GHGA – The German Human Genome-Phenome Archive
GHGA Map
Next-generation sequencing has revolutionized research and allowed scientists to gain deeper insights into the genetic mechanisms of various diseases. These advances have led to improved diagnostics and drug development, enabling patients to receive tailor-made and more effective therapies. A decisive factor for this is a comprehensive collection of data and the exchange with the scientific community in order to achieve the best possible medical impact.
The German Human Genome Phenomenon Archive (GHGA) is funded by the German Research Foundation and creates a secure, GDPR-compliant national infrastructure for the storage of human omics data. The GHGA data portal acts as a central platform for the exchange of Omics data and will also enable a protected analysis of this data in a later phase.
GHGA comprises seven data hubs operated at six NGS competence centres in Germany and is integrated into European infrastructures internationally by serving as the national hub of the European Genome Archive (EGA). In addition, the GHGA data hubs act as genome data centers within the framework of the national model project genomDE and thus promote close cooperation between medical care and scientific research for the development of innovative solutions for personalized medicine.
Together with the DRESDEN-concept Genome Center (DcGC), the Center for Information Services and High-Performance Computing (ZIH) of the TU Dresden forms one of the seven data hubs within the national GHGA network.
For this purpose, ZIH provides the HPC, cloud and storage capacity necessary to use the GHGA infrastructure and adequately archive generated human data sets. Furthermore, the ZIH operates a specialized ETL pipeline that enables accelerated transmission of data and metadata from the Genome Center and supports the DcGC scientists in the execution of their NGS pipelines with high performance computing to ensure the security and performance of their workflows.
Project webpage
Partner
ZIH contact
Project runtime
01/2021–12/2028
Funding
Das GHGA-Konsortium und seine Partner werden von der Deutschen Forschungsgemeinschaft (DFG) im Rahmen der Nationalen Forschungsdateninfrastruktur (NFDI) gefördert.
