Group Members

Head
NameProf. Dr. Michele Solimena
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- work Tel.
- +49 351 796-36612
- fax Fax
- +49 351 796-36698

Administrative Coordinator
NameKatja Pfriem
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- work Tel.
- +49 351 796-36612
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- +49 351 796-36698

Administration
NameDana Krüger
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- work Tel.
- +49 351 796-36618
- fax Fax
- +49 351 796-36699

Administrative Assistance
NameAnnika Hutschreuther-Azizi
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- work Tel.
- +49 351 796-36610
- fax Fax
- +49 351 796-36698

Scientiffic Coordinator
NameDr. Frank Möller
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- work Tel.
- +49 351 796-5634
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- +49 351 796-36698

Senior Scientist
NameKlaus-Peter Knoch
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- work Tel.
- +49 351 796-36619
- fax Fax
- +49 351 463-36698

Senior Scientist
NameDr. Hassan Mziaut
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- work Tel.
- +49 351 796-36613
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- +49 351 796-36698

Postdoc
NameDr. Inna Kalaidzidis
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- work Tel.
- +49 351 796-36608
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- +49 351 796-36698
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Postdoc
NameDr. Andreas Müller
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- +49 351 796-36608
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- +49 351 796-36698
The aim of my project is the ultrastructural analysis of insulin secretory granules (SGs) of different age. Insulin secretion in pancreatic islets occurs in two phases: a short and rapid first phase followed by a sustained second phase. There is evidence of an age dependent release of SGs, i.e. “older” SGs are less likely to undergo exocytosis relative to “younger” SGs. I will use the latest techniques in fluorescence and electron microscopy to investigate the ultrastructure of SGs of different age and their interaction with the cytoskeleton of the beta cell as well the influence of SG markers on SG aging.
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Postdoc
NameDr. Juha Torkko
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- +49 351 796-36604
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Elevated glucose is the predominant signal to commit beta cells for synthesis of proinsulin and also of other secretory granule associated proteins that undergo regulated processing and maturation for the biogenesis of the secretory-competent insulin granules. The goal of this project is to investigate the role of ICA512/IA-2 and other related factors in the generation and homeostasis of the insulin secretory granule stores.
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Postdoc
NameDr. Jovana Vasiljevic
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- +49 351 796-36608
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- +49 351 796-36698
Post-transcriptional regulation is largely responsible for glucose-stimulated proinsulin biosynthesis in beta-cells. A number of RNA-binding proteins, such as PTBP1 and hnRNP K, mediate the glucose-dependent increase in insulin mRNA stability and translation. However, many of the RNA-protein interactions in beta cells are still unknown. My work focuses on identifying the proteins that bind to insulin mRNA in beta cells and investigating their role in insulin expression. Elucidating the composition and activity of protein-RNA complexes is key for a better understanding of the post-transcriptional mechanisms involved in insulin biosynthesis and secretory granule biogenesis.
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Predoc
NameDr. Martin Neukam
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- work Tel.
- +49 351 796-36608
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- +49 351 796-36698

Predoc
NameMarko Barovic MD
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- work Tel.
- +49 351 796-36603
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- +49 351 796-36698
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Predoc
NameZuzana Marinicova
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- work Tel.
- +49 351 796-36606
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- +49 351 796-36698
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Predoc
NameEsteban Quezada Dulcic
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MD student
NameAntonia Kosok
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MD student
NameSebastian Rummeny
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Technician
NameKatharina Ganß
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- work Tel.
- +49 351 796-36605
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- +49 351 796-36698

Technician
NameCarla Münster
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- work Tel.
- +49 351 796-36615
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- +49 351 796-36698

Technician
NameEyke Schöniger
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- work Tel.
- +49 351 796-36607
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- +49 351 796-36698

Technician
NameAnke Sönmez
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- work Tel.
- +49 351 796-36606
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- +49 351 796-36698

Technician
NameCarolin Wegbrod
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- +49 351 796-36606
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- +49 351 796-36698

Technician
NameDaniela Friedland (Richter)
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- work Tel.
- +49 351 796-36777
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- +49 351 796-36698

Study Nurse
NameNicole Kipke
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- work Tel.
- +49 351 458-18433
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- +49 351 796-36698