismail, K. ; Pistrosch, F. ; Hopkins, D. ; Mingrone, G. ; Bornstein, S.R. ; Birkenfeld, A.L. Pharmacogenomics in type 2 diabetes: Oral antidiabetic drugs. Pharmacogenomics J. 16, 399-410 (2016)

Ehret, G.B. ; Ferreira, T. ; Chasman, D.I. ; Jackson, A.U. ; Schmidt, E.M. ; Johnson, T. ; Thorleifsson, G. ; Luan, J. ; Donnelly, L.A. ; Kanoni, S. ; Petersen, A.-K. ; Pihur, V. ; Strawbridge, R.J. ; Shungin, D. ; Hughes, M.F. ; Meirelles, O. ; Kaakinen, M. ; Bouatia-Naji, N. ; Kristiansson, K. ; Shah, S. ; Kleber, M.E. ; Guo, X. ; Lyytikäinen, L.P. ; Fava, C. ; Eriksson, N. ; Nolte, I.M. ; Magnusson, P.K. ; Salfati, E.L. ; Rallidis, L.S. ; Theusch, E. ; Smith, A.J. ; Folkersen, L. ; Witkowska, K. ; Pers, T.H. ; Joehanes, R. ; Kim, S.K. ; Lataniotis, L. ; Jansen, R. ; Johnson, A.D. ; Warren, H. ; Kim, Y.J. ; Zhao, W. ; Wu, Y. ; Tayo, B.O. ; Bochud, M. ; Absher, D. ; Adair, L.S. ; Amin, N. ; Arking, D.E. ; Axelsson, T. ; Baldassarre, D. ; Balkau, B. ; Bandinelli, S. ; Barnes, M.R. ; Barroso, I. ; Bevan, S. ; Bis, J.C. ; Bjornsdottir, G. ; Boehnke, M. ; Boerwinkle, E. ; Bonnycastle, L.L. ; Boomsma, D.I. ; Bornstein, S. ; Brown, M.J. ; Burnier, M. ; Cabrera, C.P. ; Chambers, J.C. ; Chang, I.S. ; Cheng, C.Y. ; Chines, P.S. ; Chung, R.H. ; Collins, F.S. ; Connell, J.M. ; Döring, A. ; Dallongeville, J. ; Danesh, J. ; de Faire, U. ; Delgado, G. ; Dominiczak, A.F. ; Doney, A.S. ; Drenos, F. ; Edkins, S. ; Eicher, J.D. ; Elosua, R. ; Enroth, S. ; Erdmann, J. ; Eriksson, P. ; Esko, T. ; Evangelou, E. ; Evans, A. ; Fall, T. ; Farrall, M. ; Felix, J.F. ; Ferrieres, J. ; Ferrucci, L. ; Fornage, M. ; Forrester, T. ; Franceschini, N. ; Franco, O.H. ; Franco-Cereceda, A. ; Fraser, R.M. ; Ganesh, S.K. ; Gao, H. ; Gertow, K. ; Gianfagna, F. ; Gigante, B. ; Giulianini, F. ; Goel, A. ; Goodall, A.H. ; Goodarzi, M.O. ; Gorski, M. ; Gräßler, J. ; Groves, C.J. ; Gudnason, V. ; Gyllensten, U. ; Hallmans, G. ; Hartikainen, A.L. ; Hassinen, M. ; Havulinna, A.S. ; Hayward, C. ; Hercberg, S. ; Herzig, K.H. ; Hicks, A.A. ; Hingorani, A.D. ; Hirschhorn, J.N. ; Hofman, A. ; Holmen, J. ; Holmen, O.L. ; Hottenga, J.J. ; Howard, P. ; Hsiung, C.A. ; Hunt, S.C. ; Ikram, M.A. ; Illig, T. ; Iribarren, C. ; Jensen, R.A. ; Kähönen, M. ; Kang, H.M. ; Kathiresan, S. ; Keating, B.J. ; Khaw, K.T. ; Kim, Y.K. ; Kim, E. ; Kivimaki, M. ; Klopp, N. ; Kolovou, G. ; Komulainen, P. ; Kooner, J.S. ; Kosova, G. ; Krauss, R.M. ; Kuh, D. ; Kutalik, Z. ; Kuusisto, J. ; Kvaløy, K. ; Lakka, T.A. ; Lee, N.R. ; Lee, I.T. ; Lee, W.J. ; Levy, D. ; Li, X. ; Liang, K.W. ; Lin, H. ; Lin, L. ; Lindstrom, J. ; Lobbens, S. ; Männisto, S. ; Müller, G. ; Müller-Nurasyid, M. ; Mach, F. ; Markus, H.S. ; Marouli, E. ; McCarthy, M.I. ; McKenzie, C.A. ; Meneton, P. ; Menni, C. ; Metspalu, A. ; Mijatovic, V. ; Moilanen, L. ; Montasser, M.E. ; Morris, A.D. ; Morrison, A.C. ; Mulas, A. ; Nagaraja, R. ; Narisu, N. ; Nikus, K. ; O'Donnell, C.J. ; O'Reilly, P.F. ; Ong, K.K. ; Paccaud, F. ; Palmer, C.D. ; Parsa, A. ; Pedersen, N.L. ; Penninx, B.W. ; Perola, M. ; Peters, A. ; Poulter, N. ; Pramstaller, P.P. ; Psaty, B.M. ; Quertermous, T. ; Rao, D.C. ; Rasheed, A. ; Rayner, N.W. ; Renström, F. ; Rettig, R. ; Rice, K.M. ; Roberts, R. ; Rose, L.M. ; Rossouw, J. ; Samani, N.J. ; Sanna, S. ; Saramies, J. ; Schunkert, H. ; Sebert, S. ; Sheu, W.H. ; Shin, Y.A. ; Sim, X. ; Smit, J.H. ; Smith, A.V. ; Sosa, M.X. ; Spector, T.D. ; Stancáková, A. ; Stanton, A.V. ; Stirrups, K.E. ; Stringham, H.M. ; Sundström, J. ; Swift, A.J. ; Syvanen, A.C. ; Tai, E.S. ; Tanaka, T. ; Tarasov, K.V. ; Teumer, A. ; Thorsteinsdottir, U. ; Tobin, M.D. ; Tremoli, E. ; Uitterlinden, A.G. ; Uusitupa, M. ; Vaez, A. ; Vaidya, D. ; van Duijn, C.M. ; van Iperen, E.P. ; Vasan, R.S. ; Verwoert, G.C. ; Virtamo, J. ; Vitart, V. ; Voight, B.F. ; Vollenweider, P. ; Wagner, A. ; Wain, L.V. ; Wareham, N.J. ; Watkins, H. ; Weder, A.B. ; Westra, H.J. ; Wilks, R.J. ; Wilsgaard, T. ; Wilson, J.F. ; Wong, T.Y. ; Yang, T.P. ; Yao, J. ; Yengo, L. ; Zhang, W. ; Zhao, J.H. ; Zhu, X. ; Bovet, P. ; Cooper, R.S. ; Mohlke, K.L. ; Saleheen, D. ; Lee, J.Y. ; Elliott, P. ; Gierman, H.J. ; Willer, C.J. ; Franke, L. ; Hovingh, G.K. ; Taylor, K.D. ; Dedoussis, G. ; Sever, P. ; Wong, A. ; Lind, L. ; Assimes, T.L. ; Njølstad, I. ; Schwarz, P.E.H. ; Langenberg, C. ; Snieder, H. ; Caulfield, M.J. ; Melander, O. ; Laakso, M. ; Saltevo, J. ; Rauramaa, R. ; Tuomilehto, J. ; Ingelsson, E. ; Lehtimäki, T. ; Hveem, K. ; Palmas, W. ; Marz, W. ; Kumari, M. ; Salomaa, V. ; Chen, Y.I. ; Rotter, J.I. ; Froguel, P. ; Jarvelin, M.R. ; Lakatta, E.G. ; Kuulasmaa, K. ; Franks, P.W. ; Hamsten, A. ; CHARGE-EchoGen Consortium (Wichmann, H.-E. ; Meitinger, T.) ; Palmer, C.N. ; Stefansson, K. ; Ridker, P.M. ; Loos, R.J. ; Chakravarti, A. ; Deloukas, P. ; Morris, A.P. ; Newton-Cheh, C. ; Munroe, P.B. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nat. Genet. 48, 1171-1184 (2016)

Garcia-Martin, R. ; Alexaki, V.I. ; Qin, N. ; Rubin de Celis, M.F. ; Economopoulou, M. ; Ziogas, A. ; Gercken, B. ; Kotlabova, K. ; Phieler, J. ; Ehrhart-Bornstein, M. ; Bornstein, S.R. ; Eisenhofer, G. ; Breier, G. ; Blueher, M. ; Hampe, J. ; El-Armouche, A. ; Chatzigeorgiou, A. ; Chung, K.-J. ; Chavakis, T. Adipocyte-specific hypoxia-inducible factor 2α deficiency exacerbates obesity-induced brown adipose tissue dysfunction and metabolic dysregulation. Mol. Cell. Biol. 36, 376-393 (2016)

Gruetzmann, R. ; Ludwig, B. ; Weitz, J. ; Ludwig, S. Totale Pankreatektomie und Isletautotransplantation bei einem Kind mit chronisch rezidivierender Pankreatitis. Zentralbl. Chir. 141, 17-20 (2016)

Hanefeld, M. ; Pistrosch, F. ; Bornstein, S.R. ; Birkenfeld, A.L. The metabolic vascular syndrome - guide to an individualized treatment. Rev. Endocr. Metab. Disord. 17, 5-17 (2016)

Heinke, S. ; Ludwig, B. ; Schubert, U. ; Schmid, J. ; Kiss, T. ; Steffen, A. ; Bornstein, S.R. ; Ludwig, S. Diabetes induction by total pancreatectomy in minipigs with simultaneous splenectomy: A feasible approach for advanced diabetes research. Xenotransplantation 23, 405-413 (2016)

Klose, C. ; Coskun, Ü. Shotgun Lipidomics in der biomedizinischen und klinischen Forschung: Hochdurchsatzscreening. BIOspektrum 22, 617-619 (2016)

Kourtzelis, I. ; Kotlabova, K. ; Lim, J.H. ; Mitroulis, I. ; Ferreira, A. ; Chen, L. ; Gercken, B. ; Steffen, A. ; Kemter, E. ; Klotzsche-von Ameln, A. ; Waskow, C. ; Hosur, K. ; Chatzigeorgiou, A. ; Ludwig, B. ; Wolf, E. ; Hajishengallis, G. ; Chavakis, T. Developmental endothelial locus-1 modulates platelet-monocyte interactions and instant blood-mediated inflammatory reaction in islet transplantation. Thromb. Haemost. 115, 781-788 (2016)

Kragl, M. ; Schubert, R. ; Karsjens, H. ; Otter, S. ; Bartosinska, B. ; Jeruschke, K. ; Weiss, J. ; Chen, C. ; Alsteens, D. ; Kuss, O. ; Speier, S. ; Eberhard, D. ; Müller, D.J. ; Lammert, E. The biomechanical properties of an epithelial tissue determine the location of its vasculature. Nat. Commun. 7:13560 (2016)

Liikanen, I. ; Tahtinen, S. ; Guse, K. ; Gutmann, T. ; Savola, P. ; Oksanen, M. ; Kanerva, A. ; Hemminki, A. Oncolytic adenovirus expressing monoclonal antibody trastuzumab for treatment of HER2-positive cancer. Mol. Cancer Ther. 15, 2259-2269 (2016)

Markmann, J.F. ; Bartlett, S.T. ; Johnson, P. ; Korsgren, O. ; Hering, B.J. ; Scharp, D. ; Kay, T.W. ; Bromberg, J. ; Odorico, J.S. ; Weir, G.C. ; Bridges, N.D. ; Kandaswamy, R. ; Stock, P. ; Friend, P. ; Gotoh, M. ; Cooper, D.K. ; Park, C.G. ; OʼConnell, P.J. ; Stäbler, C. ; Matsumoto, S. ; Ludwig, B. ; Choudhary, P. ; Khovatchev, B. ; Rickels, M.R. ; Sykes, M. ; Wood, K. ; Kraemer, K. ; Hwa, A. ; Stanley, E. ; Ricordi, C. ; Zimmerman, M. ; Greenstein, J. ; Montanya, E. ; Otonkoski, T. Executive summary of IPITA-TTS opinion leaders report on the future of β-cell replacement. Transplantation 100, E25-E31 (2016)

Morozov, V.A. ; Ludwig, S. ; Ludwig, B. ; Rotem, A. ; Barkai, U. ; Bornstein, S.R. ; Denner, J. Islet cell transplantation from Gottingen minipigs to cynomolgus monkeys: Analysis of virus safety. Xenotransplantation 23, 320-327 (2016)

Mziaut, H. ; Mulligan, B. ; Hoboth, P. ; Otto, O. ; Ivanova, A. ; Herbig, M. ; Schumann, D. ; Hildebrandt, T.B. ; Dehghany, J. ; Sönmez, A. ; Münster, C. ; Meyer-Hermann, M. ; Guck, J. ; Kalaidzidis, Y. ; Solimena, M. The F-actin modifier villin regulates insulin granule dynamics and exocytosis downstream of islet cell autoantigen 512. Mol. Metab. 5, 656-68 (2016)

Nati, M. ; Haddad, D. ; Birkenfeld, A.L. ; Koch, C.A. ; Chavakis, T. ; Chatzigeorgiou, A. The role of immune cells in metabolism-related liver inflammation and development of Non-Alcoholic Steatohepatitis (NASH). Rev. Endocr. Metab. Disord. 17, 29-39 (2016)

Raab, J. ; Haupt, F. ; Scholz, M. ; Matzke, C. ; Warncke, K. ; Lange, K. ; Assfalg, R. ; Weininger, K. ; Wittich, S. ; Löbner, S. ; Beyerlein, A. ; Nennstiel-Ratzel, U. ; Lang, M. ; Laub, O. ; Dunstheimer, D. ; Bonifacio, E. ; Achenbach, P. ; Winkler, C. ; Ziegler, A.-G. Capillary blood islet autoantibody screening for identifying pre-type 1 diabetes in the general population: Design and initial results of the Fr1da study. BMJ Open 6:e011144 (2016)

Richter, K. ; Barthel, A. ; Bornstein, S.R. ; El-Armouche, A. ; Wagner, M. PCSK9-Inhibitoren – Durchbruch bei der LDL-Cholesterin-Senkung? Dtsch. Med. Wochenschr. 141, 863-869 (2016)

Simons, K. ; Coskun, Ü. Membrane lipid galore. J. Mol. Biol. 428, 4737-4738 (2016)

Sosa, L. ; Torkko, J.M. ; Primo, M.E. ; Llovera, R.E. ; Toledo, P.L. ; Rios, A.S. ; Gonzalez Flecha, F.L. ; Trabucchi, A. ; Valdez, S.N. ; Poskus, E. ; Solimena, M. ; Ermácora, M.R. Biochemical, biophysical, and functional properties of ICA512/IA-2 RESP18 homology domain. Biochim. Biophys. Acta-Proteins Proteom. 1864, 511-522 (2016)

Struecker, B. ; Ludwig, S. ; Schmelzle, M. ; Ludwig, B. Cell transplantation for regeneration and function recovery before and after oncological resections. Onkologe 22, 478-487 (2016)

Ullrich, M. ; Bergmann, R. ; Peitzsch, M. ; Zenker, E.F. ; Cartellieri, M. ; Bachmann, M. ; Ehrhart-Bornstein, M. ; Block, N.L. ; Schally, A.V. ; Eisenhofer, G. ; Bornstein, S.R. ; Pietzsch, J. ; Ziegler, C.G. Multimodal somatostatin receptor theranostics using [64Cu]Cu-/[177Lu]Lu-DOTA-(Tyr3)octreotate and AN-238 in a mouse pheochromocytoma model. Theranostics 6, 650-665 (2016)

Ziegler, A.-G. ; Haupt, F. ; Scholz, M. ; Weininger, K. ; Wittich, S. ; Löbner, S. ; Matzke, C. ; Gezginci, C. ; Riethausen, S. ; Beyerlein, A. ; Zillmer, S. ; Amoroso, M. ; Coles, R. ; Powell, M. ; Furmaniak, J. ; Rees Smith, B. ; Winkler, C. ; Bonifacio, E. ; Achenbach, P. 3 screen ELISA for high-throughput detection of beta cell autoantibodies in capillary blood. Diabetes Technol. Ther. 18, 687-693 (2016)

2015

Balyura, M. ; Gelfgat, E. ; Ehrhart-Bornstein, M. ; Ludwig, B. ; Gendler, Z. ; Barkai, U. ; Zimerman, B. ; Rotem, A. ; Block, N.L. ; Schally, A.V. ; Bornstein, S.R. Transplantation of bovine adrenocortical cells encapsulated in alginate. Proc. Natl. Acad. Sci. U.S.A. 112, 2527-2532 (2015)

Benazra, M. ; Lecomte, M.J. ; Colace, C. ; Müller, A. ; Machado, C. ; Pechberty, S. ; Bricout-Neveu, E. ; Grenier-Godard, M. ; Solimena, M. ; Scharfmann, R. ; Czernichow, P. ; Ravassard, P. A human beta cell line with drug inducible excision of immortalizing transgenes. Mol. Metab. 4, 916-925 (2015)

Bergmann, A. ; Schwarz, P.E. Dem Diabetes davonlaufen, den Diabetes wegessen. Diabetes akt. 13, 3 (2015)

Bergmann, A. ; Schwarz, P.E. Herz im Visier. Diabetes akt. 13, 99 (2015)

Beutel, O. ; Roder, F. ; Birkholz, O. ; Rickert, C. ; Steinhoff, H. ; Grzybek, M. ; Coskun, Ü. ; Piehler, J. Two-dimensional trap for ultrasensitive quantification of transient protein interactions. ACS Nano 9, 9783-9791 (2015)

Bonifacio, E. ; Ziegler, A.-G. ; Klingensmith, G. ; Schober, E. ; Bingley, P.J. ; Rottenkolber, M. ; Theil, A. ; Eugster, A. ; Puff, R. ; Peplow, C. ; Buettner, F. ; Lange, K. ; Hasford, J. ; Achenbach, P. Effects of high-dose oral insulin on immune responses in children at high risk for type 1 diabetes: The Pre-POINT randomized clinical trial. JAMA 313, 1541-1549 (2015)

Bonifacio, E. Predicting type 1 diabetes using biomarkers. Diabetes Care 38, 989-996 (2015)

Bork, U. ; Rahbari, N.N. ; Schölch, S. ; Reissfelder, C. ; Kahlert, C. ; Büchler, M.W. ; Weitz, J. ; Koch, M. Circulating tumour cells and outcome in non-metastatic colorectal cancer: A prospective study. Br. J. Cancer 112, 1306-1313 (2015)

Brooke-Smith, M. ; Figueras, J. ; Ullah, S. ; Rees, M. ; Vauthey, J.N. ; Hugh, T.J. ; Garden, O.J. ; Fan, S.T. ; Crawford, M. ; Makuuchi, M. ; Yokoyama, Y. ; Büchler, M. ; Weitz, J. ; Padbury, R. Prospective evaluation of the International Study Group for Liver Surgery definition of bile leak after a liver resection and the role of routine operative drainage: an international multicentre study. HPB 17, 46-51 (2015)

Catar, R.A. ; Müller, G. ; Brandt, A. ; Langbein, H. ; Brunssen, C. ; Goettsch, C. ; Frenzel, A. ; Hofmann, A. ; Goettsch, W. ; Steinbronn, N. ; Strasser, R.H. ; Schubert, U. ; Ludwig, B. ; Bornstein, S.R. ; Morawietz, H. Increased gene expression of the cardiac endothelin system in obese mice. Horm. Metab. Res. 47, 509-515 (2015)

Chmelova, H. ; Cohrs, C.M. ; Chouinard, J.A. ; Petzold, C. ; Kuhn, M. ; Chen, C. ; Roeder, I. ; Kretschmer, K. ; Speier, S. Distinct roles of β-cell mass and function during type 1 diabetes onset and remission. Diabetes 64, 2148-2160 (2015)

Chmiel, R. ; Giannopoulou, E.Z. ; Winkler, C. ; Achenbach, P. ; Ziegler, A.-G. ; Bonifacio, E. Progression from single to multiple islet autoantibodies often occurs soon after seroconversion: Implications for early screening. Diabetologia 58, 411-413 (2015)

Choi, E.Y. ; Lim, J.H. ; Neuwirth, A. ; Economopoulou, M. ; Chatzigeorgiou, A. ; Chung, K.-J. ; Bittner, S. ; Lee, S.H. ; Langer, H. ; Samus, M. ; Kim, H. ; Cho, G.S. ; Ziemssen, T. ; Bdeir, K. ; Chavakis, E. ; Koh, J.Y. ; Boon, L. ; Hosur, K. ; Bornstein, S.R. ; Meuth, S.G. ; Hajishengallis, G. ; Chavakis, T. Developmental endothelial locus-1 is a homeostatic factor in the central nervous system limiting neuroinflammation and demyelination. Mol. Psychiatry 20, 880–888 (2015)

Czogalla, A. ; Kauert, D.J. ; Seidel, R. ; Schwille, P. ; Petrov, E.P. DNA origami nanoneedles on freestanding lipid membranes as a tool to observe isotropic-nematic transition in two dimensions. Nano Lett. 15, 649-655 (2015)

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Straatman, J. ; van der Wielen, N. ; Cuesta, M.A. ; Gisbertz, S.S. ; Hartemink, K.J. ; Alonso Poza, A. ; Weitz, J. ; Vallejo, F.M. ; Ahktar, K. ; Diez Del Val, I. ; Roig Garcia, J. ; van der Peet, D.L. Surgical techniques, open versus minimally invasive gastrectomy after chemotherapy (STOMACH trial): Study protocol for a randomized controlled trial. Trials 16:123 (2015)

Sue, M. ; Martucci, V. ; Frey, F. ; Lenders, J.M. ; Timmers, H.J. ; Peczkowska, M. ; Prejbisz, A. ; Swantje, B. ; Bornstein, S.R. ; Arlt, W. ; Fassnacht, M. ; Beuschlein, F. ; Robledo, M. ; Pacak, K. ; Eisenhofer, G. Lack of utility of SDHB mutation testing in adrenergic metastatic phaeochromocytoma. Eur. J. Endocrinol. 172, 89-95 (2015)

Swierczynska, M.M. ; Mateska, I. ; Peitzsch, M. ; Bornstein, S.R. ; Chavakis, T. ; Eisenhofer, G. ; Lamounier-Zepter, V. ; Eaton, S. Changes in morphology and function of adrenal cortex in mice fed a high-fat diet. Int. J. Obes. 39, 321-330 (2015)

Toporkiewicz, M. ; Meissner, J. ; Matusewicz, L. ; Czogalla, A. ; Sikorski, A.F. Toward a magic or imaginary bullet? Ligands for drug targeting to cancer cells: Principles, hopes, and challenges. Int. J. Nanomed. 10, 1399-1414 (2015)

Torkko, J.M. ; Primo, M.E. ; Dirk, R. ; Friedrich, A. ; Viehrig, A. ; Vergari, E. ; Borgonovo, B. ; Sönmez, A. ; Wegbrod, C. ; Lachnit, M. ; Münster, C. ; Sica, M.P. ; Ermácora, M.R. ; Solimena, M. Stability of proICA512/IA-2 and its targeting to insulin secretory granules require β4-sheet-mediated dimerization of its ectodomain in the endoplasmic reticulum. Mol. Cell. Biol. 35, 914-927 (2015)

Törn, C. ; Hadley, D. ; Lee, H.S. ; Hagopian, W. ; Lernmark, A. ; Simell, O. ; Rewers, M. ; Ziegler, A.-G. ; Schatz, D. ; Akolkar, B. ; Onengut-Gumuscu, S. ; Chen, W.M. ; Toppari, J. ; Mykkänen, J. ; Ilonen, J. ; Rich, S.S. ; She, J.X. ; Steck, A.K. ; Krischer, J. ; TEDDY Study Group (Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.) Role of Type 1 diabetes associated SNPs on risk of autoantibody positivity in the TEDDY study. Diabetes 64, 1818-1829 (2015)

van den Berg, S.M. ; Seijkens, T.T. ; Kusters, P.J. ; Zarzycka, B. ; Beckers, L. ; den Toom, M. ; Gijbels, M.J. ; Chatzigeorgiou, A. ; Weber, C. ; de Winther, M.P. ; Chavakis, T. ; Nicolaes, G.A.F. ; Lutgens, E. Blocking CD40-TRAF6 interactions by small-molecule inhibitor 6860766 ameliorates the complications of diet-induced obesity in mice. Int. J. Obes. 39, 782-790 (2015)

Vukicevic, V. ; Qin, N. ; Balyura, M. ; Eisenhofer, G. ; Wong, M.L. ; Licinio, J. ; Bornstein, S.R. ; Ehrhart-Bornstein, M. Valproic acid enhances neuronal differentiation of sympathoadrenal progenitor cells. Mol. Psychiatry 20, 941–950 (2015)

Warth, S.C. ; Höfig, K.P. ; Hiekel, A. ; Schallenberg, S. ; Jovanovic, K. ; Klein, L. ; Kretschmer, K. ; Ansel, K.M. ; Heissmeyer, V. Induced miR-99a expression represses Mtor cooperatively with miR-150 to promote regulatory T-cell differentiation. EMBO J. 34, 1195-1213 (2015)

Weber, G.F. ; Chousterman, B.G. ; He, S. ; Fenn, A.M. ; Nairz, M. ; Anzai, A. ; Brenner, T. ; Uhle, F. ; Iwamoto, Y. ; Robbins, C.S. ; Noiret, L. ; Maier, S.L. ; Zönnchen, T. ; Rahbari, N.N. ; Schölch, S. ; Klotzsche-von Ameln, A. ; Chavakis, T. ; Weitz, J. ; Hofer, S. ; Weigand, M.A. ; Nahrendorf, M. ; Weissleder, R. ; Swirski, F.K. Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis. Science 347, 1260-1265 (2015)

Weber, G.F. ; Maier, S.L. ; Zönnchen, T. ; Breucha, M. ; Seidlitz, T. ; Kutschick, I. ; Weitz, J. Analysis of circulating plasmacytoid dendritic cells during the course of sepsis. Surgery 158, 248-254 (2015)

Winkler, T.W. ; Justice, A.E. ; Graff, M. ; Barata, L. ; Feitosa, M.F. ; Chu, S. ; Czajkowski, J. ; Esko, T. ; Fall, T. ; Kilpeläinen, T.O. ; Lu, Y. ; Mägi, R. ; Mihailov, E. ; Pers, T.H. ; Rüeger, S. ; Teumer, A. ; Ehret, G.B. ; Ferreira, T. ; Heard-Costa, N.L. ; Karjalainen, J. ; Lagou, V. ; Mahajan, A. ; Neinast, M.D. ; Prokopenko, I. ; Simino, J. ; Teslovich, T.M. ; Jansen, R. ; Westra, H.J. ; White, C.C. ; Absher, D. ; Ahluwalia, T.S. ; Ahmad, S. ; Albrecht, E. ; Alves, A.C. ; Bragg-Gresham, J.L. ; de Craen, A.J. ; Bis, J.C. ; Bonnefond, A. ; Boucher, G. ; Cadby, G. ; Cheng, Y.C. ; Chiang, C.W. ; Delgado, G. ; Demirkan, A. ; Dueker, N. ; Eklund, N. ; Eiriksdottir, G. ; Eriksson, J. ; Feenstra, B. ; Fischer, K. ; Frau, F. ; Galesloot, T.E. ; Geller, F. ; Goel, A. ; Gorski, M. ; Grammer, T.B. ; Gustafsson, S. ; Haitjema, S. ; Hottenga, J.J. ; Huffman, J.E. ; Jackson, A.U. ; Jacobs, K.B. ; Johansson, A. ; Kaakinen, M. ; Kleber, M.E. ; Lahti, J. ; Mateo Leach, I. ; Lehne, B. ; Liu, Y. ; 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Lannfelt, L. ; Lanzani, C. ; Lotay, V. ; Launer, L.J. ; Leander, K. ; Lindstrom, J. ; Linneberg, A. ; Liu, Y.P. ; Lobbens, S. ; Luben, R. ; Lyssenko, V. ; Männisto, S. ; Magnusson, P.K. ; McArdle, W.L. ; Menni, C. ; Merger, S. ; Milani, L. ; Montgomery, G.W. ; Morris, A.P. ; Narisu, N. ; Nelis, M. ; Ong, K.K. ; Palotie, A. ; Perusse, L. ; Pichler, I. ; Pilia, M.G. ; Pouta, A. ; Rheinberger, M. ; Ribel-Madsen, R. ; Richards, M. ; Rice, K.M. ; Rice, T.K. ; Rivolta, C. ; Salomaa, V. ; Sanders, A.R. ; Sarzynski, M.A. ; Scholtens, S. ; Scott, R.A. ; Scott, W.R. ; Sebert, S. ; Sengupta, S. ; Sennblad, B. ; Seufferlein, T. ; Silveira, A. ; Slagboom, P.E. ; Smit, J.H. ; Sparsø, T.H. ; Stirrups, K. ; Stolk, R.P. ; Stringham, H.M. ; Swertz, M.A. ; Swift, A.J. ; Syvanen, A.C. ; Tan, S.T. ; Thorand, B. ; Tönjes, A. ; Tremblay, A. ; Tsafantakis, E. ; van der Most, P.J. ; Völker, U. ; Vohl, M.C. ; Vonk, J.M. ; Waldenberger, M. ; Walker, R.W. ; Wennauer, R. ; Widen, E. ; Willemsen, G. ; Wilsgaard, T. ; Wright, A.F. ; Zillikens, M.C. ; van Dijk, S.C. ; van Schoor, N.M. ; Asselbergs, F.W. ; de Bakker, P.I. ; Beckmann, J.S. ; Beilby, J. ; Bennett, D.A. ; Bergman, R.N. ; Bergmann, S. ; Böger, C.A. ; Boehm, B.O. ; Boerwinkle, E. ; Boomsma, D.I. ; Bornstein, S.R. ; Bottinger, E.P. ; Bouchard, C. ; Chambers, J.C. ; Chanock, S.J. ; Chasman, D.I. ; Cucca, F. ; Cusi, D. ; Dedoussis, G. ; Erdmann, J. ; Eriksson, J.G. ; Evans, D.A. ; de Faire, U. ; Farrall, M. ; Ferrucci, L. ; Ford, I. ; Franke, L. ; Franks, P.W. ; Froguel, P. ; Gansevoort, R.T. ; Gieger, C. ; Grönberg, H. ; Gudnason, V. ; Gyllensten, U. ; Hall, P. ; Hamsten, A. ; van der Harst, P. ; Hayward, C. ; Heliövaara, M. ; Hengstenberg, C. ; Hicks, A.A. ; Hingorani, A. ; Hofman, A. ; Hu, F. ; Huikuri, H.V. ; Hveem, K. ; James, A.L. ; Jordan, J.M. ; Jula, A. ; Kähönen, M. ; Kajantie, E. ; Kathiresan, S. ; Kiemeney, L.A. ; Kivimaki, M. ; Knekt, P.B. ; Koistinen, H.A. ; Kooner, J.S. ; Koskinen, S. ; Kuusisto, J. ; Maerz, W. ; Martin, N.G. ; Laakso, M. ; Lakka, T.A. ; Lehtimäki, T. ; Lettre, G. ; Levinson, D.F. ; Lind, L. ; Lokki, M.L. ; Mäntyselkä, P. ; Melbye, M. ; Metspalu, A. ; Mitchell, B.D. ; Moll, F.L. ; Murray, J.C. ; Musk, A.W. ; Nieminen, M.S. ; Njølstad, I. ; Ohlsson, C. ; Oldehinkel, A.J. ; Oostra, B.A. ; Palmer, L.J. ; Pankow, J.S. ; Pasterkamp, G. ; Pedersen, N.L. ; Pedersen, O. ; Penninx, B.W. ; Perola, M. ; Peters, A. ; Polasek, O. ; Pramstaller, P.P. ; Psaty, B.M. ; Qi, L. ; Quertermous, T. ; Raitakari, O.T. ; Rankinen, T. ; Rauramaa, R. ; Ridker, P.M. ; Rioux, J.D. ; Rivadeneira, F. ; Rotter, J.I. ; Rudan, I. ; den Ruijter, H.M. ; Saltevo, J. ; Sattar, N. ; Schunkert, H. ; Schwarz, P.E. ; Shuldiner, A.R. ; Sinisalo, J. ; Snieder, H. ; Sørensen, T.I. ; Spector, T.D. ; Staessen, J.A. ; Stefania, B. ; Thorsteinsdottir, U. ; Stumvoll, M. ; Tardif, J.C. ; Tremoli, E. ; Tuomilehto, J. ; Uitterlinden, A.G. ; Uusitupa, M. ; Verbeek, A.L. ; Vermeulen, S.H. ; Viikari, J.S. ; Vitart, V. ; Völzke, H. ; Vollenweider, P. ; Waeber, G. ; Walker, M. ; Wallaschofski, H. ; Wareham, N.J. ; Watkins, H. ; Zeggini, E. ; CHARGE Consortium (Gieger, C. ; Meisinger, C. ; Prokisch, H. ; Wichmann, H.-E.) ; DIAGRAM Consortium (Klopp, N. ; Meyer, J.) ; GLGC Consortium ; Global BPgen Consortium (Döring, A.) ; ICBP Consortium (Meitinger, T.) ; MAGIC Consortium ; Chakravarti, A. ; Clegg, D.J. ; Cupples, L.A. ; Gordon-Larsen, P. ; Jaquish, C.E. ; Rao, D.C. ; Abecasis, G.R. ; Assimes, T.L. ; Barroso, I. ; Berndt, S.I. ; Boehnke, M. ; Deloukas, P. ; Fox, C.S. ; Groop, L.C. ; Hunter, D.J. ; Ingelsson, E. ; Kaplan, R.C. ; McCarthy, M.I. ; Mohlke, K.L. ; O'Connell, J.R. ; Schlessinger, D. ; Strachan, D.P. ; Stefansson, K. ; van Duijn, C.M. ; Hirschhorn, J.N. ; Lindgren, C.M. ; Heid, I.M. ; North, K.E. ; Borecki, I.B. ; Kutalik, Z. ; Loos, R.J. The influence of age and sex on genetic associations with adult body size and shape: A large-scale genome-wide interaction study. PLoS Genet. 11:e1005378 (2015)

Xie, T.Y. ; Ngo, S.T. ; Veldhuis, J.D. ; Jeffery, P.L. ; Chopin, L.K. ; Tschöp, M. ; Waters, M.J. ; Tolle, V. ; Epelbaum, J. ; Chen, C.C. ; Steyn, F.J. Effect of deletion of ghrelin-o-acyltransferase on the pulsatile release of growth hormone in mice. J. Neuroendocrinol. 27, 872-886 (2015)

Yang, C. ; Rahbari, N.N. ; Mees, S.T. ; Schaab, F. ; Koch, M. ; Weitz, J. ; Reissfelder, C. Staged resection of bilobar colorectal liver metastases: Surgical strategies. Langenbecks Arch. Surg. 400, 633-640 (2015)

Zhao, M. ; Choudhary, P. ; Srinivasan, P. ; Tang, H. ; Heaton, N. ; Fung, M. ; Barthel, A. ; Bornstein, S.R. ; Amiel, S.A. ; Huang, G.C. Modification of human islet preparation: An effective approach to improve graft outcome after islet transplantation? Horm. Metab. Res. 47, 72-77 (2015)

2014

Abe, T. ; Shin, J.T. ; Hosur, K. ; Udey, M.C. ; Chavakis, T. ; Hajishengallis, G. Regulation of osteoclast homeostasis and inflammatory bone loss by MFG-E8. J. Immunol. 193, 1383-1391 (2014)

Ansurudeen, I. ; Kopf, P.G. ; Gauthier, K.M. ; Bornstein, S.R. ; Cowley, A.W. ; Campbell, W.B. Aldosterone secretagogues increase adrenal blood flow in male rats. Endocrinology 155, 127-132 (2014)

Baessler, A. ; Lamounier-Zepter, V. ; Fenk, S. ; Strack, C. ; Lahmann, C. ; Loew, T. ; Schmitz, G. ; Blüher, M. ; Bornstein, S.R. ; Fischer, M. Adipocyte fatty acid-binding protein levels are associated with left ventricular diastolic dysfunction in morbidly obese subjects. Nutr. Diabetes 4:e106 (2014)

Ban, R.H. ; Kamvissi, V. ; Schulte, K.M. ; Bornstein, S.R. ; Rubino, F. ; Graessler, J. Lipidomic profiling at the interface of metabolic surgery and cardiovascular disease. Curr. Atheroscler. Rep. 16:455 (2014)

Bellemann, N. ; Sommer, C.M. ; Mokry, T. ; Kortes, N. ; Gnutzmann, D. ; Gockner, T. ; Schmitz, A. ; Weitz, J. ; Kauczor, H.U. ; Radeleff, B. ; Stampfl, U. Hepatic artery stent-grafts for the emergency treatment of acute bleeding. Eur. J. Radiol. 83, 1799-1803 (2014)

Beyerlein, A. ; Chmiel, R. ; Hummel, S. ; Winkler, C. ; Bonifacio, E. ; Ziegler, A.-G. Timing of gluten introduction and islet autoimmunity in young children: Updated results from the BABYDIET study. Diabetes Care 37, e194-e195 (2014)

Birkenfeld, A.L. ; Shulman, G.I. Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 diabetes. Hepatology 59, 713-723 (2014)

Bogusławska, D.M. ; Machnicka, B. ; Hryniewicz-Jankowska, A. ; Czogalla, A. Spectrin and phospholipids - the current picture of their fascinating interplay. Cell. Mol. Biol. Lett. 19, 158-179 (2014)

Bonifacio, E. ; Krumsiek, J. ; Winkler, C. ; Theis, F.J. ; Ziegler, A.-G. A strategy to find gene combinations that identify children who progress rapidly to type 1 diabetes after islet autoantibody seroconversion. Acta Diabetol. 51, 403-411 (2014)

Borg, D.J. ; Weigelt, M. ; Wilhelm, C. ; Gerlach, M. ; Bickle, M. ; Speier, S. ; Bonifacio, E. ; Hommel, A. Mesenchymal stromal cells improve transplanted islet survival and islet function in a syngeneic mouse model. Diabetologia 57, 522-531 (2014)

Bork, U. ; Grützmann, R. ; Rahbari, N.N. ; Schölch, S. ; Distler, M. ; Reissfelder, C. ; Koch, M. ; Weitz, J. Prognostic relevance of minimal residual disease in colorectal cancer. World J. Gastroenterol. 20, 10296-10304 (2014)

Bornstein, S.R. ; Amiel, S.A. ; Rubino, F. ; Mingrone, G. ; Kamvissi, V. ; Solimena, M. ; Bonifacio, E. ; Jones, P. ; Schwarz, P. ; Birkenfeld, A.L. ; Behrens, A. ; Barthel, A. ; Lechler, R. ; Peakman, M. Creating a "Transcampus" in diabetes research between King's College London and the Technische Universität Dresden: Update on islet biology and transplantation. Horm. Metab. Res. 47, DOI: 10.1055/s-0034-1396842 (2014)

Chatzigeorgiou, A. ; Chung, K.-J. ; Garcia-Martin, R. ; Alexaki, V.I. ; Klotzsche-von Ameln, A. ; Phieler, J. ; Sprott, D. ; Kanczkowski, W. ; Tzanavari, T. ; Bdeir, M. ; Bergmann, S. ; Cartellieri, M. ; Bachmann, M. ; Nikolakopoulou, P. ; Androutsellis-Theotokis, A. ; Siegert, G. ; Bornstein, S.R. ; Muders, M.H. ; Boon, L. ; Karalis, K.P. ; Lutgens, E. ; Chavakis, T. Dual role of B7 costimulation in obesity-related nonalcoholic steatohepatitis and metabolic dysregulation. Hepatology 60, 1196-1210 (2014)

Chatzigeorgiou, A. ; Seijkens, T. ; Zarzycka, B. ; Engel, D. ; Poggi, M. ; van den Berg, S. ; Soehnlein, O. ; Winkels, H. ; Beckers, L. ; Lievens, D. ; Driessen, A. ; Kusters, P. ; Biessen, E. ; Garcia-Martin, R. ; Klotzsche-von Ameln, A. ; Gijbels, M.J. ; Noelle, R. ; Boon, L. ; Hackeng, T.M. ; Schulte, K.M. ; Schulte, K. ; Xu, A. ; Vriend, G. ; Nabuurs, S.B. ; Chung, K.-J. ; Willems van Dijk, K. ; Rensen, P.C. ; Gerdes, N. ; de Winther, M.P. ; Block, N.L. ; Schally, A.V. ; Weber, C. ; Bornstein, S.R. ; Nicolaes, G.A.F. ; Chavakis, T. ; Lutgens, E. Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance. Proc. Natl. Acad. Sci. U.S.A. 111, 2686-2691 (2014)

Choi, T.Y. ; Ninov, N. ; Stainier, D.Y. ; Shin, D. Extensive conversion of hepatic biliary epithelial cells to hepatocytes after near total loss of hepatocytes in zebrafish. Gastroenterology 146, 776-788 (2014)

Chung, K.-J. ; Mitroulis, I. ; Wiessner, J.R. ; Zheng, Y.Y. ; Siegert, G. ; Sperandio, M. ; Chavakis, T. A novel pathway of rapid TLR-triggered activation of integrin-dependent leukocyte adhesion that requires Rap1 GTPase. Mol. Biol. Cell 25, 2948-2955 (2014)

Czogalla, A. ; Grzybek, M. ; Jones, W. ; Coskun, Ü. Validity and applicability of membrane model systems for studying interactions of peripheral membrane proteins with lipids. Biochim. Biophys. Acta-Mol. Cell Biol. Lipids 1841, 1049-1059 (2014)

Därr, R. ; Pamporaki, C. ; Peitzsch, M. ; Miehle, K. ; Prejbisz, A. ; Peczkowska, M. ; Weismann, D. ; Beuschlein, F. ; Sinnott, R. ; Bornstein, S.R. ; Neumann, H.P. ; Januszewicz, A. ; Lenders, J.W. ; Eisenhofer, G. Biochemical diagnosis of phaeochromocytoma using plasma-free normetanephrine, metanephrine and methoxytyramine: Importance of supine sampling under fasting conditions. Clin. Endocrinol. 80, 478-486 (2014)

Distler, M. ; Kersting, S. ; Rückert, F. ; Kross, P. ; Saeger, H.-D. ; Weitz, J. ; Grützmann, R. Chronic pancreatitis of the pancreatic remnant is an independent risk factor for pancreatic fistula after distal pancreatectomy. BMC Surg. 14:54 (2014)

Distler, M. ; Aust, D. ; Weitz, J. ; Pilarsky, C. ; Grützmann, R. Precursor lesions for sporadic pancreatic cancer: PanIN, IPMN, and MCN. Biomed Res. Int. 2014:474905 (2014)

Economopoulou, M. ; Masjkur, J. ; Raiskup, F. ; Ebermann, D. ; Saha, S. ; Karl, M.O. ; Funk, R. ; Jaszai, J. ; Chavakis, T. ; Ehrhart-Bornstein, M. ; Pillunat, L.E. ; Kunz-Schughart, L.A. ; Kurth, I. ; Dubrovska, A. ; Androutsellis-Theotokis, A. Expression of the transcription factor Hes3 in the mouse and human ocular surface, and in pterygium. Int. J. Radiat. Biol. 90, 700-709 (2014)

Elding Larsson, H. ; Vehik, K. ; Gesualdo, P. ; Akolkar, B. ; Hagopian, W. ; Krischer, J.P. ; Lernmark, A. ; Rewers, M. ; Simell, O. ; She, J.-X. ; Ziegler, A.-G. ; Haller, M.J. ; TEDDY Study Group (Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.) Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease. Pediatr. Diabetes 15, 118-126 (2014)

Endesfelder, D. ; zu Castell, W. ; Ardissone, A. ; Davis-Richardson, A.G. ; Achenbach, P. ; Hagen, M. ; Pflueger, M. ; Gano, K.A. ; Fagen, J.R. ; Drew, J.C. ; Brown, C.T. ; Kolaczkowski, B. ; Atkinson, M.J. ; Schatz, D. ; Bonifacio, E. ; Triplett, E.W. ; Ziegler, A.-G. Compromised gut microbiota networks in children with anti-islet cell autoimmunity. Diabetes 63, 2006-2014 (2014)

Ferreira, R.C. ; Guo, H. ; Coulson, R.M. ; Smyth, D.J. ; Pekalski, M.L. ; Burren, O.S. ; Cutler, A.J. ; Doecke, J.D. ; Flint, S. ; McKinney, E.F. ; Lyons, P.A. ; Smith, K.G. ; Achenbach, P. ; Beyerlein, A. ; Dunger, D.B. ; Wicker, L.S. ; Todd, J.A. ; Bonifacio, E. ; Wallace, C. ; Ziegler, A.-G. A type I interferon transcriptional signature precedes autoimmunity in children genetically at risk of type 1 diabetes. Diabetes 63, 2538-2550 (2014)

Folprecht, G. ; Gruenberger, T. ; Bechstein, W. ; Raab, H.R. ; Weitz, J. ; Lordick, F. ; Hartmann, J.T. ; Stoehlmacher-Williams, J. ; Lang, H. ; Trarbach, T. ; Liersch, T. ; Ockert, D. ; Jaeger, D. ; Steger, U. ; Suedhoff, T. ; Rentsch, A. ; Köhne, C.H. Survival of patients with initially unresectable colorectal liver metastases treated with FOLFOX/cetuximab or FOLFIRI/cetuximab in a multidisciplinary concept (CELIM study). Ann. Oncol. 25, 1018-1025 (2014)

Folprecht, G. ; Weitz, J. ; Hoffmann, R.T. CT-morphologische Evaluation neoadjuvanter Chemotherapie. Chirurg 85, 31-36 (2014)

Franquelim, H.G. ; Linko, V. ; Czogalla, A. ; Dietz, H. ; Schwille, P. Synthetic membrane curvature-inducing DNA origami scaffolds. Biophys. J. 106:617a (2014)

Fuchs, Y.F. ; Adler, K. ; Lindner, A. ; Karasinsky, A. ; Wilhelm, C. ; Weigelt, M. ; Balke, H. ; Förtsch, K. ; Mortler-Hildebrandt, L.F. ; Harlan, D.M. ; Pechhold, K. ; Ziegler, A.-G. ; Bonifacio, E. Igrp and insulin vaccination induce CD8+ T cell mediated autoimmune diabetes in the RIP-CD80GP mouse. Clin. Exp. Immunol. 176, 199-206 (2014)

Gattu, A.K. ; Birkenfeld, A.L. ; Iwakiri, Y. ; Jay, S. ; Saltzman, M. ; Doll, J. ; Protiva, P. ; Samuel, V.T. ; Crawford, S.E. ; Chung, C. Pigment epithelium-derived factor (PEDF) suppresses IL-1β-mediated c-Jun N-terminal kinase (JNK) activation to improve hepatocyte insulin signaling. Endocrinology 155, 1373-1385 (2014)

Gerl, M.J. ; Sachsenheimer, T. ; Grzybek, M. ; Coskun, Ü. ; Wieland, F.T. ; Brügger, B. Analysis of transmembrane domains and lipid modified peptides with matrix-assisted laser desorption ionization-time-of-flight mass spectrometry. Anal. Chem. 86, 3722-3726 (2014)

Graessler, J. ; Bornstein, T.D. ; Goel, D. ; Bhalla, V.P. ; Lohmann, T. ; Wolf, T. ; Koch, M. ; Qin, Y. ; Licinio, J. ; Wong, M.L. ; Chavakis, T. ; Xu, A. ; Shevchenko, A. ; Schuhmann, K. ; Schwarz, P.E. ; Schulte, K.M. ; Patel, A. ; Bornstein, S.R. Lipidomic profiling before and after Roux-en-Y gastric bypass in obese patients with diabetes. Pharmacogenomics J. 14, 201-207 (2014)

Grützmann, R. ; Kersting, S. ; Distler, M. ; Weitz, J. Arterielle Rekonstruktion beim duktalen Pankreaskarzinom – Darstellung chirurgischer Techniken. Zentralbl. Chir. 139, 261-264 (2014)

Hackert, T. ; Weitz, J. ; Büchler, M.W. Splenic artery use for arterial reconstruction in pancreatic surgery. Langenbecks Arch. Surg. 399, 667-671 (2014)

Hajishengallis, G. ; Chavakis, T. ; Hajishengallis, E. ; Lambris, J.D. Neutrophil homeostasis and inflammation: Novel paradigms from studying periodontitis. J. Leukoc. Biol., DOI: 10.1189/jlb.3VMR1014-468R (2014)

Hanefeld, M. ; Bornstein, S.R. ; Barthel, A. Moderne medikamentöse Therapie des Typ-2-Diabetes. Dtsch. Med. Wochenschr. 139, 2494-2497 (2014)

Hummel, S. ; Vehik, K. ; Uusitalo, U. ; McLeod, W. ; Aronsson, C.A. ; Frank, N. ; Gesualdo, P. ; Yang, J. ; Norris, J.M. ; Virtanen, S.M. ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.) Infant feeding patterns in families with a diabetes history - observations from The Environmental Determinants of Diabetes in the Young (TEDDY) birth cohort study. Public Health Nutr. 17, 2853-2862 (2014)

Kahlert, C. ; Fiala, M. ; Musso, G. ; Halama, N. ; Keim, S. ; Mazzone, M. ; Lasitschka, F. ; Pecqueux, M. ; Klupp, F. ; Schmidt, T. ; Rahbari, N.N. ; Schölch, S. ; Pilarsky, C. ; Ulrich, A. ; Schneider, M. ; Weitz, J. ; Koch, M. Prognostic impact of a compartment-specific angiogenic marker profile in patients with pancreatic cancer. Oncotarget 5, 12978-12989 (2014)

Kahlert, C. ; Melo, S.A. ; Protopopov, A. ; Tang, J. ; Seth, S. ; Koch, M. ; Zhang, J. ; Weitz, J. ; Chin, L. ; Futreal, A. ; Kalluri, R. Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer. J. Biol. Chem. 289, 3869-3875 (2014)

Kibbey, R.G. ; Choi, C.S. ; Lee, H.Y. ; Cabrera, O. ; Pongratz, R.L. ; Zhao, X. ; Birkenfeld, A.L. ; Li, C. ; Berggren, P.O. ; Stanley, C. ; Shulman, G.I. Mitochondrial GTP insensitivity contributes to hypoglycemia in hyperinsulinemia hyperammonemia by inhibiting glucagon release. Diabetes 63, 4218-4229 (2014)

Kirchberg, J. ; Weitz, J. Minimalinvasive Chirurgie primärer und sekundärer Lebertumoren. Chirurg 85, 689-695 (2014)

Knoch, K.P. ; Nath-Sain, S. ; Petzold, A. ; Schneider, H. ; Beck, M. ; Wegbrod, C. ; Sönmez, A. ; Münster, C. ; Friedrich, A. ; Roivainen, M. ; Solimena, M. PTBP1 is required for glucose-stimulated cap-independent translation of insulin granule proteins and Coxsackieviruses in beta cells. Mol. Metab. 3, 518-530 (2014)

Krause, S. ; Landherr, U. ; Agardh, C.-D. ; Hausmann, S. ; Link, K. ; Hansen, J.M. ; Lynch, K.F. ; Powell, M. ; Furmaniak, J. ; Rees-Smith, B. ; Bonifacio, E. ; Ziegler, A.-G. ; Lernmark, A. ; Achenbach, P. GAD autoantibody affinity in adult patients with latent autoimmune diabetes, the study participants of a GAD65 vaccination trial. Diabetes Care 37, 1675-1680 (2014)

Krause, S. ; Beyerlein, A. ; Winkler, C. ; Gavrisan, A. ; Kayser, C. ; Puff, R. ; Bonifacio, E. ; Ziegler, A.-G. ; Achenbach, P. Soluble interleukin-2 receptor alpha in preclinical type 1 diabetes. Acta Diabetol. 51, 517-518 (2014)

Krautz, C. ; Kuithan, F. ; Dobroschke, J. ; Nagel, I. ; Hartmann, S. ; Aust, D.E. ; Baretton, G. ; Weitz, J. ; Reissfelder, C. Peritoneal dissemination of a gastric API2-MALT1-positive MALT lymphoma. J. Clin. Pathol. 67, 746-748 (2014)

Lee, H.S. ; Burkhardt, B.R. ; McLeod, W. ; Smith, S. ; Eberhard, C. ; Lynch, K. ; Hadley, D. ; Rewers, M. ; Simell, O. ; She, J.X. ; Hagopian, B. ; Lernmark, A. ; Akolkar, B. ; Ziegler, A.-G. ; Krischer, J.P. ; TEDDY Study Group (Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.) Biomarker discovery study design for type 1 diabetes in The Environmental Determinants of Diabetes in the Young (TEDDY) study. Diabetes Metab. Res. Rev. 30, 424-434 (2014)

Lee, H.Y. ; Gattu, A.K. ; Camporez, J.P. ; Kanda, S. ; Guigni, B. ; Kahn, M. ; Zhang, D. ; Galbo, T. ; Birkenfeld, A.L. ; Jornayvaz, F.R. ; Jurczak, M.J. ; Choi, C.S. ; Yan, Z. ; Williams, R.S. ; Shulman, G.I. ; Samuel, V.T. Muscle-specific activation of Ca(2+)/calmodulin-dependent protein kinase IV increases whole-body insulin action in mice. Diabetologia 57, 1232-1241 (2014)

Liang, Q. ; Zhong, L. ; Zhang, J. ; Wang, Y. ; Bornstein, S.R. ; Triggle, C.R. ; Ding, H. ; Lam, K.S. ; Xu, A. FGF21 maintains glucose homeostasis by mediating the cross talk between liver and brain during prolonged fasting. Diabetes 63, 4064-4075 (2014)

Liu, E. ; Lee, H.S. ; Aronsson, C.A. ; Hagopian, W.A. ; Koletzko, S. ; Rewers, M.J. ; Eisenbarth, G.S. ; Bingley, P.J. ; Bonifacio, E. ; Simell, V. ; Agardh, D. ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.) Risk of pediatric celiac disease according to HLA haplotype and country. N. Engl. J. Med. 371, 42-49 (2014)

Ludwig, B. ; Barthel, A. ; Reichel, A. ; Block, N.L. ; Ludwig, S. ; Schally, A.V. ; Bornstein, S.R. Modulation of the pancreatic islet-stress axis as a novel potential therapeutic target in diabetes mellitus. Vitam. Horm. 95, 195-222 (2014)

Machnicka, B. ; Czogalla, A. ; Hryniewicz-Jankowska, A. ; Bogusławska, D.M. ; Grochowalska, R. ; Heger, E. ; Sikorski, A.F. Spectrins: A structural platform for stabilization and activation of membrane channels, receptors and transporters. Biochim. Biophys. Acta-Biomembr. 1838, 620-634 (2014)

Masjkur, J. ; Arps-Forker, C. ; Poser, S.W. ; Nikolakopoulou, P. ; Toutouna, L. ; Chenna, R. ; Chavakis, T. ; Chatzigeorgiou, A. ; Chen, L.S. ; Dubrovska, A. ; Choudhary, P. ; Uphues, I. ; Mark, M. ; Bornstein, S.R. ; Androutsellis-Theotokis, A. Hes3 is expressed in the adult pancreatic islet and regulates gene expression, cell growth, and insulin release. J. Biol. Chem. 289, 35503-35516 (2014)

Masjkur, J. ; Levenfus, I. ; Lange, S. ; Arps-Forker, C. ; Poser, S.W. ; Qin, N. ; Vukicevic, V. ; Chavakis, T. ; Eisenhofer, G. ; Bornstein, S.R. ; Ehrhart-Bornstein, M. ; Androutsellis-Theotokis, A. A defined, controlled culture system for primary bovine chromaffin progenitors reveals novel biomarkers and modulators. Stem Cells Trans. Med. 3, 801-808 (2014)

Mayer, C.T. ; Lahl, K. ; Milanez-Almeida, P. ; Watts, D. ; Dittmer, U. ; Fyhrquist, N. ; Huehn, J. ; Kopf, M. ; Kretschmer, K. ; Rouse, B. ; Sparwasser, T. Advantages of Foxp3+ regulatory T cell depletion using DEREG mice. Immun. Inflamm. Dis. 2, 162-165 (2014)

Mitroulis, I. ; Kang, Y.Y. ; Gahmberg, C.G. ; Siegert, G. ; Hajishengallis, G. ; Chavakis, T. ; Choi, E.Y. Developmental endothelial locus-1 attenuates complement-dependent phagocytosis through inhibition of Mac-1-integrin. Thromb. Haemost. 111, 1004-1006 (2014)

Moutsopoulos, N.M. ; Konkel, J. ; Sarmadi, M. ; Eskan, M.A. ; Wild, T. ; Dutzan, N. ; Abusleme, L. ; Zenobia, C. ; Hosur, K.B. ; Abe, T. ; Uzel, G. ; Chen, W. ; Chavakis, T. ; Holland, S.M. ; Hajishengallis, G. Defective neutrophil recruitment in leukocyte adhesion deficiency type I disease causes local IL-17-driven inflammatory bone loss. Sci. Transl. Med. 6:229ra40 (2014)

Neuschäfer-Rube, F. ; Lieske, S. ; Kuna, M. ; Henkel, J. ; Perry, R.J. ; Erion, D.M. ; Pesta, D. ; Willmes, D.M. ; Brachs, S. ; von Loeffelholz, C. ; Tolkachov, A. ; Schupp, M. ; Pathe-Neuschäfer-Rube, A. ; Pfeiffer, A.F. ; Shulman, G.I. ; Püschel, G.P. ; Birkenfeld, A.L. The mammalian INDY homolog is induced by CREB in a rat model of type 2 diabetes. Diabetes 63, 1048-1057 (2014)

Niebling, J. ; Rünker, A. ; Schallenberg, S. ; Kretschmer, K. ; Kempermann, G. Myelin-specific T helper 17 cells promote adult hippocampal neurogenesis through indirect mechanisms. F1000Res. 3:169 (2014)

Pamporaki, C. ; Bursztyn, M. ; Reimann, M. ; Ziemssen, T. ; Bornstein, S.R. ; Sweep, F.C. ; Timmers, H. ; Lenders, J.W. ; Eisenhofer, G. Seasonal variation in plasma free normetanephrine concentrations: Implications for biochemical diagnosis of pheochromocytoma. Eur. J. Endocrinol. 170, 349-357 (2014)

Parfentyeva, E. ; Saha, S. ; Hjellset, V.T. ; Kopprasch, S. ; Schwarz, P.E. Assessment of small C-fiber status for screening of oxidative stress in patients at risk of diabetes. Horm. Metab. Res. 46, 360-364 (2014)

Petrov, E.P. ; Czogalla, A. ; Kauert, D.J. ; Seidel, R. ; Schwille, P. Diffusion and freezing transition of rod-like DNA origami on freestanding lipid membranes. Biophys. J. 106:701a (2014)

Petzold, C. ; Steinbronn, N. ; Gereke, M. ; Strasser, R.H. ; Sparwasser, T. ; Bruder, D. ; Geffers, R. ; Schallenberg, S. ; Kretschmer, K. Fluorochrome-based definition of naturally occurring Foxp3+ regulatory T cells of intra- and extrathymic origin. Eur. J. Immunol. 44, 3632-3645 (2014)

Qin, N. ; de Cubas, A.A. ; Garcia-Martin, R. ; Richter, S. ; Peitzsch, M. ; Menschikowski, M. ; Lenders, J.W. ; Timmers, H.J. ; Mannelli, M. ; Opocher, G. ; Economopoulou, M. ; Siegert, G. ; Chavakis, T. ; Pacak, K. ; Robledo, M. ; Eisenhofer, G. Opposing effects of HIF1α and HIF2α on chromaffin cell phenotypic features and tumor cell proliferation: Insights from MYC-associated factor X. Int. J. Cancer 135, 2054-2064 (2014)

Rahbari, N.N. ; Reissfelder, C. ; Schulze-Bergkamen, H. ; Jäger, D. ; Büchler, M.W. ; Weitz, J. ; Koch, M. Adjuvant therapy after resection of colorectal liver metastases: the predictive value of the MSKCC clinical risk score in the era of modern chemotherapy. BMC Cancer 14:174 (2014)

Rahbari, N.N. ; Elbers, H. ; Koch, M. ; Vogler, P. ; Striebel, F. ; Bruckner, T. ; Mehrabi, A. ; Schemmer, P. ; Büchler, M.W. ; Weitz, J. Randomized clinical trial of stapler versus clamp-crushing transection in elective liver resection. Br. J. Surg. 101, 200-207 (2014)

Reissfelder, C. ; Brand, K. ; Sobiegalla, J. ; Rahbari, N.N. ; Bork, U. ; Schirmacher, P. ; Büchler, M.W. ; Weitz, J. ; Koch, M. Chemotherapy-associated liver injury and its influence on outcome after resection of colorectal liver metastases. Surgery 155, 245-254 (2014)

Reißfelder, C. ; Kirchberg, J. ; Weitz, J. Nervenschonende offene tiefe anteriore Rektumresektion beim Rektumkarzinom. Zentralbl. Chir. 139, 381-383 (2014)

Roth, R. ; Lynch, K. ; Lernmark, B. ; Baxter, J. ; Simell, T. ; Smith, L. ; Swartling, U. ; Ziegler, A.-G. ; Johnson, S.B. ; TEDDY Study Group (Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.) Maternal anxiety about a child's diabetes risk in the TEDDY study: The potential role of life stress, postpartum depression, and risk perception. Pediatr. Diabetes 16, 287-298 (2014)

Schlottmann, I. ; Ehrhart-Bornstein, M. ; Wabitsch, M. ; Bornstein, S.R. ; Lamounier-Zepter, V. Calcium-dependent release of adipocyte fatty acid binding protein from human adipocytes. Int. J. Obes. 38, 1221-1227 (2014)

Schlueter, N. ; de Sterke, A. ; Willmes, D.M. ; Spranger, J. ; Jordan, J. ; Birkenfeld, A.L. Metabolic actions of natriuretic peptides and therapeutic potential in the metabolic syndrome. Pharmacol. Ther. 144, 12-27 (2014)

Schulte, K.M. ; Talat, N. ; Galata, G. ; Aylwin, S. ; Izatt, L. ; Eisenhofer, G. ; Barthel, A. ; Bornstein, S.R. Genetics and the clinical approach to paragangliomas. Horm. Metab. Res. 46, 964-973 (2014)

Schulte, K.M. ; Talat, N. ; Galata, G. ; Gilbert, J. ; Miell, J. ; Hofbauer, L.C. ; Barthel, A. ; Diaz-Cano, S. ; Bornstein, S.R. Oncologic resection achieving r0 margins improves disease-free survival in parathyroid cancer. Ann. Surg. Oncol. 21, 1891-1897 (2014)

Seijkens, T. ; Kusters, P. ; Chatzigeorgiou, A. ; Chavakis, T. ; Lutgens, E. Immune cell crosstalk in obesity: A key role for costimulation? Diabetes 63, 3982-3991 (2014)

Steinert, G. ; Schölch, S. ; Niemietz, T. ; Iwata, N. ; García, S.A. ; Behrens, B. ; Voigt, A. ; Kloor, M. ; Benner, A. ; Bork, U. ; Rahbari, N.N. ; Büchler, M.W. ; Stoecklein, N.H. ; Weitz, J. ; Koch, M. Immune escape and survival mechanisms in circulating tumor cells of colorectal cancer. Cancer Res. 74, 1694-1704 (2014)

Stumpp, C. ; Beyerlein, A. ; Ziegler, A.-G. ; Bonifacio, E. Neonatal and infant beta cell hormone concentrations in relation to type 1 diabetes risk. Pediatr. Diabetes 15, 528-533 (2014)

Tsourdi, E. ; Heidrich, F.M. ; Winzer, M. ; Röllig, C. ; Kirsch, C.M. ; Meinel, J. ; Baretton, G.B. ; Bornstein, S.R. ; Hofbauer, L.C. An exotic cause of exudative enteropathy. Am. J. Case Rep. 15, 226-229 (2014)

Tsuji, N. ; Ninov, N. ; Delawary, M. ; Osman, S. ; Roh, A.S. ; Gut, P. ; Stainier, D.Y. Whole organism high content screening identifies stimulators of pancreatic beta-cell proliferation. PLoS ONE 9:e104112 (2014)

Ullrich, M. ; Bergmann, R. ; Peitzsch, M. ; Cartellieri, M. ; Qin, N. ; Ehrhart-Bornstein, M. ; Block, N.L. ; Schally, A.V. ; Pietzsch, J. ; Eisenhofer, G. ; Bornstein, S.R. ; Ziegler, C.G. In vivo fluorescence imaging and urinary monoamines as surrogate biomarkers of disease progression in a mouse model of pheochromocytoma. Endocrinology 155, 4149-4156 (2014)

Vahl, J.C. ; Drees, C. ; Heger, K. ; Heink, S. ; Fischer, J.C. ; Nedjic, J. ; Ohkura, N. ; Morikawa, H. ; Poeck, H. ; Schallenberg, S. ; Rieß, D. ; Hein, M.Y. ; Buch, T. ; Polic, B. ; Schönle, A. ; Zeiser, R. ; Schmitt-Gräff, A. ; Kretschmer, K. ; Klein, L. ; Korn, T. ; Sakaguchi, S. ; Schmidt-Supprian, M. Continuous T cell receptor signals maintain a functional regulatory T cell pool. Immunity 41, 722-736 (2014)

van Noort, V. ; Schölch, S. ; Iskar, M. ; Zeller, G. ; Ostertag, K. ; Schweitzer, C. ; Werner, K. ; Weitz, J. ; Koch, M. ; Bork, P. Novel drug candidates for the treatment of metastatic colorectal cancer through global inverse gene-expression profiling. Cancer Res. 74, 5690-5699 (2014)

Volk, A. ; Rahbari, N.N. ; Koch, M. ; Weitz, J. Leistenhernienversorgung nach Lichtenstein. Zentralbl. Chir. 139, 581-582 (2014)

Walter, U. ; Kohlert, T. ; Rahbari, N.N. ; Weitz, J. ; Welsch, T. Impact of preoperative diabetes on long-term survival after curative resection of pancreatic adenocarcinoma: A systematic review and meta-analysis. Ann. Surg. Oncol. 21, 1082-1089 (2014)

Wang, Y. ; Xiao, Y. ; Zhong, L. ; Ye, D. ; Zhang, J. ; Tu, Y. ; Bornstein, S.R. ; Zhou, Z. ; Lam, K.S. ; Xu, A. Increased neutrophil elastase and proteinase 3 and augmented NETosis are closely associated with β-cell autoimmunity in patients with type 1 diabetes. Diabetes 63, 4239-4248 (2014)

Wieduwild, R. ; Lin, W. ; Boden, A. ; Kretschmer, K. ; Zhang, Y. A repertoire of peptide tags for controlled drug release from injectable noncovalent hydrogel. Biomacromolecules 15, 2058-2066 (2014)

Winkler, C. ; Krumsiek, J. ; Buettner, F. ; Angermüller, C. ; Giannopoulou, E.Z. ; Theis, F.J. ; Ziegler, A.-G. ; Bonifacio, E. Feature ranking of type 1 diabetes susceptibility genes improves prediction of type 1 diabetes. Diabetologia 57, 2521-2529 (2014)

Xiao, S. ; Yosef, N. ; Yang, J. ; Wang, Y. ; Zhou, L. ; Zhu, C. ; Wu, C. ; Baloglu, E. ; Schmidt, D. ; Ramesh, R. ; Lobera, M. ; Sundrud, M.S. ; Tsai, P.Y. ; Xiang, Z. ; Wang, J. ; Xu, Y. ; Lin, X. ; Kretschmer, K. ; Rahl, P.B. ; Young, R.A. ; Zhong, Z. ; Hafler, D.A. ; Regev, A. ; Ghosh, S. ; Marson, A. ; Kuchroo, V.K. Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms. Immunity 40, 477-489 (2014)

Yang, J. ; Lernmark, A. ; Uusitalo, U.M. ; Lynch, K.F. ; Veijola, R. ; Winkler, C. ; Larsson, H.E. ; Rewers, M. ; She, J.X. ; Ziegler, A.-G. ; Simell, O.G. ; Hagopian, W.A. ; Akolkar, B. ; Krischer, J.P. ; Vehik, K. ; TEDDY Study Group (Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K.) Prevalence of obesity was related to HLA-DQ in 2-4 year old children at genetic risk for type 1 diabetes. Int. J. Obes. 38, 1491-1496 (2014)

2013

Barkai, U. ; Weir, G.C. ; Colton, C.K. ; Ludwig, B. ; Bornstein, S.R. ; Brendel, M.D. ; Neufeld, T.P. ; Bremer, C. ; Leon, A. ; Evron, Y. ; Yavriyants, K. ; Azarov, D. ; Zimermann, B. ; Maimon, S. ; Shabtay, N. ; Balyura, M. ; Rozenshtein, T. ; Vardi, P. ; Bloch, K. ; de Vos, P. ; Rotem, A. Enhanced oxygen supply improves islet viability in a new bioartificial pancreas. Cell Transplant. 22, 1463-1476 (2013)

Bauer, K. ; Nelius, N. ; Reuschenbach, M. ; Koch, M. ; Weitz, J. ; Steinert, G. ; Kopitz, J. ; Beckhove, P. ; Tariverdian, M. ; von Knebel Doeberitz, M. ; Kloor, M. T cell responses against microsatellite instability-induced frameshift peptides and influence of regulatory T cells in colorectal cancer. Cancer Immunol. Immunother. 62, 27-37 (2013)

Bonifacio, E. Targeting innate immunity in type 1 diabetes: Strike one. Lancet 381, 1880-1881 (2013)

Calvet, J.H. ; Dupin, J. ; Winiecki, H. ; Schwarz, P.E. Assessment of small fiber neuropathy through a quick, simple and non-invasive method in a German diabetes outpatient clinic. Exp. Clin. Endocrinol. Diabet. 121, 80-83 (2013)

Chatzigeorgiou, A. ; Phieler, J. ; Gebler, J. ; Bornstein, S.R. ; Chavakis, T. CD40L stimulates the crosstalk between adipocytes and inflammatory cells. Horm. Metab. Res. 45, 741-747 (2013)

Chavakis, T. ; Ehrhart-Bornstein, M. The adrenal gland in the center. Horm. Metab. Res. 45, 79-80 (2013)

Chmelar, J. ; Chung, K.-J. ; Chavakis, T. The role of innate immune cells in obese adipose tissue inflammation and development of insulin resistance. Thromb. Haemost. 109, 399-406 (2013)

Czogalla, A. ; Petrov, E.P. ; Kauert, D.J. ; Uzunova, V. ; Zhang, Y. ; Seidel, R. ; Schwille, P. Switchable domain partitioning and diffusion of DNA origami rods on membranes. Faraday Discuss. 161, 31-43 (2013)

Dekkers, T. ; Deinum, J. ; Schultzekool, L.J. ; Blondin, D. ; Vonend, O. ; Hermus, A.R. ; Peitzsch, M. ; Rump, L.C. ; Antoch, G. ; Sweep, F.C. ; Bornstein, S.R. ; Lenders, J.W. ; Willenberg, H.S. ; Eisenhofer, G. Plasma metanephrine for assessing the selectivity of adrenal venous sampling. Hypertension 62, 1152-1157 (2013)

Döcke, S. ; Lock, J.F. ; Birkenfeld, A.L. ; Hoppe, S. ; Lieske, S. ; Rieger, A. ; Raschzok, N. ; Sauer, I.M. ; Florian, S. ; Osterhoff, M.A. ; Heller, R. ; Herrmann, K. ; Lindenmüller, S. ; Horn, P. ; Bauer, M. ; Weickert, M.O. ; Neuhaus, P. ; Stockmann, M. ; Möhlig, M. ; Pfeiffer, A.F. ; von Loeffelholz, C. Elevated hepatic chemerin mRNA expression in human non-alcoholic fatty liver disease. Eur. J. Endocrinol. 169, 547-557 (2013)

Eugster, A. ; Lindner, A. ; Heninger, A.K. ; Wilhelm, C. ; Dietz, S. ; Ziegler, A.-G. ; Bonifacio, E. Measuring T cell receptor and T cell gene expression diversity in antigen-responsive human CD4+ T cells. J. Immunol. Methods 400-401, 13-22 (2013)

Ferraz, C. ; Lorenz, S. ; Wojtas, B. ; Bornstein, S.R. ; Paschke, R. ; Eszlinger, M. Inverse correlation of miRNA and cell cycle-associated genes suggests influence of miRNA on benign thyroid nodule tumorigenesis. J. Clin. Endocrinol. Metab. 98, 8-16 (2013)

Franke, K. ; Kalucka, J. ; Mamlouk, S. ; Singh, R.P. ; Muschter, A. ; Weidemann, A. ; Iyengar, V. ; Jahn, S. ; Wieczorek, K. ; Geiger, K. ; Muders, M.H. ; Sykes, A.M. ; Poitz, D.M. ; Ripich, T. ; Otto, T. ; Bergmann, S. ; Breier, G. ; Baretton, G. ; Fong, G.H. ; Greaves, D.R. ; Bornstein, S. ; Chavakis, T. ; Fandrey, J. ; Gassmann, M. ; Wielockx, B. HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis. Blood 121, 1436-1445 (2013)

Gavalas, A. ; Lan, T.H. ; Liu, Q. ; Corrêa, I.R. ; Javitch, J.A. ; Lambert, N.A. Segregation of family A G protein-coupled receptor protomers in the plasma membrane. Mol. Pharmacol. 84, 346-352 (2013)

Graessler, J. ; Qin, Y. ; Zhong, H. ; Zhang, J. ; Licinio, J. ; Wong, M.L. ; Xu, A. ; Chavakis, T. ; Bornstein, A.B. ; Ehrhart-Bornstein, M. ; Lamounier-Zepter, V. ; Lohmann, T. ; Wolf, T. ; Bornstein, S.R. Metagenomic sequencing of the human gut microbiome before and after bariatric surgery in obese patients with type 2 diabetes: Correlation with inflammatory and metabolic parameters. Pharmacogenomics J. 13, 514-522 (2013)

Gräßler, J. ; Blüher, M. ; Chavakis, T. Adipositas und Inflammation. Dtsch. Med. Wochenschr. 138, 172-175 (2013)

Gräßler, J. ; Kopprasch, S. ; Passauer, J. ; Fischer, S. ; Schuhmann, K. ; Bergmann, S. ; Siegert, G. ; Shevchenko, A. ; Bornstein, S.R. ; Julius, U. Differential effects of lipoprotein apheresis by lipidfiltration or dextran sulfate adsorption on lipidomic profile. Atherosclerosis 14, 151-155 (2013)

Hajishengallis, G. ; Chavakis, T. Endogenous modulators of inflammatory cell recruitment. Trends Immunol. 34, 1-6 (2013)

Haufe, S. ; Haas, V. ; Utz, W. ; Birkenfeld, A.L. ; Jeran, S. ; Böhnke, J. ; Mähler, A. ; Luft, F.C. ; Schulz-Menger, J. ; Boschmann, M. ; Jordan, J. ; Engeli, S. Long-lasting improvements in liver fat and metabolism despite body weight regain after dietary weight loss. Diabetes Care 36, 3786-3792 (2013)

Heninger, A.K. ; Monti, P. ; Wilhelm, C. ; Schwaiger, P. ; Kuehn, D. ; Ziegler, A.-G. ; Bonifacio, E. Activation of islet autoreactive naive T cells in infants is influenced by homeostatic mechanisms and antigen presenting capacity. Diabetes 62, 2059-2066 (2013)

Hohenstein, B. ; Bornstein, S.R. ; Aringer, M. Immunoadsorption for connective tissue disease. Atherosclerosis 14, 185-189 (2013)

Ilegems, E. ; Dicker, A. ; Speier, S. ; Sharma, A. ; Bahow, A. ; Edlund, P.K. ; Leibiger, I.B. ; Berggren, P.O. Reporter islets in the eye reveal the plasticity of the endocrine pancreas. Proc. Natl. Acad. Sci. U.S.A. 110, 20581-20586 (2013)

Ioannou, M. ; Serafimidis, I. ; Arnes, L. ; Sussel, L. ; Singh, S. ; Vasiliou, V. ; Gavalas, A. ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools. Dev. Biol. 374, 153-163 (2013)

Ivanova, A. ; Kalaidzidis, Y. ; Dirkx, R. ; Sarov, M. ; Gerlach, M. ; Schroth-Diez, B. ; Müller, A. ; Liu, Y. ; Andree, C. ; Mulligan, B. ; Münster, C. ; Kurth, T. ; Bickle, M. ; Speier, S. ; Anastassiadis, K. ; Solimena, M. Age-dependent labeling and imaging of insulin secretory granules. Diabetes 62, 3687-3696 (2013)

Julius, U. ; Taseva, K. ; Fischer, S. ; Passauer, J. ; Bornstein, S.R. Current situation of lipoprotein apheresis in Saxony. Atherosclerosis 14, 51-55 (2013)

Kanczkowski, W. ; Alexaki, V.I. ; Tran, N. ; Großklaus, S. ; Zacharowski, K. ; Martinez, A. ; Popovics, P. ; Block, N.L. ; Chavakis, T. ; Schally, A.V. ; Bornstein, S.R. Hypothalamo-pituitary and immune-dependent adrenal regulation during systemic inflammation. Proc. Natl. Acad. Sci. U.S.A. 110, 14801-14806 (2013)

Kanczkowski, W. ; Chatzigeorgiou, A. ; Grossklaus, S. ; Sprott, D. ; Bornstein, S.R. ; Chavakis, T. Role of the endothelial-derived endogenous anti-inflammatory factor Del-1 in inflammation-mediated adrenal gland dysfunction. Endocrinology 154, 1181-1189 (2013)

Kanczkowski, W. ; Chatzigeorgiou, A. ; Samus, M. ; Tran, N. ; Zacharowski, K. ; Chavakis, T. ; Bornstein, S.R. Characterization of the LPS-induced inflammation of the adrenal gland in mice. Mol. Cell. Endocrinol. 371, 228-235 (2013)

Klotzsche-von Ameln, A. ; Prade, I. ; Grosser, M. ; Kettelhake, A. ; Rezaei, M. ; Chavakis, T. ; Flamme, I. ; Wielockx, B. ; Breier, G. PHD4 stimulates tumor angiogenesis in osteosarcoma cells via TGF-α. Mol. Cancer Res. 11, 1337-1348 (2013)

Kopprasch, S. ; Bornstein, S.R. ; Schwarz, P.E. ; Bergmann, S. ; Julius, U. ; Graessler, J. Single whole blood dextran sulfate adsorption favorably affects systemic oxidative balance in lipoprotein apheresis patients. Atherosclerosis 14, 157-160 (2013)

Korten, S. ; Brunssen, C. ; Poitz, D.M. ; Großklaus, S. ; Brux, M. ; Schnittler, H.J. ; Strasser, R.H. ; Bornstein, S.R. ; Morawietz, H. ; Goettsch, W. Impact of Hey2 and COUP-TFII on genes involved in arteriovenous differentiation in primary human arterial and venous endothelial cells. Basic Res. Cardiol. 108:362 (2013)

Krautz, C. ; Wolk, S. ; Steffen, A. ; Knoch, K.P. ; Ceglarek, U. ; Thiery, J. ; Bornstein, S. ; Saeger, H.-D. ; Solimena, M. ; Kersting, S. Effects of immunosuppression on alpha and beta cell renewal in transplanted mouse islets. Diabetologia 56, 1596-1604 (2013)

Kumashiro, N. ; Beddow, S.A. ; Vatner, D.F. ; Majumdar, S.K. ; Cantley, J.L. ; Guebre-Egziabher, F. ; Fat, I. ; Guigni, B. ; Jurczak, M.J. ; Birkenfeld, A.L. ; Kahn, M. ; Perler, B.K. ; Puchowicz, M.A. ; Manchem, V.P. ; Bhanot, S. ; Still, C.D. ; Gerhard, G.S. ; Petersen, K.F. ; Cline, G.W. ; Shulman, G.I. ; Samuel, V.T. Targeting pyruvate carboxylase reduces gluconeogenesis and adiposity and improves insulin resistance. Diabetes 62, 2183-2194 (2013)

Lamounier-Zepter, V. ; Look, C. ; Ehrhart-Bornstein, M. ; Bornstein, S.R. ; Fischer, S. ; Julius, U. Lipoprotein apheresis reduces adipocyte fatty acid-binding protein serum levels. Atherosclerosis 14, 129-134 (2013)

Langer, H.F. ; Chavakis, T. Platelets and neurovascular inflammation. Thromb. Haemost. 110, 888-893 (2013)

Lee, H.S. ; Briese, T. ; Winkler, C. ; Rewers, M. ; Bonifacio, E. ; Hyoty, H. ; Pflueger, M. ; Simell, O. ; She, J.X. ; Hagopian, W. ; Lernmark, A. ; Akolkar, B. ; Krischer, J.P. ; Ziegler, A.-G. ; TEDDY Study Group Next-generation sequencing for viruses in children with rapid-onset type 1 diabetes. Diabetologia 56, 1705-1711 (2013)

Leinster, D.A. ; Colom, B. ; Whiteford, J.R. ; Ennis, D.P. ; Lockley, M. ; McNeish, I.A. ; Aurrand-Lions, M. ; Chavakis, T. ; Imhof, B.A. ; Balkwill, F.R. ; Nourshargh, S. Endothelial cell junctional adhesion molecule C plays a key role in the development of tumors in a murine model of ovarian cancer. FASEB J. 27, 4244-4253 (2013)

Lin, Z. ; Tian, H. ; Lam, K.S. ; Lin, S. ; Hoo, R.C. ; Konishi, M. ; Itoh, N. ; Wang, Y. ; Bornstein, S.R. ; Xu, A. ; Li, X. Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice. Cell Metab. 17, 779-789 (2013)

Löffler, M.G. ; Birkenfeld, A.L. ; Philbrick, K.M. ; Belman, J.P. ; Habtemichael, E.N. ; Booth, C.J. ; Castorena, C.M. ; Choi, C.S. ; Jornayvaz, F.R. ; Gassaway, B.M. ; Lee, H.Y. ; Cartee, G.D. ; Philbrick, W. ; Shulman, G.I. ; Samuel, V.T. ; Bogan, J.S. Enhanced fasting glucose turnover in mice with disrupted action of TUG protein in skeletal muscle. J. Biol. Chem. 288, 20135-20150 (2013)

Ludwig, B. ; Reichel, A. ; Steffen, A. ; Zimerman, B. ; Schally, A.V. ; Block, N.L. ; Colton, C.K. ; Ludwig, S. ; Kersting, S. ; Bonifacio, E. ; Solimena, M. ; Gendler, Z. ; Rotem, A. ; Barkai, U. ; Bornstein, S.R. Transplantation of human islets without immunosuppression. Proc. Natl. Acad. Sci. U.S.A. 110, 19054-19058 (2013)

Magro, M.G. ; Solimena, M. Regulation of β-cell function by RNA-binding proteins. Mol. Metab. 2, 348-355 (2013)

Maliga, Z. ; Junqueira, M. ; Toyoda, Y. ; Ettinger, A. ; Mora-Bermudez, F. ; Klemm, R.W. ; Vasilj, A. ; Guhr, E. ; Ibarlucea-Benitez, I. ; Poser, I. ; Bonifacio, E. ; Huttner, W.B. ; Shevchenko, A. ; Hyman, A.A. A genomic toolkit to investigate kinesin and myosin motor function in cells. Nat. Cell Biol. 15, 325-334 (2013)

Marciniak, A. ; Selck, C. ; Friedrich, B. ; Speier, S. Mouse pancreas tissue slice culture facilitates long-term studies of exocrine and endocrine cell physiology in situ. PLoS ONE 8:e78706 (2013)

Monti, P. ; Brigatti, C. ; Krasmann, M. ; Ziegler, A.-G. ; Bonifacio, E. Concentration and activity of the soluble form of the interleukin-7 receptor α in type I diabetes identifies an interplay between hyperglycemia and immune function. Diabetes 62, 2500-2508 (2013)

Morawietz, H. ; Goettsch, W. ; Brux, M. ; Reimann, M. ; Bornstein, S.R. ; Julius, U. ; Ziemssen, T. Lipoprotein apheresis of hypercholesterolemic patients mediates vasoprotective gene expression in human endothelial cells. Atherosclerosis 14, 107-113 (2013)

Müller, G. ; Parfentyeva, E. ; Olschewsky, J. ; Bornstein, S.R. ; Schwarz, P.E. Assessment of small fiber neuropathy to predict future risk of type 2 diabetes. Prim. Care Diabetes 7, 269-273 (2013)

Müller, G. ; Weser, G. ; Schwarz, P.E. The European perspective of diabetes prevention: The need for individualization of diabetes prevention. J. Endocrinol. Invest. 36, 352-357 (2013)

Neufeld, T.P. ; Ludwig, B. ; Barkai, U. ; Weir, G.C. ; Colton, C.K. ; Evron, Y. ; Balyura, M. ; Yavriyants, K. ; Zimermann, B. ; Azarov, D. ; Maimon, S. ; Shabtay, N. ; Rozenshtein, T. ; Lorber, D. ; Steffen, A. ; Willenz, U. ; Bloch, K. ; Vardi, P. ; Taube, R. ; de Vos, P. ; Lewis, E.C. ; Bornstein, S.R. ; Rotem, A. The efficacy of an immunoisolating membrane system for islet xenotransplantation in minipigs. PLoS ONE 8:e70150 (2013)

Ninov, N. ; Hesselson, D. ; Gut, P. ; Zhou, A. ; Fidelin, K. ; Stainier, D.Y. Metabolic regulation of cellular plasticity in the pancreas. Curr. Biol. 23, 1242-1250 (2013)

Palm, W. ; Swierczynska, M.M. ; Kumari, V. ; Ehrhart-Bornstein, M. ; Bornstein, S.R. ; Eaton, S. Secretion and signaling activities of lipoprotein-associated hedgehog and non-sterol-modified hedgehog in flies and mammals. PLoS Biol. 11:e1001505 (2013)

Pamporaki, C. ; Därr, R. ; Bursztyn, M. ; Glöckner, S. ; Bornstein, S.R. ; Lenders, J.W. ; Pacak, K. ; Krinner, A. ; Eisenhofer, G. Plasma-free vs deconjugated metanephrines for diagnosis of phaeochromocytoma. Clin. Endocrinol. 79, 476-483 (2013)

Petrowski, K. ; Wintermann, G.B. ; Schaarschmidt, M. ; Bornstein, S.R. ; Kirschbaum, C. Blunted salivary and plasma cortisol response in patients with panic disorder under psychosocial stress. Int. J. Psychophysiol. 88, 35-39 (2013)

Petzold, C. ; Riewaldt, J. ; Watts, D. ; Sparwasser, T. ; Schallenberg, S. ; Kretschmer, K. Foxp3+ regulatory T cells in mouse models of type 1 diabetes. J. Diabetes Res. 2013:940710 (2013)

Phieler, J. ; Chung, K.-J. ; Chatzigeorgiou, A. ; Klotzsche-von Ameln, A. ; Garcia-Martin, R. ; Sprott, D. ; Moisidou, M. ; Tzanavari, T. ; Ludwig, B. ; Baraban, E. ; Ehrhart-Bornstein, M. ; Bornstein, S.R. ; Mziaut, H. ; Solimena, M. ; Karalis, K.P. ; Economopoulou, M. ; Lambris, J.D. ; Chavakis, T. The complement anaphylatoxin C5a receptor contributes to obese adipose tissue inflammation and insulin resistance. J. Immunol. 191, 4367-4374 (2013)

Phieler, J. ; Garcia-Martin, R. ; Lambris, J.D. ; Chavakis, T. The role of the complement system in metabolic organs and metabolic diseases. Semin. Immunol. 25, 47-53 (2013)

Piemonti, L. ; Everly, M.J. ; Maffi, P. ; Scavini, M. ; Poli, F. ; Nano, R. ; Cardillo, M. ; Melzi, R. ; Mercalli, A. ; Sordi, V. ; Lampasona, V. ; Espadas de Arias, A. ; Scalamogna, M. ; Bosi, E. ; Bonifacio, E. ; Secchi, A. ; Terasaki, P.I. Alloantibody and autoantibody monitoring predicts islet transplantation outcome in human type 1 diabetes. Diabetes 62, 1656-1664 (2013)

Reichel, A. ; Rietzsch, H. ; Ludwig, B. ; Röthig, K. ; Moritz, A. ; Bornstein, S.R. Self-adjustment of insulin dose using graphically depicted self-monitoring of blood glucose measurements in patients with type 1 diabetes mellitus. J. Diabetes Sci. Technol. 7, 156-162 (2013)

Reimann, M. ; Julius, U. ; Bornstein, S.R. ; Fischer, S. ; Reichmann, H. ; Rüdiger, H. ; Ziemssen, T. Regular lipoprotein apheresis maintains residual cardiovascular and microvascular function in patients with advanced atherosclerotic disease. Atherosclerosis 14, 135-141 (2013)

Ringers, J. ; van der Torren, C.R. ; van de Linde, P. ; van der Boog, P.J. ; Mallat, M.J. ; Bonifacio, E. ; Roep, B.O. ; de Fijter, J.W. Pretransplantation GAD-autoantibody status to guide prophylactic antibody induction therapy in simultaneous pancreas and kidney transplantation. Transplantation 96, 745-752 (2013)

Ritter, P.S. ; Kretschmer, K. ; Pfennig, A. ; Soltmann, B. Disturbed sleep in bipolar disorder is related to an elevation of IL-6 in peripheral monocytes. Med. Hypotheses 81, 1031-1033 (2013)

Saha, S. ; Graessler, J. ; Bornstein, S.R. ; Schwarz, P.E. ; Kopprasch, S. Stimulation of phagocyte adhesion to endothelial cells by modified VLDL and HDL requires scavenger receptor BI. Mol. Cell. Biochem. 383, 21-28 (2013)

Saha, S. ; Schwarz, P.E. ; Bergmann, S. ; Bornstein, S.R. ; Graessler, J. ; Kopprasch, S. Circulating very-low-density lipoprotein from subjects with impaired glucose tolerance accelerates adrenocortical cortisol and aldosterone synthesis. Horm. Metab. Res. 45, 169-172 (2013)

Schatz, U. ; Arneth, B. ; Siegert, G. ; Siegels, D. ; Fischer, S. ; Julius, U. ; Bornstein, S.R. Iron deficiency and its management in patients undergoing lipoprotein apheresis. Comparison of two parenteral iron formulations. Atherosclerosis 14, 115-122 (2013)

Schöfl, C. ; Franz, H. ; Grussendorf, M. ; Honegger, J. ; Jaursch-Hancke, C. ; Mayr, B. ; Schopohl, J. Long-term outcome in patients with acromegaly: Analysis of 1344 patients from the German Acromegaly Register. Eur. J. Endocrinol. 168, 39-47 (2013)

Schubert, U. ; Schmid, J. ; Lehmann, S. ; Zhang, X.Y. ; Morawietz, H. ; Block, N.L. ; Kanczkowski, W. ; Schally, A.V. ; Bornstein, S.R. ; Ludwig, B. Transplantation of pancreatic islets to adrenal gland is promoted by agonists of growth-hormone-releasing hormone. Proc. Natl. Acad. Sci. U.S.A. 110, 2288-2293 (2013)

Schwarz, P.E. ; Gallein, G. ; Ebermann, D. ; Müller, A. ; Lindner, A. ; Rothe, U. ; Nebel, I.T. ; Müller, G. Global Diabetes Survey - an annual report on quality of diabetes care. Diabetes Res. Clin. Pract. 100, 11-18 (2013)

Shin, J.T. ; Hosur, K.B. ; Pyaram, K. ; Jotwani, R. ; Liang, S. ; Chavakis, T. ; Hajishengallis, G. Expression and function of the homeostatic molecule Del-1 in endothelial cells and the periodontal tissue. Clin. Dev. Immunol. 2013:617809 (2013)

Singh, R.P. ; Franke, K. ; Kalucka, J. ; Mamlouk, S. ; Muschter, A. ; Gembarska, A. ; Grinenko, T. ; Willam, C. ; Naumann, R. ; Anastassiadis, K. ; Stewart, A.F. ; Bornstein, S.R. ; Chavakis, T. ; Breier, G. ; Waskow, C. ; Wielockx, B. HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress. Blood 121, 5158-5166 (2013)

Stalder, T. ; Kirschbaum, C. ; Alexander, N. ; Bornstein, S.R. ; Gao, W. ; Miller, R. ; Stark, S. ; Bosch, J.A. ; Fischer, J.E. Cortisol in hair and the metabolic syndrome. J. Clin. Endocrinol. Metab. 98, 2573-2580 (2013)

Sturm, D. ; Marselli, L. ; Ehehalt, F. ; Richter, D. ; Distler, M. ; Kersting, S. ; Grützmann, R. ; Bokvist, K. ; Froguel, P. ; Liechti, R. ; Jörns, A. ; Meda, P. ; Baretton, G.B. ; Saeger, H.-D. ; Schulte, A.M. ; Marchetti, P. ; Solimena, M. Improved protocol for laser microdissection of human pancreatic islets from surgical specimens. J. Vis. Exp. 71:e50231 (2013)

Swierczynska, M.M. ; Lamounier-Zepter, V. ; Bornstein, S.R. ; Eaton, S. Lipoproteins and Hedgehog signalling - possible implications for the adrenal gland function. Eur. J. Clin. Invest. 43, 1178-1183 (2013)

Taseva, K. ; Fischer, S. ; Passauer, J. ; Weiss, N. ; Bornstein, S.R. ; Julius, U. Factors inducing cardiovascular events in patients treated by lipoprotein apheresis. Atherosclerosis 14, 45-50 (2013)

Tausche, A.K. ; Gehrisch, S. ; Panzner, I. ; Winzer, M. ; Range, U. ; Bornstein, S.R. ; Siegert, G. ; Wunderlich, C. ; Aringer, M. A 3-day delay in synovial fluid crystal identification did not hinder the reliable detection of monosodium urate and calcium pyrophosphate crystals. J. Clin. Rheumatol. 19, 241-245 (2013)

Toker, A. ; Engelbert, D. ; Garg, G. ; Polansky, J.K. ; Floess, S. ; Miyao, T. ; Baron, U. ; Düber, S. ; Geffers, R. ; Giehr, P. ; Schallenberg, S. ; Kretschmer, K. ; Olek, S. ; Walter, J. ; Weiss, S. ; Hori, S. ; Hamann, A. ; Huehn, J. Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus. J. Immunol. 190, 3180-3188 (2013)

Toporkiewicz, M. ; Grzybek, M. ; Meissner, J. ; Michalczyk, I. ; Dubielecka, P.M. ; Korycka, J. ; Seweryn, E. ; Sikorski, A.F. Release of an ~55kDa fragment containing the actin-binding domain of β-spectrin by caspase-8 during FND-induced apoptosis depends on the presence of protein 4.1. Arch. Biochem. Biophys. 535, 205-213 (2013)

Tsourdi, E. ; Barthel, A. ; Rietzsch, H. ; Reichel, A. ; Bornstein, S.R. Current aspects in the pathophysiology and treatment of chronic wounds in diabetes mellitus. Biomed Res. Int. 2013:385641 (2013)

Ullmann, E. ; Barthel, A. ; Licinio, J. ; Petrowski, K. ; Bornstein, S.R. ; Strauß, B. Increased rate of depression and psychosomatic symptoms in Jewish migrants from the post-Soviet-Union to Germany in the 3rd generation after the Shoa. Transl. Psychiatry 3:e241 (2013)

von Dryander, M. ; Fischer, S. ; Passauer, J. ; Müller, G. ; Bornstein, S.R. ; Julius, U. Differences in the atherogenic risk of patients treated by lipoprotein apheresis according to their lipid pattern. Atherosclerosis 14, 39-44 (2013)

Willmes, D.M. ; Birkenfeld, A.L. The role of INDY in metabolic regulation. Comp. Struc. Biotech. J. 6:e201303020 (2013)

Ziegler, A.-G. ; Rewers, M. ; Simell, O. ; Simell, T. ; Lempainen, J. ; Steck, A. ; Winkler, C. ; Ilonen, J. ; Veijola, R. ; Knip, M. ; Bonifacio, E. ; Eisenbarth, G.S. Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children. JAMA 309, 2473-2479 (2013)

Ziegler, C.G. ; Ullrich, M. ; Schally, A.V. ; Bergmann, R. ; Pietzsch, J. ; Gebauer, L. ; Gondek, K. ; Qin, N. ; Pacak, K. ; Ehrhart-Bornstein, M. ; Eisenhofer, G. ; Bornstein, S.R. Anti-tumor effects of peptide analogs targeting neuropeptide hormone receptors on mouse pheochromocytoma cells. Mol. Cell. Endocrinol. 371, 189-194 (2013)