The Joint Programming Initiative on Antimicrobial Resistance (JPIAMR) has recently launched its sixth Call for Proposals. The primary aim of the call of the Joint Programming Initiative on Antimicrobial Resistance (JPIAMR) is to combine the resources, infrastructures, and research strengths of multiple countries. This will help to identify and validate new targets, develop new therapies as well as new tools for new treatments (including new antibiotics).

The call will only cover research tackling the bacterial pathogens and the resistances identified in the Global priority list of antibiotic-resistant bacteria published by the WHO in September 2017 with the addition of multi- and extensively drug resistant Mycobacterium tuberculosis.

Projects considered for funding will involve fundamental and/or translational research, with the exception of clinical trials.

The proposal should address at least one of the following topics:

New targets:

• Studies of new bacterial targets or mechanisms of resistance (examples include studies on novel enzyme or efflux pump inhibitors or others), including studies aimed at understanding and overcoming the mechanisms controlling the generation of resistance.

New therapies:

• Discovery of new compounds (including new antibiotics and alternatives).
• Strategies to inhibit or reduce the acquisition of resistance, such as single molecular agents effective against multiple targets as well as therapeutics that enhance immune-mediated pathogen elimination, disrupt colonisation or biofilm development, and reduce virulence.
• Discovery of novel therapies to overcome known antimicrobial resistance mechanisms and/or to restore susceptibility to conventional antibiotics.

New tools/assays:

• Strategies and/or innovative tools or assays that improve, enhance, and/or facilitate the identification or validation of new effective compounds or therapies.
• Strategies and/or innovative tools for optimization of drug use, dosage and delivery of new drugs
• Exploration of bacterial genes e.g. expression of latent gene clusters.

Each consortium submitting a proposal must be comprised of a minimum of three research groups. The eligible research groups must be from at least three different countries. The total number of research groups in a consortium is limited to six. Consortia including partners form Czech Republic, Egypt, Latvia, Poland or Romania may increase the total number of partners to seven.

Funding is expected to start in the first half of 2019. The projects will be funded for a period of up to three years.

There will be a two-stage procedure for joint applications to this call. Pre-proposals must be submitted in electronic format no later than 17:00 CET on 7 March, 2018 via the electronic submission system. Successful proposals will be invited by the Joint Call Secretariat to submit a full proposal no later than 17:00 C.E.T. on 14 June 2018.

Please find the Call in full detail at https://www.jpiamr.eu/activities/joint-calls/open-calls/.

In case you have any questions or would like to seek a personal consultation on the funding opportunities, please do not hesitate to contact the EPC staff.

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