Evaluation of the autonomic nervous system - Diagnostics, prediction, prevention [2DSW]
The autonomic nervous system (ANS) controls numerous body functions and shows specific reactions depending on personal conditions. The assessment of the ANS allows extensive statements, for example on the risk of suffering life-threatening illnesses, an assessment of sleep and the recording of stress levels.
Our group is developing novel methods of signal processing in order to be able to make such statements. In addition to the currently established analysis of heart rate variability, we focus at novel measures e.g. the QT interval variability. For their evaluation, innovative approaches have been and are being developed. The aim is a substantial improvement of the diagnostic possibilities, in particular the prediction and prevention, without creating an additional burden for the patients.
As part of the project, a close cooperation is maintained with the group of Prof. Mathias Baumert (The University of Adelaide). More information about the project can be found on the website of Two-Dimensional Signal Warping (2DSW).
Further information can be found on the website of the Research Group Biosignal Processing.
Concept of Two-Dimensional Signal Warping (2DSW; details at http://2dsw.com/)
Publications
- M. Schmidt, M. Baumert, A. Porta, H. Malberg, and S. Zaunseder, “Two-Dimensional Warping for One-Dimensional Signals—Conceptual Framework and Application to ECG Processing,” IEEE Trans. Signal Process., vol. 62, iss. 21, p. 5577–5588, 2014.
- M. Schmidt, M. Baumert, H. Malberg, and S. Zaunseder, “T Wave Amplitude Correction of QT Interval Variability for Improved Repolarization Lability Measurement,” Front. Physiol., vol. 7, 2016.
- M. Schmidt, M. Baumert, H. Malberg, and S. Zaunseder, “Iterative two-dimensional signal warping—Towards a generalized approach for adaption of one-dimensional signals,” Biomedical Signal Processing and Control, vol. 43, p. 311–319, 2018.
- M. Schmidt, M. Baumert, T. Penzel, H. Malberg, and S. Zaunseder, “Nocturnal ventricular repolarization lability predicts cardiovascular mortality in the Sleep Heart Health Study,” American Journal of Physiology-Heart and Circulatory Physiology, vol. 316, no. 3, pp. H495–H505, Dec. 2018.