Fatma Betül Can-Yakac
Lipid-protein interactions as basis for diabetes remission after bariatric surgery
Clinical remission of Type 2 Diabetes after bariatric surgery coincides with an acute increase in lipolysis and, consequently, in free fatty acids in the human blood serum. We aim at understanding the molecular consequences of acutely increased fatty acids on the remodeling of the cellular lipidome, and its implication in altering insulin receptor signaling.
Within this project, we will perform shotgun lipidomics of patient plasma obtained before and after surgery. We will identify fatty acids and lipid species that are significantly altered, which will be then used in cellular models and in vitro membrane systems to study how membrane lipidome remodeling affects cellular signaling.
© PLID
Postdoc
NameDr. Fatma Betül Can-Yakac
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