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Kretschmer Group

In a healthy organism, regulatory T (Treg) cells expressing the transcription factor Foxp3 suppress fatal immune responses against self, thereby preventing catastrophic autoimmunity. Understanding the biology of Foxp3+ Treg cells will help to harness their potent suppressor function against unwanted immune responses underlying autoimmune diseases or the destruction of transplanted hematopoietic stem cells.

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Prof. Dr. Karsten Kretschmer