Publications

Selected Publications

2018

Kindt ASD, Fuerst RW, Knoop J, Laimighofer M, Telieps T, Hippich M, Woerheide
MA, Wahl S, Wilson R, Sedlmeier EM, Hommel A, Todd JA, Krumsiek J, Ziegler AG,
Bonifacio E. Allele-specific methylation of type 1 diabetes susceptibility
genes. J Autoimmun. 2018;89:63-74

2017

Heninger A-K, Eugster A, Kuehn D, Buettner F, Kuhn M, Lindner A, Dietz S, Jergens S, WIlhelm C, Beyerlein A, Ziegler A-G, Bonifacio E. A divergent population of autoantigen-responsive CD4+ T cells in infants prior to β cell autoimmunity. Science Translational Medicine. 2017; 378 (9)

2015

Bonifacio E, Ziegler A-G, Klingensmith G, Schober E, Bingley PJ, Rottenkolber M, Theil A, Eugster A, Puff R, Peplow C, Buettner F, Lange K, Eisenbarth G, Hasford J, Achenbach P. Effects of high dose oral insulin on immune responses in children at high risk for type 1 diabetes: the Pre-POINT randomized clinical trial. JAMA. 2015; 313(15):1541-9

Bonifacio E. Predicting type 1 diabetes using biomarkers. Diabetes Care. 2015;38(6):989-96

Eugster A, Lindner A, Catani M, Heninger AK, Dahl A, Klemroth S, Kühn D, Dietz S, Bickle M, Ziegler AG, Bonifacio E. High Diversity in the TCR Repertoire of GAD65 Autoantigen-Specific Human CD4+ T Cells. J Immunol. 2015; 194(6):2531-8

Eugster A, Lindner A, Catani M, Heninger AK, Dahl A, Klemroth S, Kühn D,
Dietz S, Bickle M, Ziegler AG, Bonifacio E. High diversity in the TCR repertoire
of GAD65 autoantigen-specific human CD4+ T cells. J Immunol. 2015; 194(6):2531-8

2013

Ziegler AG, Rewers M, Simell O, Simell T, Lempainen J, Steck A, Winkler C, Ilonen J, Veijola R, Knip M, Bonifacio E, Eisenbarth GS. Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children. JAMA. 2013;309(23):2473-9

Heninger AK, Monti P, Wilhelm C, Schwaiger P, Kuehn D, Ziegler AG, Bonifacio E. Activation of islet autoreactive naïve T cells in infants is influenced by homeostatic mechanisms and antigen presenting capacity. Diabetes.2013; 62(6):2059-66