Research projects

P1 Targeting the CX3CL1/CX3CR1 axis to attenuate neutrophil infiltration early after myocardial infarction 

Applicants: Ali El-Armouche, Erik Klapproth

P2 Macrophage ferroptosis in myocardial infarction 

Applicants: Maria Fedorova, Andreas Linkermann, Wulf Tonnus

P3 The role of clonal hematopoiesis driven by DNMT3A mutations in regulating innate immune cell functions in the context of myocardial infarction 

Applicants: Triantafyllos Chavakis, Lydia Kalafati

P4 Metabolic reprograming of sexually dimorphic macrophage responses after myocardial infarction 

Applicants: Vasileia Ismini Alexaki, Mario Schubert

P5 Myeloid HIF Signaling as a Therapeutic Target in Post-Infarct Inflammation and Repair 

Applicants: Peter Mirtschink, Ben Wielockx

P6 Impact of sympathetic activation and exercise training on innate immune cell phenotypes after myocardial infarction 

Applicants: Susanne Kämmerer, Axel Linke

P7 Cell-based therapeutic strategies to invigorate resident cardiac macrophages 

Applicants: Irakli Kopaliani, Michael Sieweke

P8 Microfluidic organ-on-a-chip system: Unravelling the function and therapeutic potential of macrophages in ischemia-reperfusion injury 

Applicant: Kaomei Guan

PZ1 Experimental models of myocardial infarction, phenotyping and immune-metabolic characterisation of patients with acute MI 

Applicants: Ali El-Armouche, Kaomei Guan, Peter Mirtschink

PZ2 Biosample management, data management, and integrative data science 

Applicants: Heidi Altmann, Axel Linke, Josch Pauling