Applied Bioinformatics
The course teaches the concepts and algorithms underlying sequence comparison and their applications in sequence and to some degree in structure analysis. After a brief introduction, the basic Levenshtein distance is successively modified to compute the longest common subsequence, alignments, to include substitution matrices, local alignments, refined scoring schemes, and fast algorithms. Next, multiple sequence alignments are covered and the computation of phylogenetic trees. Finally, multiple sequence alignments and phylogenetic trees are used conceptually to tackle 3D structure prediction with co-evolution data.
You will find the lecture schedule and all relevant information and material in the OPAL course once you registered yourself there.
If you want to join the course as an extra module or as a computer science student (Master/Diplom Informatik, Modul INF-PM-ANW), please contact ab_teachers@lists.biotec.tu-dresden.de