ZIH-Kolloquium - Modelling Collective Cell Motion in Biology and Medicine

Modelling Collective Cell Motion in Biology and Medicine

Collective cell motion is a common phenomenon in biology - both in normal development and in disease. I will review work that we have been doing on examples in both cases. I will show how, working with experimental colleagues, we have been able to advance knowledge in the biological understanding of cranial neural crest cell invasion, using a hybrid agent-based model. I will then consider the well-known snail-trail model in angiogenesis and show that a systematic derivation starting from a cell-level master equation leads to a coupled system of partial differential equations that are quite different to those in the literature.

Philip K. Maini FRS FMedSci is Director of the Wolfson Centre for Mathematical Biology, Mathematical Institute, Oxford, and Statutory Professor of Mathematical Biology. He was awarded the LMS Naylor Prize in 2009 and the SMB Winfree Prize in 2017.