Publications
2026
Santosh Nirmala S, Hu Y, Floegel FD, Cruz H, Morgenstern J, Platz A, Vollroth M, Fuchs A. Delineating phenotypic heterogeneity in human regulatory T cells across developmental stages and therapeutic sources. Front Immunol. 2026;17:1697723. PMID: 41659850. Delineating phenotypic heterogeneity in human regulatory T cells across developmental stages and therapeutic sources
2025
Lakshmi K, Jutrzenka-Trzebiatowski AV, Loureiro L, Soto KEG, Peter K, Morales JMM, Nirmala SS, Berndt N, Arndt C, Hu Y, Li JW, Peitzsch C, Taubenberger A, Wehner R, Schmitz M, Hölig K, Abken H, Bonifacio E, Bornhäuser M, Bachmann M, Feldmann A, Fuchs A. Automated GMP-compatible production of universal CAR Tregs for organ-targeted tolerance induction. J Transl Med. 2025;23(1):1399. PMID: 41408297. Automated GMP-compatible production of universal CAR Tregs for organ-targeted tolerance induction - Journal of Translational Medicine
Hu Y, Cruz H, Santosh Nirmala S, Fuchs A. Unlocking the therapeutic potential of thymus-isolated regulatory T cells. Front Immunol. 2025;16:1612360. PMID: 40642063. Unlocking the therapeutic potential of thymus-isolated regulatory T cells
2024
Santosh Nirmala S, Kayani K, Gliwiński M, Hu Y, Iwaszkiewicz-Grześ D, Piotrowska-Mieczkowska M, Sakowska J, Tomaszewicz M, Marín Morales JM, Lakshmi K, Marek-Trzonkowska NM, Trzonkowski P, Oo YH, Fuchs A. Beyond FOXP3: a 20-year journey unravelling human regulatory T-cell heterogeneity. Front Immunol. 2024;14:1321228. PMID: 38283365. https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1321228/full
2019
Marín Morales JM, Münch N, Peter K, Freund D, Oelschlägel U, Hölig K, Böhm T, Flach AC, Keßler J, Bonifacio E, Bornhäuser M, Fuchs A. Automated Clinical Grade Expansion of Regulatory T Cells in a Fully Closed System. Front Immunol. 2019;10:38. PMID: 30778344
2018
Fuchs A, Gliwiński M, Grageda N, Spiering R, Abbas AK, Appel S, Bacchetta R, Battaglia M, Berglund D, Blazar B, Bluestone JA, Bornhäuser M, Ten Brinke A, Brusko TM, Cools N, Cuturi MC, Geissler E, Giannoukakis N, Gołab K, Hafler DA, van Ham SM, Hester J, Hippen K, Di Ianni M, Ilic N, Isaacs J, Issa F, Iwaszkiewicz-Grześ D, Jaeckel E, Joosten I, Klatzmann D, Koenen H, van Kooten C, Korsgren O, Kretschmer K, Levings M, Marek-Trzonkowska NM, Martinez-Llordella M, Miljkovic D, Mills KHG, Miranda JP, Piccirillo CA, Putnam AL, Ritter T, Roncarolo MG, Sakaguchi S, Sánchez-Ramón S, Sawitzki B, Sofronic-Milosavljevic L, Sykes M, Tang Q, Vives-Pi M, Waldmann H, Witkowski P, Wood KJ, Gregori S, Hilkens CMU, Lombardi G, Lord P, Martinez-Caceres EM, Trzonkowski P Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization. Front Immunol. 2018; 15;8. PMID:29379498
2016
Theil A,Wilhelm C, Kuhn M, Petzold A, Tuve S, Oelschlägel U, Dahl A, Bornhäuser M, Bonifacio E, Eugster A. T cell receptor repertoires after adoptive transfer of expanded allogeneic regulatory T cells. Clin Exp Immunol. 2016;187(2):316–24. PMID: 27774628
2015
Theil A, Tuve S, Oelschlägel U, Maiwald A, Döhler D, Oßmann D, Zenkel A, Wilhelm C, Middeke JM, Shayegi N, Trautmann-Grill K, von Bonin M, Platzbecker U, Ehninger G, Bonifacio E, Bornhäuser M. Adoptive transfer of allogeneic regulatory T cells into patients with chronic graft-versus-host disease. Cytotherapy 2015;17(4):473–86. PMID: 25573333