Equipment and Technologies

La San Marco Extractor

This high pressure extractor constitutes an obligatory equipment involved in almots every lab project.

Cytiva ÄKTA GO

We apply liquid chromotography to isololate biomolecules (proteins, DNA, RNA). Shown here is a Cytiva ÄKTA GO liquid chromatography system.

Multimodal well plate analyzer

We apply quantiative spectroscopy to derive molecular mechanisms. This includes detection of conformational changes and moelcular interactions, as well as the determination of reaction rates using UV/Vis absorbance, fluorescence (FQ, FP, FRET) and luminescence (spectral, BRET, etc).

Recombinant protein production

The production of highly purified and active biomolecules is at the heart of our bottom-up reconstitution approach. We utilize bacteria, yeast and insect cells as hosts for lab scale (mg - g) recombinant protein production.

Photomanipulation

To study the dynamics of biomolecules (proteins, DNAs, RNAs, etc) we utilize photomanipulation using strong lasers for photoconversion and photbleaching. This allows us to derive diffusion properties from microscopy-based time lapse measurements

Analtical HPLC

We employ analytical HPLC to quantitate interactions among biomolecules (e.g. Protein-DNA complexes) and determine the quaternary structure of proteins.