Group Members
Head
NameProf. Dr. Michele Solimena
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36612
- fax Fax
- +49 351 796-36698
Administrative Coordinator
NameKatja Pfriem
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36612
- fax Fax
- +49 351 796-36698
Administration
NameDana Krüger
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36618
- fax Fax
- +49 351 796-36699
Assistant to Administration
NameMandy Hähnel
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36777
- fax Fax
- +49 351 796-36698
Scientiffic Coordinator
NameDr. Frank Möller
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-5634
- fax Fax
- +49 351 796-36698
Senior Scientist
NameKlaus-Peter Knoch
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36619
- fax Fax
- +49 351 463-36698
Senior Scientist
NameDr. Hassan Mziaut
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36613
- fax Fax
- +49 351 796-36698
Postdoc
NameDr. Inna Kalaidzidis
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36608
- fax Fax
- +49 351 796-36698
---------------------------------------
Postdoc
NameDr. Andreas Müller
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36608
- fax Fax
- +49 351 796-36698
The aim of my project is the ultrastructural analysis of insulin secretory granules (SGs) of different age. Insulin secretion in pancreatic islets occurs in two phases: a short and rapid first phase followed by a sustained second phase. There is evidence of an age dependent release of SGs, i.e. “older” SGs are less likely to undergo exocytosis relative to “younger” SGs. I will use the latest techniques in fluorescence and electron microscopy to investigate the ultrastructure of SGs of different age and their interaction with the cytoskeleton of the beta cell as well the influence of SG markers on SG aging.
---------------------------------------
Postdoc
NameDr. Juha Torkko
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36604
- fax Fax
- +49 351 796-36698
Elevated glucose is the predominant signal to commit beta cells for synthesis of proinsulin and also of other secretory granule associated proteins that undergo regulated processing and maturation for the biogenesis of the secretory-competent insulin granules. The goal of this project is to investigate the role of ICA512/IA-2 and other related factors in the generation and homeostasis of the insulin secretory granule stores.
---------------------------------------
Postdoc
NameDr. Jovana Vasiljevic
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36608
- fax Fax
- +49 351 796-36698
Post-transcriptional regulation is largely responsible for glucose-stimulated proinsulin biosynthesis in beta-cells. A number of RNA-binding proteins, such as PTBP1 and hnRNP K, mediate the glucose-dependent increase in insulin mRNA stability and translation. However, many of the RNA-protein interactions in beta cells are still unknown. My work focuses on identifying the proteins that bind to insulin mRNA in beta cells and investigating their role in insulin expression. Elucidating the composition and activity of protein-RNA complexes is key for a better understanding of the post-transcriptional mechanisms involved in insulin biosynthesis and secretory granule biogenesis.
---------------------------------------
Predoc
NameMarko Barovic MD
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36603
- fax Fax
- +49 351 796-36698
---------------------------------------
Predoc
NameZuzana Marinicova
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36606
- fax Fax
- +49 351 796-36698
---------------------------------------
Predoc
NameMartin Neukam
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36608
- fax Fax
- +49 351 796-36698
---------------------------------------
Technician
NameKatharina Ganß
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36605
- fax Fax
- +49 351 796-36698
Technician
NameCarla Münster
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36615
- fax Fax
- +49 351 796-36698
Technician
NameEyke Schöniger
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36607
- fax Fax
- +49 351 796-36698
Technician
NameAnke Sönmez
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36606
- fax Fax
- +49 351 796-36698
Technician
NameCarolin Wegbrod
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36606
- fax Fax
- +49 351 796-36698
Technician
NameDaniela Richter
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36777
- fax Fax
- +49 351 796-36698
Study Nurse
NameNicole Radisch
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 458-18433
- fax Fax
- +49 351 796-36698
Technician
NameMs Katja Lehmann
Send encrypted mail via the SecureMail portal (for TUD external users only).
- work Tel.
- +49 351 796-36777
- fax Fax
- +49 351 796-36698