Jiajie Chen

2025

• Jiajie Chen^#, Yitong Wang^#, Zhibo Yang^#, Kai Tang, Xinchun Liu, Hongshi Ma, Huamao Ye*, Chengtie Wu*, Yufang Zhu*. A Coordination Nanosystem Enables Endogenous Ferric Ion-Initiated Multi-Catalysis for Synergistic Tumor-Specific Ferroptosis and Gene Therapy. Small 2025, 21, 2411440.
• Xinxin Zhang, Jimin Huang, Jinzhou Huang, Zhe Shi, Huicong Niu, Yi Zheng, Xiao Wang, Chengtie Wu, Jiajie Chen*, Ping Liu,* Yufang Zhu*. A Hydrogel Engineered with Semiconductive MnPSe₃ Nanosheets as an Integrative Sonosensitizer/Fenton-Like Catalyst/Nutrient for Melanoma Postoperative Care. Adv. Funct. Mater. 2025, 35, 2417871.

2024

• Jiajie Chen^#, Yitong Wang^#, Jian Huang^#, Zhibo Yang, Huicong Niu, Xiaolian Su, Jimin Huang, Hongshi Ma, Yufang Zhu*, Chengtie Wu*, Jianlin Shi*. Cascade specific endogenous Fe³⁺ interference and in situ catalysis for tumor therapy with stemness suppression. Natl. Sci. Rev. 2024, nwae434.
• Yinghui Wang^#, Jiajie Chen^#, Chengtie Wu, Yufang Zhu*. Nanoscale porphyrinic metal–organic frameworks as a photodynamic probe for highly sensitive detection of SARS-CoV-2 related RNA. Sensor. Actuat. B-Chem. 2024, 406: 135413.

2023

• Jiajie Chen, Yufang Zhu*, Chengtie Wu, Jianlin Shi*. Engineering lactate-modulating nanomedicines for cancer therapy. Chem. Soc. Rev. 2023, 52: 973.
• Jiajie Chen, Yinghui Wang, Chengtie Wu, Yin Xiao*, Yufang Zhu*. A coronavirus-mimic mesoporous silica nanosystem enables efficient targeted delivery of siRNA for anti-SARS-CoV-2. Appl. Mater. Today 2023, 35: 101952.

2022

• Jiajie Chen^#, Yi Cao^#, Shiyang Lin, Huicong Niu, Hongjian Zhang, Lei Guan, Chaoqin Shu, Aijun Wu, Yuhai Bian*, Yufang Zhu*. A responsive microneedle system for efficient anti-melanoma by combining self-enhanced chemodynamic therapy with photothermal therapy. Chem. Eng. J. 2022, 431: 133466.
• Jiajie Chen^#, Huicong Niu^#, Lei Guan, Zhibo Yang, Yuzhao He, Jinjin Zhao, Chengtie Wu, Yitong Wang*, Kaili Lin*, and Yufang Zhu*. Microneedle-Assisted Transdermal Delivery of 2D Bimetallic Metal–Organic Framework Nanosheet-Based Cascade Biocatalysts for Enhanced Catalytic Therapy of Melanoma. Adv. Healthc. Mater. 2022, 12: 2202474.
• Huicong Niu^#, Jiajie Chen^#, Jie Jin, Xuejiao Qi, Kaixuan Bai, Chaoqin Shu, Aijun Wu, Yin Xiao, Chengtie Wu, Hui Bu*, Yufang Zhu*. Engineering metalloporphyrin-integrated nanosystems for targeted sono-/chemo- dynamic therapy of leptomeningeal carcinomatosis through intrathecal administration. Chem. Eng. J. 2022, 437: 135373.
• Shiyang Lin^#, Mai Yang^#, Jiajie Chen^#, Wei Feng*, Yu Chen*, Yufang Zhu*. Two-Dimensional FePS₃ Nanosheets as an Integrative Sonosensitizer/Nanocatalyst for Efficient Nanodynamic Tumor Therapy. Small 2022, 19: 2204992.

2021

• Jiajie Chen, Yufang Zhu*, Stefan Kaskel*. Porphyrin-Based Metal–Organic Frameworks for Biomedical Applications. Angew. Chem. Int. Ed. 2021, 60: 5010-5035.
• Jiajie Chen, Shiyang Lin, Doudou Zhao, Lei Guan, Yaping Hu, Yitong Wang*, Kaili Lin*, Yufang Zhu*. Palladium Nanocrystals-Engineered Metal–Organic Frameworks for Enhanced Tumor Inhibition by Synergistic Hydrogen/Photodynamic Therapy. Adv. Funct. Mater. 2021, 31: 2006853.
• Jiajie Chen^#, Yitong Wang^#, Huicong Niu, Yuwei Wang, Aijun Wu, Chaoqin Shu, Yufang Zhu*, Yuhai Bian*, Kaili Lin*. Metal–Organic Framework-Based Nanoagents for Effective Tumor Therapy by Dual Dynamics-Amplified Oxidative Stress. ACS Appl. Mater. Interfaces 2021, 13: 45201-45213.

2020

• Jiajie Chen, Yufang Zhu*, Chengtie Wu, Jianlin Shi*. Nanoplatform-based cascade engineering for cancer therapy. Chem. Soc. Rev. 2020, 49: 9057-9094.
• Jiajie Chen^#, Yitong Wang^#, Baoyuan Ma^#, Lei Guan, Zhengfang Tian, Kaili Lin*, Yufang Zhu*. Biodegradable hollow mesoporous organosilica-based nanosystems with dual stimuli-responsive drug delivery for efficient tumor inhibition by synergistic chemo- and photothermal therapy. Appl. Mater. Today 2020, 19: 100655.

2019

• Jiajie Chen^#, Jiaxing Liu^#, Yaping Hu, Zhengfang Tian, Yufang Zhu*. Metal–organic framework-coated magnetite nanoparticles for synergistic magnetic hyperthermia and chemotherapy with pH-triggered drug release. Sci. Technol. Adv. Mater. 2019, 20: 1043-1054.