New generation of 3D scaffolds for patient-specific therapies in orthopedic applications

Projektleiter:                          Prof. Dr. Michael Gelinsky

Projektbearbeiterin:             Dr. Vera Guduric

Kooperationspartner:          Prof. Dr. Chengtie Wu, Shanghai Institute of Ceramics, P. R.   China

Projektlaufzeit:                     1. 10. 2018 – 30. 11. 2021

Projektbeschreibung:

In recent years, several additive manufacturing techniques like 3D plotting has been translated to the biomedical field and applied successfully for the generation of implants or tissue engineering scaffolds e. g. for bone repair, since it allows for highly tunable inner and outer geometry. In clinical practice, however, the repair of a bone defect is frequently associated with patient-specific demands on the implant. Addressing these challenges, the principle aim of the project is to develop a modular system, consisting of therapeutic bioceramics as a “tool box” and 3D plotting techniques as an “organizer”, based on the concept that their combination will enable for the tailored design, fabrication and biofunctionalization of patient-specific 3D-plotting implants. In the binational research project, the design of therapeutic bioceramics by incorporation of biologically active metal ions and application of advanced 3D plotting techniques for the fabrication of highly controllable architectures are investigated.