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Stewart Group

Our work focuses on two complementary aspects of genomics,
(I) mechanisms of epigenetic regulation in mammalian development and homeostasis;
(II) technologies of genetic engineering.

learn more Stewart Group

Fluorescent stained intestinal organoid © Neha Goveas
Research

Our experimental approach to unravelling epigenetic mechanisms and hierarchies is based on engineering the mouse genome.
The pictures shows a man who is A. Francis Stewart © Michael Kretzschmar
Group Leader

Prof. A. Francis Stewart
Stewart Lab © Stewart Lab
People

See the group members, guest scientists, alumni and group pictures here
A woman using a microscope, the object under the microscope can be seen on a connected monitor © Neha Goveas

Our research

Although the complete DNA sequence of an organism encodes the primary information, additional information is added by epigenetic regulation. In higher eukaryotes, epigenetic regulation is conveyed by covalent modifications of DNA (DNA methylation) and histone tails (mainly methylation, acetylation, ubiquitinylation).

We have developed several genetic engineering innovations using site specific and homologous recombination, as well as transposition. Our aim is the fluent manipulation of mammalian genomes.

More about us

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Publica­tions

Our group members publish their findings regularly. Find selected publications here.
Graphical depiction of different types of Bacterial artificial chromosome vector backbones © Madeleine Walker
­Technology Resources

You can find here guidelines for Gene Targeting and Recombineering, as well as a list of our plasmid collection what we sent out.
Touching hands © Gerd Altmann (Pixabay)
Links & Partners

Our lab supports different initiatives. Learn more here.
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Teaching

Our group is involved in several teaching activities at CMCB. Find more about here.
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Jobs

We have currently no open positions.
Get in touch!

If you have any questions regarding our research or if your are interested in a scientific collaboration please contact us.

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Name

Genomics

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Address work

Visiting address:

Biotechnology Center (BIOTEC)
Genomics, room 130 Tatzberg 47/49

01307 Dresden

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Address postal

Postal address:

TUD Dresden University of Technology Center for Molecular and Cellular Bioengineering (CMCB)
Biotechnologisches Zentrum (BIOTEC)
Genomics Juliane Wunderlich

01062 Dresden

work Tel.
fax Fax
+49 351 463-143