Publikationen
AUSGEWÄHLTE PUBLIKATIONEN
Yilmazer A, Eugster E, Zevla DM, Helbich SS, Boernert M, Torun B, Marsela E, Kirgin E, Dahl A, Petzold A, Kershaw O, Alexaki VI, Chatzigeorgiou A, Delacher M, Schlenner S, Kretschmer K. Functional Dichotomy of Developmental Foxp3+ Treg Cell Subsets in the Visceral Adipose Tissue of Lean and Obese Mice. bioRxiv 2025.03.12.642664; doi: https://doi.org/10.1101/2025.03.12.642664
Yilmazer A, Zevla DM, Kretschmer K. Regulatory T cell transdifferentiation as a driver of obesity and diabetes. Front Immunol. 2025 Nov 19;16:1698285. doi: 10.3389/fimmu.2025.1698285. PMID: 41346616; PMCID: PMC12672523.
Yilmazer, A.; Zevla, D.M.; Kretschmer, K. Developmental Origin and Functional Diversity of Foxp3+ Regulatory T Cells in Diabetes and Obesity. Endocrines 2025, 6, 41. https://doi.org/10.3390/endocrines6030041
Yilmazer A, Zevla DM, Malmkvist R, Rodríguez CAB, Undurraga P, Kirgin E, Boernert M, Voehringer D, Kershaw O, Schlenner S*, Kretschmer K*. Selective ablation of thymic and peripheral Foxp3+ regulatory T cell development. Front Immunol. 2023 Dec 18;14:1298938. doi: 10.3389/fimmu.2023.1298938. PMID: 38164128; PMCID: PMC10757929. *Shared senior author.
Simonetti M, Yilmazer A, Kretschmer K. Genetic Tools for Analyzing Foxp3+ Treg Cells: Fluorochrome-Based Transcriptional Reporters and Genetic Fate-Mapping. Methods Mol Biol. 2023;2559:95-114. doi: 10.1007/978-1-0716-2647-4_8. PMID: 36180629.
Dohnke S, Moehser S, Surnov A, Kurth T, Jessberger R, Kretschmer K, Garbe AI. Role of Dynamic Actin Cytoskeleton Remodeling in Foxp3+ Regulatory T Cell Development and Function: Implications for Osteoclastogenesis. Front Immunol. 2022 Mar 11;13:836646. doi: 10.3389/fimmu.2022.836646. PMID: 35359955; PMCID: PMC8963504.
Watts D, Janßen M, Jaykar M, Palmucci F, Weigelt M, Petzold C, Hommel A, Sparwasser T, Bonifacio E, Kretschmer K. Transient Depletion of Foxp3+ Regulatory T Cells Selectively Promotes Aggressive β Cell Autoimmunity in Genetically Susceptible DEREG Mice. Front Immunol. 2021 Aug 10;12:720133. doi: 10.3389/fimmu.2021.720133. PMID: 34447385; PMCID: PMC8382961.
Fischer L, Herkner C, Kitte R, Dohnke S, Riewaldt J, Kretschmer K, Garbe AI. Foxp3+ Regulatory T Cells in Bone and Hematopoietic Homeostasis. Front Endocrinol (Lausanne). 2019 Sep 10;10:578. doi: 10.3389/fendo.2019.00578. PMID: 31551927; PMCID: PMC6746882.
Andreas N, Potthast M, Geiselhöringer AL, Garg G, de Jong R, Riewaldt J, Russkamp D, Riemann M, Girard JP, Blank S, Kretschmer K, Schmidt-Weber C, Korn T, Weih F, Ohnmacht C. RelB Deficiency in Dendritic Cells Protects from Autoimmune Inflammation Due to Spontaneous Accumulation of Tissue T Regulatory Cells. J Immunol. 2019 Nov 15;203(10):2602-2613. doi: 10.4049/jimmunol.1801530. Epub 2019 Oct 2. PMID: 31578269; PMCID: PMC6826119.
Schreiber M, Weigelt M, Karasinsky A, Anastassiadis K, Schallenberg S, Petzold C, Bonifacio E†, Kretschmer K†*, Hommel A†*. Inducible IL-7 Hyperexpression Influences Lymphocyte Homeostasis and Function and Increases Allograft Rejection. Front Immunol. 2019 Apr 10;10:742. doi: 10.3389/fimmu.2019.00742. PMID: 31024566; PMCID: PMC6467976. †Corresponding and *shared senior author.
Walker TL, Schallenberg S, Rund N, Grönnert L, Rust R, Kretschmer K, Kempermann G. T Lymphocytes Contribute to the Control of Baseline Neural Precursor Cell Proliferation but Not the Exercise-Induced Up-Regulation of Adult Hippocampal Neurogenesis. Front Immunol. 2018 Dec 11;9:2856. doi: 10.3389/fimmu.2018.02856. PMID: 30619254; PMCID: PMC6297802.
Dohnke S, Schreiber M, Schallenberg S, Simonetti M, Fischer L, Garbe AI, Chatzigeorgiou A, and Kretschmer K. Approaches to discriminate naturally induced Foxp3+ Treg cells of intra- and extrathymic origin: Helios, Neuropilin-1, and Foxp3RFP/GFP. 2018. J Clin Cell Immunol. 9(1): 540.
Schallenberg S and Kretschmer, K. New insight into type 1 diabetes development: resolving early diabetogenic CD4+ T cell responses that precede seroconversion. Editorial. Ann Transl Med. 2018. Online at: http://dx.doi.org/10.21037/atm.2017.12.14.
Brennecke AM, Düber S, Roy B, Thomsen I, Garbe AI, Klawonn F, Pabst O, Kretschmer K, Weiss S. Induced B Cell Development in Adult Mice. Front Immunol. 2018 Oct 31;9:2483. doi: 10.3389/fimmu.2018.02483. PMID: 30429851; PMCID: PMC6220648. Special Issue: A Tribute to Antonios G. Rolink. Front Immunol. - B Cell Biology
Freudenberg K, Lindner N, Dohnke S, Garbe AI, Schallenberg S*, Kretschmer K*. Critical Role of TGF-β and IL-2 Receptor Signaling in Foxp3 Induction by an Inhibitor of DNA Methylation. Front Immunol. 2018 Feb 2;9:125. doi: 10.3389/fimmu.2018.00125. PMID: 29456534; PMCID: PMC5801288. *Shared senior author.
Tabansky I, Keskin DB, Watts D, Petzold C, Funaro M, Sands W, Wright P, Yunis EJ, Najjar S, Diamond B, Cao Y, Mooney D, Kretschmer K†, Stern JNH†. Targeting DEC-205-DCIR2+dendritic cells promotes immunological tolerance in proteolipid protein-induced experimental autoimmune encephalomyelitis. Mol Med. 2018 May 3;24(1):17. doi: 10.1186/s10020-018-0017-6. PMID: 30134798; PMCID: PMC6016871. †Corresponding author.
Fuchs A, Gliwiński M, Grageda N, Spiering R, Abbas AK, Appel S, Bacchetta R, Battaglia M, Berglund D, Blazar B, Bluestone JA, Bornhäuser M, Ten Brinke A, Brusko TM, Cools N, Cuturi MC, Geissler E, Giannoukakis N, Gołab K, Hafler DA, van Ham SM, Hester J, Hippen K, Di Ianni M, Ilic N, Isaacs J, Issa F, Iwaszkiewicz-Grześ D, Jaeckel E, Joosten I, Klatzmann D, Koenen H, van Kooten C, Korsgren O, Kretschmer K, Levings M, Marek-Trzonkowska NM, Martinez-Llordella M, Miljkovic D, Mills KHG, Miranda JP, Piccirillo CA, Putnam AL, Ritter T, Roncarolo MG, Sakaguchi S, Sánchez-Ramón S, Sawitzki B, Sofronic-Milosavljevic L, Sykes M, Tang Q, Vives-Pi M, Waldmann H, Witkowski P, Wood KJ, Gregori S, Hilkens CMU, Lombardi G, Lord P, Martinez-Caceres EM, Trzonkowski P. Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization. Front Immunol. 2018 Jan 15;8:1844. doi: 10.3389/fimmu.2017.01844. PMID: 29379498; PMCID: PMC5775516.
Wyss L, Stadinski BD, King CG, Schallenberg S, McCarthy NI, Lee JY, Kretschmer K, Terracciano LM, Anderson G, Surh CD, Huseby ES, Palmer E. Affinity for self antigen selects Treg cells with distinct functional properties. Nat Immunol. 2016 Sep;17(9):1093-101. doi: 10.1038/ni.3522. Epub 2016 Aug 1. PMID: 27478940; PMCID: PMC4994872.Top of Form
Spiering R, Margry B, Keijzer C, Petzold C, Hoek A, Wagenaar-Hilbers J, van der Zee R, van Eden W, Kretschmer K, Broere F. DEC205+ Dendritic Cell-Targeted Tolerogenic Vaccination Promotes Immune Tolerance in Experimental Autoimmune Arthritis. J Immunol. 2015 May 15;194(10):4804-13. doi: 10.4049/jimmunol.1400986. Epub 2015 Apr 10. PMID: 25862815.
Warth SC, Hoefig KP, Hiekel A, Schallenberg S, Jovanovic K, Klein L, Kretschmer K, Ansel KM, Heissmeyer V. Induced miR-99a expression represses Mtor cooperatively with miR-150 to promote regulatory T-cell differentiation. EMBO J. 2015 May 5;34(9):1195-213. doi: 10.15252/embj.201489589. Epub 2015 Feb 23. PMID: 25712478; PMCID: PMC4426480.
Chmelova H, Cohrs CM, Chouinard JA, Petzold C, Kuhn M, Chen C, Roeder I, Kretschmer K, Speier S. Distinct roles of β-cell mass and function during type 1 diabetes onset and remission. Diabetes. 2015 Jun;64(6):2148-60. doi: 10.2337/db14-1055. Epub 2015 Jan 20. PMID: 25605805.
Vahl JC, Drees C, Heger K, Heink S, Fischer JC, Nedjic J, Ohkura N, Morikawa H, Poeck H, Schallenberg S, Rieß D, Hein MY, Buch T, Polic B, Schönle A, Zeiser R, Schmitt-Gräff A, Kretschmer K, Klein L, Korn T, Sakaguchi S, Schmidt-Supprian M. Continuous T cell receptor signals maintain a functional regulatory T cell pool. Immunity. 2014 Nov 20;41(5):722-36. doi: 10.1016/j.immuni.2014.10.012. Epub 2014 Nov 6. PMID: 25464853.
Mayer CT, Lahl K, Milanez-Almeida P, Watts D, Dittmer U, Fyhrquist N, Huehn J, Kopf M, Kretschmer K, Rouse B, Sparwasser T. Advantages of Foxp3(+) regulatory T cell depletion using DEREG mice. Immun Inflamm Dis. 2014 Nov;2(3):162-5. doi: 10.1002/iid3.33. Epub 2014 Oct 26. PMID: 25505550; PMCID: PMC4257761.
Petzold C, Steinbronn N, Gereke M, Strasser RH, Sparwasser T, Bruder D, Geffers R, Schallenberg S*, Kretschmer K*. Fluorochrome-based definition of naturally occurring Foxp3(+) regulatory T cells of intra- and extrathymic origin. Eur J Immunol. 2014 Dec;44(12):3632-45. doi: 10.1002/eji.201444750. Epub 2014 Sep 23. PMID: 25159127. *Shared senior author.
Niebling J, E Rünker A, Schallenberg S, Kretschmer K, Kempermann G. Myelin-specific T helper 17 cells promote adult hippocampal neurogenesis through indirect mechanisms. F1000Res. 2014 Jul 24;3:169. doi: 10.12688/f1000research.4439.2. PMID: 25383186; PMCID: PMC4215755.
Wieduwild R, Lin W, Boden A, Kretschmer K, Zhang Y. A repertoire of peptide tags for controlled drug release from injectable noncovalent hydrogel. Biomacromolecules. 2014 Jun 9;15(6):2058-66. doi: 10.1021/bm500186a. Epub 2014 May 21. PMID: 24825401.
Xiao S, Yosef N, Yang J, Wang Y, Zhou L, Zhu C, Wu C, Baloglu E, Schmidt D, Ramesh R, Lobera M, Sundrud MS, Tsai PY, Xiang Z, Wang J, Xu Y, Lin X, Kretschmer K, Rahl PB, Young RA, Zhong Z, Hafler DA, Regev A, Ghosh S, Marson A, Kuchroo VK. Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms. Immunity. 2014 Apr 17;40(4):477-89. doi: 10.1016/j.immuni.2014.04.004. PMID: 24745332; PMCID: PMC4066874.Bottom of FormBottom of Form
Toker A, Engelbert D, Garg G, Polansky JK, Floess S, Miyao T, Baron U, Düber S, Geffers R, Giehr P, Schallenberg S, Kretschmer K, Olek S, Walter J, Weiss S, Hori S, Hamann A, Huehn J. Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus. J Immunol. 2013 Apr 1;190(7):3180-8. doi: 10.4049/jimmunol.1203473. Epub 2013 Feb 18. PMID: 23420886.
Petzold C, Riewaldt J, Watts D, Sparwasser T, Schallenberg S, Kretschmer K. Foxp3(+) regulatory T cells in mouse models of type 1 diabetes. J Diabetes Res. 2013;2013:940710. doi: 10.1155/2013/940710. Epub 2013 Mar 14. PMID: 23691523; PMCID: PMC3647588.
Ritter PS, Kretschmer K, Pfennig A, Soltmann B. Disturbed sleep in bipolar disorder is related to an elevation of IL-6 in peripheral monocytes. Med Hypotheses. 2013 Dec;81(6):1031-3. doi: 10.1016/j.mehy.2013.09.025. Epub 2013 Sep 27. PMID: 24120697.
Schallenberg, S, Petzold S, Riewaldt J, Kretschmer K. Regulatory T Cell-Based Immuno-therapy: Prospects of Antigen-Specific Tolerance Induction. In: Medical Advancements in Aging and Regenerative Technologies: Clinical Tools and Applications, ed. A. Daskalaki. 2013. IGI Global, pp. 112-136.
Heninger AK, Theil A, Wilhelm C, Petzold C, Huebel N, Kretschmer K, Bonifacio E, Monti P. IL-7 abrogates suppressive activity of human CD4+CD25+FOXP3+ regulatory T cells and allows expansion of alloreactive and autoreactive T cells. J Immunol. 2012 Dec 15;189(12):5649-58. doi: 10.4049/jimmunol.1201286. Epub 2012 Nov 5. PMID: 23129754.
Petzold C, Schallenberg S, Stern JN, Kretschmer K. Targeted antigen delivery to DEC-205⁺ dendritic cells for tolerogenic vaccination. Rev Diabet Stud. 2012 Winter;9(4):305-18. doi: 10.1900/RDS.2012.9.305. Epub 2012 Dec 28. PMID: 23804268; PMCID: PMC3740698.
Schallenberg S, Petzold C, Tsai PY, Sparwasser T, Kretschmer K. Vagaries of fluorochrome reporter gene expression in Foxp3+ regulatory T cells. PLoS One. 2012;7(8):e41971. doi: 10.1371/journal.pone.0041971. Epub 2012 Aug 6. PMID: 22879902; PMCID: PMC3412838.
Riewaldt J, Düber S, Boernert M, Krey M, Dembinski M, Weiss S, Garbe AI, Kretschmer K. Severe Developmental B Lymphopoietic Defects in Foxp3-Deficient Mice are Refractory to Adoptive Regulatory T Cell Therapy. Front Immunol. 2012 Jun 5;3:141. doi: 10.3389/fimmu.2012.00141. PMID: 22679447; PMCID: PMC3367401.
Koristka S, Cartellieri M, Theil A, Feldmann A, Arndt C, Stamova S, Michalk I, Töpfer K, Temme A, Kretschmer K, Bornhäuser M, Ehninger G, Schmitz M, Bachmann M. Retargeting of human regulatory T cells by single-chain bispecific antibodies. J Immunol. 2012 Feb 1;188(3):1551-8. doi: 10.4049/jimmunol.1101760. Epub 2011 Dec 19. PMID: 22184723.
Stern JN*†, Keskin DB*, Kato Z, Waldner H, Schallenberg S, Anderson A, von Boehmer H, Kretschmer K*†, Strominger JL†. Promoting tolerance to proteolipid protein-induced experimental autoimmune encephalomyelitis through targeting dendritic cells. Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17280-5. doi: 10.1073/pnas.1010263107. Epub 2010 Sep 20. PMID: 20855626; PMCID: PMC2951396. *Shared first-author and †corresponding author.
Schallenberg S, Tsai PY, Riewaldt J, Kretschmer K. Identification of an immediate Foxp3(-) precursor to Foxp3(+) regulatory T cells in peripheral lymphoid organs of nonmanipulated mice. J Exp Med. 2010 Jul 5;207(7):1393-407. doi: 10.1084/jem.20100045. Epub 2010 Jun 28. PMID: 20584884; PMCID: PMC2901063.
Petzold C, Riewaldt J, Koenig T, Schallenberg S, Kretschmer K. Dendritic cell-targeted pancreatic beta-cell antigen leads to conversion of self-reactive CD4(+) T cells into regulatory T cells and promotes immunotolerance in NOD mice. Rev Diabet Stud. 2010 Spring;7(1):47-61. doi: 10.1900/RDS.2010.7.47. Epub 2010 May 10. PMID: 20703438; PMCID: PMC2923380.
Feuerer M, Hill JA, Kretschmer K, von Boehmer H, Mathis D, Benoist C. Genomic definition of multiple ex vivo regulatory T cell subphenotypes. Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):5919-24. doi: 10.1073/pnas.1002006107. Epub 2010 Mar 15. PMID: 20231436; PMCID: PMC2851866.
Nolting J, Daniel C, Reuter S, Stuelten C, Li P, Sucov H, Kim BG, Letterio JJ, Kretschmer K, Kim HJ, von Boehmer H. Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines. J Exp Med. 2009 Sep 28;206(10):2131-9. doi: 10.1084/jem.20090639. Epub 2009 Sep 8. PMID: 19737861; PMCID: PMC2757891.
Düber S, Hafner M, Krey M, Lienenklaus S, Roy B, Hobeika E, Reth M, Buch T, Waisman A, Kretschmer K*, Weiss S*. Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells. Blood. 2009 Dec 3;114(24):4960-7. doi: 10.1182/blood-2009-04-218156. Epub 2009 Oct 7. PMID: 19812384. *Shared senior author.
Cao Z, Wara AK, Icli B, Sun X, Packard RR, Esen F, Stapleton CJ, Subramaniam M, Kretschmer K, Apostolou I, von Boehmer H, Hansson GK, Spelsberg TC, Libby P, Feinberg MW. Kruppel-like factor KLF10 targets transforming growth factor-beta1 to regulate CD4(+)CD25(-) T cells and T regulatory cells. J Biol Chem. 2009 Sep 11;284(37):24914-24. doi: 10.1074/jbc.M109.000059. Epub 2009 Jul 14. PMID: 19602726; PMCID: PMC2757194.
Polansky JK*, Kretschmer K*, Freyer J, Floess S, Garbe A, Baron U, Olek S, Hamann A, von Boehmer H, Huehn J. DNA methylation controls Foxp3 gene expression. Eur J Immunol. 2008 Jun;38(6):1654-63. doi: 10.1002/eji.200838105. PMID: 18493985. *Co-first author.Bottom of Form
Kretschmer K, Apostolou I, Verginis P, von Boehmer H. Regulatory T cells and antigen-specific tolerance. Chem Immunol Allergy. 2008;94:8-15. doi: 10.1159/000154846. PMID: 18802332.
Kretschmer K, Apostolou I, Verginis P, von Boehmer H. Foxp3 and Regulatory T cells. In: Regulatory T cells and Clinical Application, ed. S. Jiang. 2008. Springer, pp. 17-28.
Apostolou I, Verginis P, Kretschmer K, Polansky J, Hühn J, von Boehmer H. Peripherally induced Treg: mode, stability, and role in specific tolerance. J Clin Immunol. 2008 Nov;28(6):619-24. doi: 10.1007/s10875-008-9254-8. Epub 2008 Oct 8. PMID: 18841451.
Marson A*, Kretschmer K*, Frampton GM, Jacobsen ES, Polansky JK, MacIsaac KD, Levine SS, Fraenkel E, von Boehmer H, Young RA. Foxp3 occupancy and regulation of key target genes during T-cell stimulation. Nature. 2007 Feb 22;445(7130):931-5. doi: 10.1038/nature05478. Epub 2007 Jan 21. PMID: 17237765; PMCID: PMC3008159. *Co-first author.
Stoermann B, Kretschmer K, Düber S, Weiss S. B-1a cells are imprinted by the microenvironment in spleen and peritoneum. Eur J Immunol. 2007 Jun;37(6):1613-20. doi: 10.1002/eji.200636640. PMID: 17492803.
Kretschmer K, Heng TS, von Boehmer H. De novo production of antigen-specific suppressor cells in vivo. Nat Protoc. 2006;1(2):653-61. doi: 10.1038/nprot.2006.105. PMID: 17802642.
Jaeckel E, Kretschmer K, Apostolou I, von Boehmer H. Instruction of Treg commitment in peripheral T cells is suited to reverse autoimmunity. Semin Immunol. 2006 Apr;18(2):89-92. doi: 10.1016/j.smim.2006.01.011. Epub 2006 Feb 13. PMID: 16473523.
Apostolou I, Kretschmer K, von Boehmer H. Peptide-based instruction of suppressor commit-ment in naïve T cells. In: The Autoimmune Diseases, ed. N.R. Rose and I.R. Mackay. 2006. Elsevier, pp. 133-138.
Kretschmer K, Apostolou I, Jaeckel E, Khazaie K, von Boehmer H. Making regulatory T cells with defined antigen specificity: role in autoimmunity and cancer. Immunol Rev. 2006 Aug;212:163-9. doi: 10.1111/j.0105-2896.2006.00411.x. PMID: 16903913.
Kretschmer K, Apostolou I, Hawiger D, Khazaie K, Nussenzweig MC, von Boehmer H. Inducing and expanding regulatory T cell populations by foreign antigen. Nat Immunol. 2005 Dec;6(12):1219-27. doi: 10.1038/ni1265. Epub 2005 Oct 23. PMID: 16244650.
Borsutzky S, Kretschmer K, Becker PD, Mühlradt PF, Kirschning CJ, Weiss S, Guzmán CA. The mucosal adjuvant macrophage-activating lipopeptide-2 directly stimulates B lymphocytes via the TLR2 without the need of accessory cells. J Immunol. 2005 May 15;174(10):6308-13. doi: 10.4049/jimmunol.174.10.6308. PMID: 15879130.
Kretschmer K, Stopkowicz J, Scheffer S, Greten TF, Weiss S. Maintenance of peritoneal B-1a lymphocytes in the absence of the spleen. J Immunol. 2004 Jul 1;173(1):197-204. doi: 10.4049/jimmunol.173.1.197. PMID: 15210775. *Corresponding author.
Kretschmer K*, Jungebloud A, Stopkowicz J, Kleinke T, Hoffmann R, Weiss S. The selection of marginal zone B cells differs from that of B-1a cells. J Immunol. 2003 Dec 15;171(12):6495-501. doi: 10.4049/jimmunol.171.12.6495. PMID: 14662849. *Corresponding author.
Düber S, Engel H, Rolink A, Kretschmer K, Weiss S. Germline transcripts of immunoglobulin light chain variable regions are structurally diverse and differentially expressed. Mol Immunol. 2003 Dec;40(8):509-16. doi: 10.1016/s0161-5890(03)00226-8. PMID: 14563370.
Kretschmer K*, Jungebloud A, Stopkowicz J, Stoermann B, Hoffmann R, Weiss S. Antibody repertoire and gene expression profile: implications for different developmental and functional traits of splenic and peritoneal B-1 lymphocytes. J Immunol. 2003 Aug 1;171(3):1192-201. doi: 10.4049/jimmunol.171.3.1192. PMID: 12874205. *Corresponding author.
Walter U, Toepfer T, Dittmar KE, Kretschmer K, Lauber J, Weiss S, Servos G, Lechner O, Scherbaum WA, Bornstein SR, Von Boehmer H, Buer J. Pancreatic NOD beta cells express MHC class II protein and the frequency of I-A(g7) mRNA-expressing beta cells strongly increases during progression to autoimmune diabetes. Diabetologia. 2003 Aug;46(8):1106-14. doi: 10.1007/s00125-003-1164-y. Epub 2003 Jul 10. PMID: 12856083.
Kretschmer K*, Engel H, Weiss S. Strong antigenic selection shaping the immunoglobulin heavy chain repertoire of B-1a lymphocytes in lambda 2(315) transgenic mice. Eur J Immunol. 2002 Aug;32(8):2317-27. doi: 10.1002/1521-4141(200208)32:8<2317::AID-IMMU2317>3.0.CO;2-0. Erratum in: Eur J Immunol. 2003 Jul;33(7):2064. PMID: 12209645. *Corresponding author.