B CUBE Microscopy

AFM: JPK Nanowizard 4 setup of the MIM Facility at B CUBE — © Jens Ehrig

LUMICKS C-Trap Optical Tweezers setup of the MIM Facility at B CUBE — © Jens Ehrig

The Nikon Ti-E TIRF/FRAP setup of the MIM Facility at B CUBE — © Jens Ehrig

AFM topography scan of a diatom valve carried out at the JPK NanoWizard4 of the MIM Facility at B CUBE.

The B CUBE microscopy facility offers users access to a range of microscopy techniques to identify and characterize the relationship between structure and function at the molecular level.

In the field of imaging, this includes atomic force microscopy (AFM) and optical microscopy, with techniques such as super-resolution single molecule localization microscopy (SMLM, e.g. STORM/PALM/...), total internal reflection fluorescence microscopy (TIRF), confocal spinning disk microscopy, and ordinary epifluorescence microscopy. Single-molecule techniques such as single-particle tracking (SPT), Förster resonance energy transfer (FRET) are offered together with the necessary expertise for analysis.